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Cat. No.	Product Name	Target	Signaling Pathways
TP1219	Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate ANP (1-28), human, porcineANP(1-28)
	Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 是颗粒鸟苷酸环化酶的刺激剂，已被发现通过增加环鸟苷单磷酸的合成来保护分离的心肌细胞免受复氧诱导的高收缩。Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 也有助于在反复运动期间刺激脂解，并在运动期间控制脂解。
T39244	Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled
	Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs) that exerts endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide holds promise for cardiovascular diseases research.
TP1221	Atrial Natriuretic Peptide (ANP) (1-28), rat Atrial natriuretic factor (1-28) (rat)
	Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.
TP1220L	ANP(1-28) Acetate (human, porcine) 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate	Endothelin Receptor	GPCR/G Protein
	Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate) 是一种由 28 个氨基酸组成的激素，由心脏产生并分泌，以响应心脏损伤和机械拉伸。Carperitide acetate 抑制内皮素-1 (endothelin-1) 分泌。
T41065	Atrial natriuretic factor (1-28) (human, porcine) Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)
	Atrial natriuretic factor (1-28) from both human and porcine sources is a powerful suppressor of pro-opiomelanocortin (POMC) mRNA, while it only has a modest inhibition effect on βEP-LI release.
TP1218	Atrial natriuretic factor (1-28) (rat) TFA Atrial Natriuretic Peptide (ANP) (1-28), rat TFA
	Atrial Natriuretic Peptide (ANP) (1-28),rat (TFA) is the main circulating forms of Atrial Natriuretic Peptide (ANP) in rats, which strongly inhibit the secretion of Ang II - stimulated endothelin-1.
TP1220	Carperitide Atrial Natriuretic Peptide (ANP) (1-28), human, porcine
	Carperitide, a 28-amino acid hormone known as Atrial Natriuretic Peptide (ANP) (1-28), is naturally synthesized and released by the human heart in reaction to cardiac injury and mechanical stretch. This compound effectively suppresses endothelin-1 secretion in a dose-dependent manner.
T82932	Auriculin B Atrial natriuretic peptide(126-150)(rat),ANP (126-150) (Rat)
	Auriculin B (ANP (126-150) (Rat)) 是源自大鼠的心房钠尿肽，具备显著的血管舒张与利尿作用。
T80438	Atrial natriuretic peptide (3-28) (human) ANP (3-28) (human)	Endothelin Receptor	GPCR/G Protein
	Atrial natriuretic peptide (3-28) (human) 是由心房心肌细胞合成并分泌的肽类激素，主要在调节血压、体液平衡及电解质稳态方面发挥作用。
T4200	Sacubitril hemicalcium salt AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt	Neprilysin	Metabolism
	Sacubitril hemicalcium salt (AHU377 calcium salt) 是一种有效的 NEP 抑制剂，IC50=5 nM。它是研究心力衰竭药物 LCZ696 的组分之一。
TP1872	Vasonatrin Peptide (VNP) Vasonatrin Peptide VNP
	Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activity.
T30701	Candoxatrilat UK69578,UK 69578,U 73967,U-73967,U73967,UK-69578
	Candoxatrilat (U 73967, UK69578) is an active neutral endopeptidase inhibitor that reduces atrial natriuretic peptide degradation.
T70471	Cgs 26303
	Cgs 26303 is a potent non-peptidic inhibitor of neutral endopeptidase capable of protecting atrial natriuretic peptide from enzymatic degradation.
T81891	M65
	M65为PAC1受体特异性拮抗剂，可抑制ANP释放。
T76386	ANP (1-30), frog
	ANP (1-30), frog 是蛙源心房肽的多肽片段。具有利钠、利尿和血管松弛作用。
T71987	5-hydroxy Isatin
	5-hydroxy Isatin is an inhibitor of monoamine oxidase A and also inhibits atrial natriuretic peptide-induced activation of particulate guanylyl cyclase in rat brain and heart membranes.
T38641	AP 811
	AP 811, a selective antagonist of the atrial natriuretic peptide clearance receptor (APN-CR, NPR3) with a K i value of 0.48 nM, exhibits remarkable selectivity for NPR3 over NPR1 by more than 20,000-fold. Moreover, AP 811 effectively eliminates ANP-induced pump stimulation.
TP1630	A-71915 TFA (132956-87-7 free base) A-71915 TFA
	A-71915 (TFA) is a selective inhibitor of ANP receptor (atrial natriuretic peptide-receptor), induces apoptosis and decreases insulin secretion in RINm5F pancreatic β-cells.
T82847	BNP (1-21), Pro (Human)
	BNP (1-21), Pro (Human) 是一种由21个氨基酸组成的心脏激素多肽。作为B型利钠肽(BNP)的一部分，与心房利钠肽高度同源，共同构成了心脏的双利钠肽系统。BNP 主要参与心脏发生的调节，并涉及向子宫外环境过渡的生理进程。
T61095	SCH-42354
	SCH-42354 is a potent, orally active inhibitor of neutral endopeptidase (NEP), serving as the active form of the prodrug SCH-42495. By inhibiting NEP hydrolysis, SCH-42354 enhances the activity of atrial natriuretic peptide (ANP) and prevents the hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. Furthermore, SCH-42354 exhibits antihypertensive activity [1] [2].
T76037	A-71915 TFA
	A-71915 (TFA) 为一种选择性心房利钠肽受体 (ANP receptor) 抑制剂，其作用能够诱导 RINm5F 胰腺 β 细胞凋亡，并减少胰岛素释放。
T78007	Vasonatrin Peptide (VNP) TFA
	Vasonatrin Peptide (VNP) TFA 是一种由心钠素 (ANP) 和C型利钠肽 (CNP) 嵌合而成的肽类化合物。它整合了CNP的静脉扩张功能、ANP的利尿效果，并展现出与ANP或CNP无关的特有动脉扩张特性。Vasonatrin Peptide TFA 透过cGMP-PKG信号途径发挥其对内质网应激介导的糖尿病心脏缺血再灌注损害的保护作用。
TP2221	ANP (1-11), rat	Others	Others
	Atrial Natriuretic Peptide (ANP) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide. ANP is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the hom
T82993	AP 811 acetate
	AP 811 acetate是一款选择性的ANP-CR（即NPR3）拮抗剂，其Ki值为0.48 nM。该化合物对NPR3的选择性是对NPR1的两万倍。此外，AP 811 acetate能够消除ANP诱导的泵激活现象。
T82941	Atriopeptin III (rat) ANP 127-150 (rat)
	Atriopeptin III (ANP 127-150) (rat)是包含24个氨基酸的心房肽，作用为有效的血管舒张剂及利尿剂。在输尿管梗阻大鼠模型中，Atriopeptin III (rat)能够改善肾功能并降低血压，同时适用于慢性肾功能衰竭研究。
T83766	Moexiprilat RS 10029
	Moexiprilat是一种血管紧张素转换酶(ACE; IC50 = 2.1 nM)的抑制剂，也是前药moexipril的一种活性代谢产物。通过侧链酯水解作用，在体内从moexipril转化而来。Moexiprilat (10 nM)能防止初生大鼠心脏成纤维细胞在雌激素或血管紧张素II刺激下的增殖。在以每天50 mg/kg剂量给药的去卵巢小鼠中，降低平均动脉血压，并增加心房钠尿肽水平，这是高血压的一个标志。

化合物

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Cat.No: TP1219

Synonym: ANP (1-28), human, porcineANP(1-28)

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled

Cat.No: T39244

Atrial Natriuretic Peptide (ANP) (1-28), rat

Cat.No: TP1221

Synonym: Atrial natriuretic factor (1-28) (rat)

ANP(1-28) Acetate (human, porcine)

Cat.No: TP1220L

Synonym: 醋酸卡培立肽,Carperitide acetate (89213-87-6 Free base),Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Target: Endothelin Receptor

Atrial natriuretic factor (1-28) (human, porcine)

Cat.No: T41065

Synonym: Atrial natriuretic factor (1-28) (human, porcine),Atrial natriuretic peptide (1-28)

Atrial natriuretic factor (1-28) (rat) TFA

Cat.No: TP1218

Synonym: Atrial Natriuretic Peptide (ANP) (1-28), rat TFA

Cat.No: TP1220

Synonym: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine

Cat.No: T82932

Synonym: Atrial natriuretic peptide(126-150)(rat),ANP (126-150) (Rat)

Atrial natriuretic peptide (3-28) (human)

Cat.No: T80438

Synonym: ANP (3-28) (human)

Target: Endothelin Receptor

Sacubitril hemicalcium salt

Cat.No: T4200

Synonym: AHU-377 (hemicalcium salt),LCZ696中间体,AHU377 calcium salt

Target: Neprilysin

Vasonatrin Peptide (VNP)

Cat.No: TP1872

Synonym: Vasonatrin Peptide VNP

Cat.No: T30701

Synonym: UK69578,UK 69578,U 73967,U-73967,U73967,UK-69578

Cat.No: T70471

Cat.No: T81891

ANP (1-30), frog

Cat.No: T76386

5-hydroxy Isatin

Cat.No: T71987

Cat.No: T38641

A-71915 TFA (132956-87-7 free base)

Cat.No: TP1630

Synonym: A-71915 TFA

BNP (1-21), Pro (Human)

Cat.No: T82847

Cat.No: T61095

Cat.No: T76037

Vasonatrin Peptide (VNP) TFA

Cat.No: T78007

ANP (1-11), rat

Cat.No: TP2221

Target: Others

Cat.No: T82993

Atriopeptin III (rat)

Cat.No: T82941

Synonym: ANP 127-150 (rat)

Cat.No: T83766

Synonym: RS 10029

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