Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T30460 |
BIR2
Balloon inducing reagent 2,BIR-2,BIR 2,Balloon inducing reagent-2 |
||
BIR2 is a balloon inducing reagent, which triggers a spontaneous self-organization process, leading to the formation of 3-D balloon like structure during hESC differentiation. | |||
T12932L |
SM-164
|
Apoptosis; IAP | Apoptosis |
SM-164 是细胞渗透性 Smac 类似物,与含有 BIR2 和 BIR3 结构域的 XIAP 蛋白结合,IC50值为 1.39 nM,它用作XIAP 的强效拮抗剂。 | |||
T75243 | SM-164 Hydrochloride | ||
SM-164 Hydrochloride 是一种可渗透细胞的 Smac 类似物。SM-164 与含有 BIR2 和 BIR3 结构域的XIAP 蛋白结合,IC50值为 1.39 nM,SM-164 用作XIAP 的强效拮抗剂。 | |||
T12932 |
SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride |
IAP | Apoptosis |
SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP. | |||
T6299 |
GDC-0152
GDC0152 |
IAP | Apoptosis |
GDC-0152 是一种 IAP 抑制剂,可以与 XIAP、cIAP1和cIAP2的 BIR3 结合域,以及ML-IAP 的 BIR 结合域结合,Ki 值分别为 28 nM、17 nM、43 nM 和 14 nM。 |