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Cat. No. Product Name Target Signaling Pathways
T20765 Atorvastatin

阿托伐他汀,阿伐他汀

HMG-CoA Reductase; Autophagy Autophagy; Metabolism
Atorvastatin 是一种具有口服活性的 HMG-CoA 还原酶抑制剂,通过激活肝细胞色素p450加快代谢,具有有效降低血脂的能力。Atorvastatin 以 IC50 值分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 细胞的增殖和侵袭。Atorvastatin 与氯吡格雷同时服用两种可能会导致患者血栓事件增加。
T3116 Atorvastatin hemicalcium salt

Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis

Ferroptosis; HMG-CoA Reductase; Autophagy Apoptosis; Autophagy; Metabolism
Atorvastatin hemicalcium salt (Atorvastatin Calcium) 是一种口服有效的 HMG-CoA 还原酶抑制剂 ,可用作降低胆固醇的药物。它抑制人 SV-SMC 增殖和侵袭,IC50分别为 0.39 μM 和 2.39 μM。
T14342 Atorvastatin lactone

HMG-CoA Reductase Metabolism
Atorvastatin lactone 是一种 Atorvastatin 的前药。其中 Atorvastatin 是口服具有活力的 3- 羟基 -3- 甲基戊二酰辅酶 A 还原酶抑制剂。
T20887 Atorvastatin Sodium

Lipitor

LDL; Aquaporin; HMG-CoA Reductase Membrane transporter/Ion channel; Metabolism
Atorvastatin Sodium (Lipitor) 是一种HMG-CoA 还原酶的竞争性抑制剂,增加肝细胞上低密度脂蛋白(LDL)受体的表达。Atorvastatin sodium 处理抑制水汽蛋白4来减轻缺血性脑水肿。
TQ0045 2-Hydroxy atorvastatin calcium salt

Drug Metabolite Metabolism
2-Hydroxy atorvastatin calcium salt 是 Atorvastatin 钙盐的羟基代谢物,Atorvastatin 是一种有效的 HMG-CoA 还原酶抑制剂 (IC50 = 8 nM)。
T21363 Atorvastatin calcium trihydrate

CI-981,atorvastatin, calcium salt,CI981,Atorvastatin,CI 981

Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.
T21080 (3S,5S)-Atorvastatin

ent-Atorvastatin,3S,5S-Atorvastatin,(3S,5S)-阿托伐他汀

ent-Atorvastatin is a selective and competitive inhibitor of HMGCR (HMG-CoA reductase).
T69006 Atorvastatin lysine

Atorvastatin lysine is a selective and competitive HMGCR (HMG-CoA reductase) inhibitor.
T10399 Atorvastatin 3-Deoxyhept-2E-Enoic Acid

(2E)-2,3-Dehydroxy Atorvastatin

Others Others
Atorvastatin 3-Deoxyhept-2E-Enoic Acid is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T71560 Atorvastatin magnesium trihydrate

Atorvastatin magnesium trihydrate is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.
T15127 Difluoro atorvastatin

Fluoroatorvastatin

Others Others
Difluoro atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active HMG-CoA reductase inhibitor and it has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion (IC50s: 0.39 μM and
T13562 Atorvastatin methyl ester

Others Others
Atorvastatin methyl ester is a derivative of Atorvastatin. It inhibits the 9-cis-RA-induced Gal4 reporter activity more strongly than Atorvastatin.
T38249 2-Hydroxy atorvastatin lactone

2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].
T10401 Atorvastatin acetonide

Others Others
Atorvastatin acetonide is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T15099 Desfluoro-atorvastatin

Others Others
Desfluoro-atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active inhibitor of HMG-CoA reductase. It has the ability to effectively decrease blood lipids.
T35724 4-hydroxy Atorvastatin (calcium salt)

4-hydroxy Atorvastatin is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias. Atorvastatin is metabolized by the cytochrome P450 (CYP) isoform CYP3A4 to form 4-hydroxy atorvastatin.
T10127 (3R,5S)-Atorvastatin sodium

Others Others
(3R,5S)-Atorvastatin sodium is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T10403 Atorvastatin ethyl ester

Others Others
Atorvastatin ethyl ester, a derivative of Atorvastatin, exhibits potent inhibition of 9-cis-RA-induced Gal4 reporter activity.
T10120 3-Oxo Atorvastatin

Others Others
3-Oxo Atorvastatin is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T30202 Atorvastatin, (3S,5R)-

AT10 Trans

Atorvastatin, (3S,5R)- is an Atorvastatin impurity.
T12283 O-Methyl Atorvastatin hemicalcium

Others Others
O-Methyl Atorvastatin is an impurity of Atorvastatin that is an orally active inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, has the ability to effectively decrease blood lipids.
T10402 Atorvastatin Epoxy Tetrahydrofuran Impurity

Others Others
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor.
T10400 Atorvastatin acetonide tert-butyl ester

Others Others
Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an HMG-CoA reductase inhibitor.
T72101 Atorvastatin hemicalcium trihydrate

阿托伐他汀半钙三水合物,阿托他伐汀半钙三水合物

Atorvastatin hemicalcium trihydrate 是一种具有口服活性的 HMG-CoA 还原酶抑制剂,具有有效降低血脂的能力。Atorvastatin hemicalcium trihydrate 以 IC50值分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 细胞的增殖和侵袭。
T68467 Atorvastatin magnesium

Atorvastatin magnesium is an HMG-CoA inhibitor.
T71492 Atorvastatin strontium

Atorvastatin strontium is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.
T11954 MB-07344

Others Others
MB-07344 has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM.
T11954L MB-07344 sodium

Others Others
MB-07344 sodium has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys. MB-07344 sodium is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM.
T83777 LAU-0901

LAU-0901是一种血小板活化因子(PAF)受体拮抗剂。在体内,LAU-0901(30、60及90 mg/kg)通过减少梗塞体积和改善大鼠由中脑动脉阻塞(MCAO)引起的脑缺血模型中的神经功能来发挥作用。它还能减少同一模型中的小胶质细胞浸润,并增加星形胶质细胞和神经元的存活率。单独使用LAU-0901(30 mg/kg)或与阿托伐他汀联合使用,能减少U87MG胶质母细胞瘤小鼠原位肿瘤模型中的肿瘤生长。
T35799 MBX-8025 (sodium salt)

MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increases in fasting blood glucose and serum insulin levels, and decreases insulin resistance in Alms1 mutant (foz/foz) mice fed an atherogenic diet as a model of diet-induced obesity, type 2 diabetes, and non-alcoholic steatohepatitis (NASH).2 It also decreases serum alanine transamin...

化合物

Atorvastatin
Cat.No: T20765
Synonym: 阿托伐他汀,阿伐他汀
Target: HMG-CoA Reductase, Autophagy
Atorvastatin hemicalcium salt
Cat.No: T3116
Synonym: Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis
Target: Ferroptosis, HMG-CoA Reductase, Autophagy
Atorvastatin lactone
Cat.No: T14342
Synonym:
Target: HMG-CoA Reductase
Atorvastatin Sodium
Cat.No: T20887
Synonym: Lipitor
Target: LDL, Aquaporin, HMG-CoA Reductase
2-Hydroxy atorvastatin calcium salt
Cat.No: TQ0045
Synonym:
Target: Drug Metabolite
Atorvastatin calcium trihydrate
Cat.No: T21363
Synonym: CI-981,atorvastatin, calcium salt,CI981,Atorvastatin,CI 981
Target:
(3S,5S)-Atorvastatin
Cat.No: T21080
Synonym: ent-Atorvastatin,3S,5S-Atorvastatin,(3S,5S)-阿托伐他汀
Target:
Atorvastatin lysine
Cat.No: T69006
Synonym:
Target:
Atorvastatin 3-Deoxyhept-2E-Enoic Acid
Cat.No: T10399
Synonym: (2E)-2,3-Dehydroxy Atorvastatin
Target: Others
Atorvastatin magnesium trihydrate
Cat.No: T71560
Synonym:
Target:
Difluoro atorvastatin
Cat.No: T15127
Synonym: Fluoroatorvastatin
Target: Others
Atorvastatin methyl ester
Cat.No: T13562
Synonym:
Target: Others
2-Hydroxy atorvastatin lactone
Cat.No: T38249
Synonym:
Target:
Atorvastatin acetonide
Cat.No: T10401
Synonym:
Target: Others
Desfluoro-atorvastatin
Cat.No: T15099
Synonym:
Target: Others
4-hydroxy Atorvastatin (calcium salt)
Cat.No: T35724
Synonym:
Target:
(3R,5S)-Atorvastatin sodium
Cat.No: T10127
Synonym:
Target: Others
Atorvastatin ethyl ester
Cat.No: T10403
Synonym:
Target: Others
3-Oxo Atorvastatin
Cat.No: T10120
Synonym:
Target: Others
Atorvastatin, (3S,5R)-
Cat.No: T30202
Synonym: AT10 Trans
Target:
O-Methyl Atorvastatin hemicalcium
Cat.No: T12283
Synonym:
Target: Others
Atorvastatin Epoxy Tetrahydrofuran Impurity
Cat.No: T10402
Synonym:
Target: Others
Atorvastatin acetonide tert-butyl ester
Cat.No: T10400
Synonym:
Target: Others
Atorvastatin hemicalcium trihydrate
Cat.No: T72101
Synonym: 阿托伐他汀半钙三水合物,阿托他伐汀半钙三水合物
Target:
Atorvastatin magnesium
Cat.No: T68467
Synonym:
Target:
Atorvastatin strontium
Cat.No: T71492
Synonym:
Target:
MB-07344
Cat.No: T11954
Synonym:
Target: Others
MB-07344 sodium
Cat.No: T11954L
Synonym:
Target: Others
LAU-0901
Cat.No: T83777
Synonym:
Target:
MBX-8025 (sodium salt)
Cat.No: T35799
Synonym:
Target:
TargetMol Loading
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