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Search Results for " cage "

Targets Recommended: Others

29

抑制剂 & 化合物

4

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T78534	NVOC cage-TMP-Halo	Others	Others
	NVOC cage-TMP-Halo是一种具有细胞渗透能力和光激活特性的蛋白质二聚化诱导剂。该化合物可对活细胞内蛋白质定位进行快速且可逆的控制，适用于研究动态细胞过程。
T14522	Beaucage reagent	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Beaucage reagent 可用于DNA 切割。
T39786	DMNPE-4 AM-caged-calcium
	DMNPE-4 AM-caged-calcium, a photolabile analogue of EGTA, is a highly efficient Ca2+-selective cage. At pH 7.2 and pH 7.4, its Kd for Ca2+ is measured at 48 nM and 19 nM, respectively. Upon photolysis, DMNPE-4 AM-caged-calcium exhibits a decreased affinity for Ca2+ (~2 nM Kd).
T126420	Bellericagenin B
	Bellericagenin B 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126420，CAS号为 109742-48-5。
T23081	NPEC-caged-D-AP5	Others	Others
	NPEC-caged-D-AP5 is a NMDA receptor antagonist.
T16093	Telcagepant MK-0974	Others	Others
	Telcagepant is an orally active antagonist of calcitonin gene-related peptide (CGRP) receptor (Kis: 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively).
T23083	NPEC-caged-LY 379268	Others	Others
	group II mGlu receptor agonist
T23084	NPEC-caged-(S)-3,4-DCPG	Others	Others
	mGlu8a agonist
T23011	MNI-caged-D-aspartate	Others	Others
	Agonist at NMDA receptors and EAAT substrate
T35285	Yuccagenone
	Yuccagenone is a biochemical.
T23079	NPE-caged-proton	Others	Others
	Generates rapid acidifications down to pH 2
T23012	MNI caged kainic acid	Others	Others
	Generates large inward currents at resting membrane potential
T23086	NPEC-caged-serotonin	Others	Others
	5-HT receptor agonist
T23013	MNI-caged-L-glutamate	Others	Others
	rapidly and efficiently releases glutamate
T23085	NPEC-caged-(S)-AMPA	Others	Others
	AMPA receptor agonist
T23082	NPEC-caged-dopamine	Others	Others
	Dopamine receptor agonist
T40973	MDNI-caged-L-glutamate MDNI-caged-L-glutamate,MDNI-glu
	MDNI-glu is a photosensitive derivative of L-glutamate, a major excitatory amino acid, that is biologically inert. It demonstrates improved utilization of incident light.
T61610	NPEC-caged-LY379268
	NPEC-caged-LY379268 是第二组 mGluR 激动剂。
T40889	DMNB-caged-Serine
	DMNB-caged-Serine is a photocaged amino acid . DMNB is a caging group which is sensitive to blue light. DMNB-caged-Serine can be incorporated into proteins in Saccharomyces cerevisiae in response to the amber nonsense codon TAG, which can be helpful for controlling the chemical composition of mammalian proteins..
T22738	DMNPE-caged ATP diammonium salt	Others	Others
	DMNPE-caged ATP
T41208	NB-caged Tyrosine hydrochloride ONBY,NB-caged Tyrosine hydrochloride
	NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitiveortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated intoE.coliproteins via inclusion in growth media.
T23080	NPEC-caged-(1S,3R)-ACPD	Others	Others
	NPEC-caged-(1S,3R)-ACPD is a group I and II mGlu receptor agonist.
T23078	NPE-caged-HPTS	Others	Others
	Caged fluorescent pH indicator
T23014	MNI-caged-NMDA	Others	Others
	NMDA caged with the photosensitive 4-methoxy-7-nitroindolinyl group
T82538	DM-Nitrophen tertasodium
	DM-Nitrophen tertasodium是一种Ca2+笼，能在近紫外光照射下分解释放Ca2+，适用于研究Ca2+信号。
T78241	Asfotase alfa ENB-0040
	Asfotase alfa (ENB-0040) 是一款针对骨骼的基因重组糖蛋白。该药物提升了Akp2−/−基因敲除小鼠的存活率、骨矿化及骨骼生长，并且缓解了脚部、胸部、下肢及颌骨矿化缺损。它主要用于对围产期、婴幼儿及青少年型低磷酸酶血症(HPP)进行研究。
T80899	UNC3474
	UNC3474为小分子配体，与53BP1相结合。该化合物针对53BP1TT的芳香族甲基赖氨酸结合笼展现出1.0 ± 0.3μM的解离常数（Kd）。UNC3474抑制53BP1募集至DSB，其机制为稳定细胞内预存的53BP1自抑制状态。
T83695	MOG Peptide (human, bovine) acetate Myelin Oligodendrocyte Glycoprotein Peptide
	Myelin Oligodendrocyte Glycoprotein (MOG) peptide 是 MOG 的一种内源性肽段截取，存在于髓鞘的细胞外表面。当与抗原血清型HLA-DR2结合时，MOG peptide 在通过中脑动脉阻塞（MCAO）诱导的缺血性中风模型中，能减少皮层和纹状体梗死体积，降低管-角转测试中的感觉运动障碍，增加对新奇气味的探索时间，以及增加雌性（但不是雄性）小鼠对笼伴侣发出的呼叫持续时间。
T72982	DPNB-ABT594
	DPNB-ABT594 是一个硝基苄基 cage 修饰的 ABT594 ，对nAChR 的α4β2亚型的选择性比对 α7 亚型更加良好。DPNB-ABT594 可用于检查内侧缰核 (MHb) 神经元上nAChR 的分布，并有助于更深入地理解nAChR 介导的 Ca2+信号在 MHb 中的作用。

化合物

NVOC cage-TMP-Halo

Cat.No: T78534

Target: Others

Beaucage reagent

Cat.No: T14522

Target: DNA/RNA Synthesis

DMNPE-4 AM-caged-calcium

Cat.No: T39786

Bellericagenin B

Cat.No: T126420

NPEC-caged-D-AP5

Cat.No: T23081

Target: Others

Cat.No: T16093

Synonym: MK-0974

Target: Others

NPEC-caged-LY 379268

Cat.No: T23083

Target: Others

NPEC-caged-(S)-3,4-DCPG

Cat.No: T23084

Target: Others

MNI-caged-D-aspartate

Cat.No: T23011

Target: Others

Cat.No: T35285

NPE-caged-proton

Cat.No: T23079

Target: Others

MNI caged kainic acid

Cat.No: T23012

Target: Others

NPEC-caged-serotonin

Cat.No: T23086

Target: Others

MNI-caged-L-glutamate

Cat.No: T23013

Target: Others

NPEC-caged-(S)-AMPA

Cat.No: T23085

Target: Others

NPEC-caged-dopamine

Cat.No: T23082

Target: Others

MDNI-caged-L-glutamate

Cat.No: T40973

Synonym: MDNI-caged-L-glutamate,MDNI-glu

NPEC-caged-LY379268

Cat.No: T61610

DMNB-caged-Serine

Cat.No: T40889

DMNPE-caged ATP diammonium salt

Cat.No: T22738

Target: Others

NB-caged Tyrosine hydrochloride

Cat.No: T41208

Synonym: ONBY,NB-caged Tyrosine hydrochloride

NPEC-caged-(1S,3R)-ACPD

Cat.No: T23080

Target: Others

NPE-caged-HPTS

Cat.No: T23078

Target: Others

MNI-caged-NMDA

Cat.No: T23014

Target: Others

DM-Nitrophen tertasodium

Cat.No: T82538

Cat.No: T78241

Synonym: ENB-0040

Cat.No: T80899

MOG Peptide (human, bovine) acetate

Cat.No: T83695

Synonym: Myelin Oligodendrocyte Glycoprotein Peptide

Cat.No: T72982

Cat. No.	Product Name	Target	Signaling Pathways
T3387	Phytolaccagenin	Others; Antibacterial	Microbiology/Virology; Others
	Phytolaccagenin 是一种三萜类皂苷，是商陆的活性成分，有抗真菌活性，抗炎活性和较低的毒性。在东亚国家广泛用于治疗炎症相关疾病。
T8167	medicagenic acid Castanogenin,苜蓿酸	Antibacterial	Microbiology/Virology
	Medicagenic acid (Castanogenin) 是从Herniaria glabra L 的根中分离出来的药源酸，对几种植物病原体和人类皮肤癣菌有抑菌作用。
TN2065	Phytolaccagenic acid 美商陆酸	Others	Others
	Phytolaccagenic acid is a natural product
T2749	Ginkgolide A 银杏内酯A,BN-52020	GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Ginkgolide A (BN-52020) 是从银杏叶提取出来的一种天然产物，是 GABA 拮抗剂，有用于多种炎症和免疫疾病的研究潜力。

天然产物

Phytolaccagenin

Cat.No: T3387

Target: Others, Antibacterial

medicagenic acid

Cat.No: T8167

Synonym: Castanogenin,苜蓿酸

Target: Antibacterial

Phytolaccagenic acid

Cat.No: TN2065

Synonym: 美商陆酸

Target: Others

Cat.No: T2749

Synonym: 银杏内酯A,BN-52020

Target: GABA Receptor, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01901	DDX53 Protein, Human, Recombinant (His & Myc) DEAD box protein CAGE,DEAD box protein 53,CAGE<...	Human	E. coli
	N/A. DDX53 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 76.2 kDa and the accession number is Q86TM3.
TMPH-03502	Chaperonin GroEL Protein, Shigella dysenteriae serotype 1, Recombinant (His & Myc & SUMO) groEL,Chaperonin GroEL,hypB,60 kDa chaperonin,groL,Cpn60,mop...	Shigella dysenteriae	E. coli
	Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. Chaperonin GroEL Protein, Shigella dysenteriae serotype 1, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 66.9 kDa and t...
TMPH-00388	Chaperonin GroEL Protein, Chlamydia trachomatis, Recombinant (His & SUMO) Cpn60,mopA,60 kDa chaperonin,Chaperonin-60,Chaperonin GroEL,...	Chlamydia trachomatis	E. coli
	Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. Chaperonin GroEL Protein, Chlamydia trachomatis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 74.0 kDa and the accession number is P0C0...

重组蛋白

DDX53 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01901

Species: Human

Expression System: E. coli

Chaperonin GroEL Protein, Shigella dysenteriae serotype 1, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03502

Species: Shigella dysenteriae

Expression System: E. coli

Chaperonin GroEL Protein, Chlamydia trachomatis, Recombinant (His & SUMO)

Cat.No: TMPH-00388

Species: Chlamydia trachomatis

Expression System: E. coli

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