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Cat. No. Product Name Target Signaling Pathways
T21547 PAF (C16)

C16-PAF

ERK; MEK; MAPK; Endogenous Metabolite MAPK; Metabolism
PAF (C16) 是有效的 MAPK 和 MEK/ERK 激活剂,可诱导血管通透性增加。PAF (C16) (PAF (C16)) 是血小板活化因子,是一种磷脂衍生介质,也是 PAF G 蛋白偶联受体 (PAFR) 的配体。PAF (C16) 在体外实验中显示出抗凋亡和抗炎活性,通过与其受体 (PAF-R) 相互作用以执行细胞信号传导来抑制 caspase 依赖性凋亡。
T37268 PAF C-16 Carboxylic Acid

PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration and the production of reactive oxygen species and IL-6. Pathological processes involving PAF include necrotizing enterocolitis
T36205 Methylcarbamyl PAF C-16

Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. It is nearly equipotent with PAF C-16 in its ability to induce platelet aggregation both in isolated platelets and in platelet-rich plasma. In NRK-49 cells overexpressing the PAF receptor, both PAF C-16 and methylcarbamyl PAF C-16 cause the induction of c-myc and c-fos and the activation of mitogen-activated protein kinase. Methy...

化合物

PAF (C16)
Cat.No: T21547
Synonym: C16-PAF
Target: ERK, MEK, MAPK, Endogenous Metabolite
PAF C-16 Carboxylic Acid
Cat.No: T37268
Synonym:
Target:
Methylcarbamyl PAF C-16
Cat.No: T36205
Synonym:
Target:
TargetMol Loading
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