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Search Results for " atropine "

23

抑制剂 & 化合物

7

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T14345	Atropine methyl bromide 甲溴阿托品,Methylatropine bromide	AChR	Neuroscience
	Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic examination. Compared to atropine, it demonstrates reduced penetration into the central nervous system[1][2]. Its high polarity makes it particularly effective in relieving pyloric spasm in infants.
T30206	Atropine hydrobromide
	Atropine hydrobromide is a biochemical.
T30207	Atropine iodomethylate
	Atropine iodomethylate is a biochemical.
T23763	Atropine Oxide NSC 72861,NSC72861,NSC-72861
	Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and pesticide poisonings as well as som
T69232	Atropine Oxide Hydrochloride
	Atropine Oxide is a derivative of Atropine. Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surgery. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4 and M5. It is classified as an anticholinergic drug (parasympatholytic).
T23524	W-84 dibromide HDMPPA	AChR	Neuroscience
	W-84 dibromide (HDMPPA) 是 M2胆碱受体的强变构调节剂，是一种非竞争性毒蕈碱乙酰胆碱受体拮抗剂，具有变构效应。它联合阿托品时，可有效地防止有机磷中毒。它阻碍 [3H]N-甲基东莨菪碱解离，能稳定胆碱能拮抗剂-受体复合物。
T21673	N-Isopropylnoratropine	Others	Others
	N-Isopropylnoratropine 是一种去甲托品衍生物，是生产异丙托溴铵(ipratropium) 的中间体，异丙托溴铵是一种通过抗胆碱能途径产生的阿托品样支气管扩张药。它用于检查异丙托溴铵的稳定性。
T0427	Homatropine Methylbromide Homatropine methobromide,溴甲基后马托品	AChR	Neuroscience
	Homatropine Methylbromide 是一种毒蕈碱受体 AChR 拮抗剂，抑制 WKY-E 和 SHR-E ，IC50分别为 162.5 和 170.3 nM。
T36204	Methylatropine (nitrate)
	Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 μg/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3 1.Schmeller, T., Sporer, F., Sauerwein, M., et al.Binding of tropane alkaloids to nicotin...
T71631	Eucatropine
	Eucatropine，作为一种有效的毒蕈碱型乙酰胆碱受体(mAChR)抑制剂，具有0.583 μM的IC50值，归类为抗胆碱能剂。
T80637	Homatropine hydrochloride
	Homatropine hydrochloride为口服抗胆碱能剂，迅速扩张瞳孔并导致睫状肌麻痹。该化合物也展现出镇咳效果，适用于眼科疾病和止咳研究。
T23781	Benzatropine Akitan,Benztropine,NK 02,Cogentinol,Cogentine
	Benzatropine is a centrally active muscarinic antagonist. It also inhibits the uptake of dopamine. It has been used in the symptomatic treatment of Parkinson's Disease.
T0629	Atropic acid 2-苯基丙烯酸,Acrylic acid	Others	Others
	Atropic acid (Acrylic acid) 是 Ipratropium bromide 和 Atropine Sulfate 的杂质。
T13118	Temiverine hydrochloride	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Temiverine hydrochloride 是一种潜在的钙离子通道拮抗剂，具有抗胆碱能作用，可抑制阿托品的部分功能。
T0098	Ipratropium bromide monohydrate Ipratropium bromide hydrate,溴化异丙托品单水合物	AChR	Neuroscience
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) 是一种毒蕈碱拮抗剂，结构上与阿托品相关，但它通常被认为对吸入使用更安全、更有效。它用于各种支气管疾病、鼻炎和抗心律失常。
T1281	Tropicamide Ro 1-7683,托吡卡胺	AChR	Neuroscience
	Tropicamide (Ro 1-7683) 是一种选择性的 M4毒蕈碱乙酰胆碱受体拮抗剂，作为滴眼剂使用时，会产生短效瞳孔扩张和睫状肌麻痹。
T6707	Tiotropium Bromide hydrate BA-679 BR hydrate,BA 679BR,噻托溴铵一水合物	AChR	Neuroscience
	Tiotropium Bromide hydrate (BA-679 BR hydrate) 是长效的毒蕈碱受体拮抗剂，可用于治疗慢性阻塞性气道疾病 (COPD)。
T23998	Dihexyverine HCl Olimplex,Neospasmina,Diverine,Dihexyverine hydrochloride,Seclin
	Dihexyverine HCl is an antimuscarinic with effects similar to those of atropine.
T13615	Cinperene 桂哌林,R5046	Others	Others
	Cinperene is an atropine-like compound that can block pilocarpine-induced salivation and lacrimation.
T71029	RCC-36 HCl
	Rcc 36 is an active metabolite of temiverine that has inhibitory actions toward the atropine-resistant part of contractions, which may be related to the calcium antagonistic actions of these compounds.
T69025	Ipratropium Free Base
	Ipratropium Free Base is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
T71236	Oxybutynin R-isomer HCl
	Oxybutynin R-isomer , also known as Aroxybutynin, is a muscarinic receptor antagonist. Aroxybutynin is the optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Oxybutynin exerts direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. It exhibits one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. No blo...
T14614	Biperiden Hydrochloride KL 373 (Hydrochloride),盐酸比哌立登	Others	Others
	Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker and it is used for the adjunctive treatment of all forms of Parkinson's disease (postencephalitic, idiopathic, and arte

化合物

Atropine methyl bromide

Cat.No: T14345

Synonym: 甲溴阿托品,Methylatropine bromide

Target: AChR

Atropine hydrobromide

Cat.No: T30206

Atropine iodomethylate

Cat.No: T30207

Atropine Oxide

Cat.No: T23763

Synonym: NSC 72861,NSC72861,NSC-72861

Atropine Oxide Hydrochloride

Cat.No: T69232

Cat.No: T23524

Synonym: HDMPPA

Target: AChR

N-Isopropylnoratropine

Cat.No: T21673

Target: Others

Homatropine Methylbromide

Cat.No: T0427

Synonym: Homatropine methobromide,溴甲基后马托品

Target: AChR

Methylatropine (nitrate)

Cat.No: T36204

Cat.No: T71631

Homatropine hydrochloride

Cat.No: T80637

Cat.No: T23781

Synonym: Akitan,Benztropine,NK 02,Cogentinol,Cogentine

Cat.No: T0629

Synonym: 2-苯基丙烯酸,Acrylic acid

Target: Others

Temiverine hydrochloride

Cat.No: T13118

Target: Calcium Channel

Ipratropium bromide monohydrate

Cat.No: T0098

Synonym: Ipratropium bromide hydrate,溴化异丙托品单水合物

Target: AChR

Cat.No: T1281

Synonym: Ro 1-7683,托吡卡胺

Target: AChR

Tiotropium Bromide hydrate

Cat.No: T6707

Synonym: BA-679 BR hydrate,BA 679BR,噻托溴铵一水合物

Target: AChR

Dihexyverine HCl

Cat.No: T23998

Synonym: Olimplex,Neospasmina,Diverine,Dihexyverine hydrochloride,Seclin

Cat.No: T13615

Synonym: 桂哌林,R5046

Target: Others

Cat.No: T71029

Ipratropium Free Base

Cat.No: T69025

Oxybutynin R-isomer HCl

Cat.No: T71236

Biperiden Hydrochloride

Cat.No: T14614

Synonym: KL 373 (Hydrochloride),盐酸比哌立登

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0962	L-Hyoscyamine Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺	AChR	Neuroscience
	L-Hyoscyamine (Daturine) 是从山莨菪中提取的一种托烷生物碱，是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。
T4S1619	L-Hyoscyamine sulfate Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐	AChR	Neuroscience
	L-Hyoscyamine sulfate (Levsin Sulfate) 是来自山莨菪的一种托烷生物碱，是竞争性的毒蕈碱受体拮抗剂。它是 Atropine 的左旋异构体。
T33717	Noratropine Norhyoscyamine
	Noratropine is a metabolite of Atropine (A794625).
Fr13711	Tropinone	Others	Others
	Tropinone 是一种可用作合成 Atropine 中间体的生物碱。
T21532	Anisodamine 6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine	AChR	Neuroscience
	Anisodamine (6-beta-Hydroxyhyoscyamine) 是毒蕈碱和烟碱胆碱受体的拮抗剂，对毒蕈碱受体的亲和力与东莨菪碱和阿托品相似。 Anisodamine 改善休克状态下的微循环，可用于有机磷中毒的研究。
T13158	Tigloidin Tiglyssin,Tigloyl pseudotropine,Tiglylpseudotropine	Others	Others
	Tigloidin is an atropine analog with anticholinergic activity.
T32800	Littorine (R)-(-)-Littorine
	Littorine is a tropane alkaloid found in a variety of plants including Datura and Atropa belladonna. It is closely related in chemical structure to atropine, hyoscyamine, and scopolamine, which all share a common biosynthetic pathway.

天然产物

Cat.No: T0962

Synonym: Daturine,Hyoscyamine,L-莨菪碱,L-天仙子胺

Target: AChR

L-Hyoscyamine sulfate

Cat.No: T4S1619

Synonym: Hyoscyamine sulfate hydrate,Levsin Sulfate,Hyoscyamine Sulphate,硫酸天仙子胺水合物,L-莨菪碱硫酸盐

Target: AChR

Cat.No: T33717

Synonym: Norhyoscyamine

Cat.No: Fr13711

Target: Others

Cat.No: T21532

Synonym: 6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine

Target: AChR

Cat.No: T13158

Synonym: Tiglyssin,Tigloyl pseudotropine,Tiglylpseudotropine

Target: Others

Cat.No: T32800

Synonym: (R)-(-)-Littorine

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