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Cat. No.	Product Name	Target	Signaling Pathways
T10711	CCR2 antagonist 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).
T13114	CCR2 antagonist 4 Teijin compound 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR2 antagonist 4 (Teijin compound 1) 是高效的、特异性的CCR2拮抗剂，对 CCR2b 的IC50为 180 nM，抑制 MCP-1 诱导的趋化作用的 IC50为 24 nM。
T19230	CCR2 antagonist 4 hydrochloride Teijin compound 1 hydrochloride	Others	Others
	CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).
T14688	BMS CCR2 22	CCR	Immunology/Inflammation; Microbiology/Virology
	BMS CCR2 22 是一种有效的选择性 CC 型趋化因子受体2拮抗剂，钙通量 IC50为 18 nM，趋化性 IC50为1 nM，结合 IC50为5.1 nM。
TQ0297	Cenicriviroc TAK-652,TBR-652	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Cenicriviroc (TAK-652) 是一种可口服的CCR2/CCR5拮抗剂，可抑制 HIV-1 和 HIV-2，具有抗炎、抗感染作用。
T2375	BX471 BX 471,BX-471,ZK-811752	CCR	Immunology/Inflammation; Microbiology/Virology
	BX471 (BX 471) 是可口服的非多肽 CCR1选择性拮抗剂，Ki 值为 1 nM，对其选择性是对 CCR2、CCR5 和 CXCR4 的 250 倍。
T14845	BX471 hydrochloride ZK-811752 hydrochloride	Others	Others
	BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.
T10756	Cenicriviroc Mesylate TBR-652 Mesylate,TAK-652 Mesylate	CCR	Immunology/Inflammation; Microbiology/Virology
	Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2 with anti-inflammatory and antiinfective activity.
T11647	INCB 3284 dimesylate	Others	Others
	INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM). It can be used in the research of acute liver failure.
T11648	INCB 3284	Others	Others
	INCB 3284, a potent and selective human CCR2 antagonist with an oral bioavailability, is utilized in the study of acute liver failure. It effectively inhibits the binding of monocyte chemoattractant protein-1 (MCP-1) to hCCR2, demonstrating an IC50 of 3.7 nM.
T35772	Emestrin
	Emestrin is a mycotoxin originally isolated from E. striata that has antimicrobial, immunomodulatory, and cytotoxic activities.1,2,3,4,5 It is active against the fungi C. albicans and C. neoformans, as well as the bacteria E. coli, S. aureus, and methicillin-resistant S. aureus (MRSA; IC50s = 3.94, 0.6, 2.21, 4.55, and 2.21 μg/ml, respectively).2 Emestrin is a chemokine (C-C motif) receptor 2 (CCR2) antagonist (IC50 = 5.4 μM in a radioligand binding assay using isolated human monocytes).3 Emestr...