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Targets Recommended: Others

3

抑制剂 & 化合物

7

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T10598 BR351 precursor

Others Others
BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T10597 BR351

MMP Proteases/Proteasome
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T77906 Briobacept

BR 3FC

Briobacept (BR 3FC)为专门针对BLyS(BAFF)的单克隆抗体,具有诱导B细胞凋亡(apoptosis)的能力。该化合物是一种重组糖蛋白,由两个BLyS受体(BR3)以及人类IgG1 Fc结构域构成。Briobacept主要用于类风湿关节炎(RA)的研究领域。

化合物

BR351 precursor
Cat.No: T10598
Synonym:
Target: Others
BR351
Cat.No: T10597
Synonym:
Target: MMP
Briobacept
Cat.No: T77906
Synonym: BR 3FC
Target:
Cat. No. Product Name Species Expression System
TMPJ-00067 BAFFR/TNFRSF13C Protein, Human, Recombinant (His)

BR3,BAFFR,CD268,TNFRSF13C,BAFF R

Human HEK293 Cells
Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. BAFF promotes the survival of B cells and is essential for B cell maturation. BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF...
TMPK-01254 BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His)

CVID4,prolixin,TNFRSF13C,CD268,BROMIX,BAFF...

Cynomolgus HEK293 Cells
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
TMPK-00070 BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated

CD268,TNFRSF13C,BAFFR,BR3,BR<...

Human HEK293 Cells
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
TMPY-02224 TGFBR3 Protein, Mouse, Recombinant (His)

transforming growth factor, β receptor III,TBRIII,A...

Mouse HEK293 Cells
TGFBR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.3 kDa and the accession number is A0A0R4J097.
TMPY-03649 TGFBR3 Protein, Human, Recombinant (His)

βglycan,betaglycan,transforming growth factor, beta receptor...

Human Baculovirus Insect Cells
TGFBR3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42.2 kDa and the accession number is Q03167-1.
TMPY-03867 CBR3 Protein, Human, Recombinant (His)

SDR21C2,carbonyl reductase 3,hCBR3

Human E. coli
CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo...
TMPJ-00546 EFNA1 Protein, Human, Recombinant (hFc)

TNFAIP4,LERK1,Tumor Necrosis Factor α-Induced Protein 4,Imme...

Human HEK293 Cells
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the...

重组蛋白

BAFFR/TNFRSF13C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00067
Species: Human
Expression System: HEK293 Cells
BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01254
Species: Cynomolgus
Expression System: HEK293 Cells
BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00070
Species: Human
Expression System: HEK293 Cells
TGFBR3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02224
Species: Mouse
Expression System: HEK293 Cells
TGFBR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03649
Species: Human
Expression System: Baculovirus Insect Cells
CBR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03867
Species: Human
Expression System: E. coli
EFNA1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00546
Species: Human
Expression System: HEK293 Cells
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