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Cat. No. | Product Name | Target | Signaling Pathways |
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T61637 |
Anti-inflammatory agent 8
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Anti-inflammatory agent 8 (compound 13) designated as an anti-inflammatory agent 8, displays enhanced activity on the COX-2 enzyme compared to COX-1, with an IC50 value of 0.09 nM. Furthermore, anti-inflammatory agent 8 exhibits oral bioavailability [1]. | |||
T72413 |
Antimicrobial agent-6
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Antimicrobial agent-6 是一种抗菌剂 (antimicrobial),对革兰氏阳性和革兰氏阴性细菌的 MIC 范围为 4-8 μg/mL。Antimicrobial agent-6 也具有抗炎活性。 | |||
T72414 |
Antimicrobial agent-8
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Antimicrobial agent-8 是一种有效的抗菌剂,对革兰氏阴性和革兰氏阳性菌表现出强大的抗菌活性,MIC 范围为 2-8 μg/mL。Antimicrobial agent-8 对脂多糖引起的炎症表现出抗炎活性。 | |||
T74954 | Antimicrobial agent-9 | ||
Antimicrobial agent-9 (Compound 16) 作为一种抗菌剂,其对革兰氏阳性及革兰氏阴性细菌表现出2-8 μg/mL的最小抑菌浓度(MIC)。此外,Antimicrobial agent-9 还展现了抗炎活性。 | |||
T74953 |
Antimicrobial agent-7
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Antimicrobial agent-7 (Compound 12) 为一化合物,对革兰氏阴性及革兰氏阳性菌展现出显著的抗菌能力,MIC值介于 2-8 μg/mL 之间。此外,该化合物还对脂多糖引发的炎症有着抗炎作用。 | |||
T72506 |
Antioxidant agent-8
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Antioxidant agent-8是一种口服活性的Aβ1-42沉积抑制剂。其抑制原纤维聚集的IC50值为11.15 µM,促进原纤维分解的IC50值为6.87 µM。此外,Antioxidant agent-8对Cu2+诱导的Aβ1-42原纤维聚集有抑制作用(IC50=3.69 µM),并能促进Cu2+诱导的Aβ1-42原纤维分解(IC50=3.35 µM)。该化合物具备抗氧化活性、抗炎活性、生物安全性、血脑屏障通透性和神经保护作用。 | |||
T60292 |
Ibuprofen sodium
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Ibuprofen ((±)-Ibuprofen) sodium 是一种口服活性的选择性COX-1抑制剂,IC50值为 13 μM。Ibuprofen sodium 抑制细胞增殖、血管生成,并诱导细胞凋亡 (apoptosis)。Ibuprofen sodium 是一种非甾体抗炎剂和一氧化氮 (NO) 供体。Ibuprofen sodium 可用于疼痛、肿胀、炎症、感染、免疫学、癌症的研究。 | |||
T78855 |
Anticancer agent 157
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NO Synthase | Immunology/Inflammation |
Anticanceragent 157(compound 15)是一种NO抑制剂,具有抗炎和抗癌特性,IC50值为0.62 μg/mL。它能够与iNOS和caspase 8结合,进而导致核断裂和染色质浓缩,从而诱导细胞凋亡。此外,Anticanceragent 157在不同癌细胞系中展现出显著的抑制活性,对HT29结肠癌细胞的IC50为2.45 μg/mL,对Hep-G2肝癌细胞的IC50为3.25 μg/mL,以及对B16-F10鼠黑色素瘤细胞的IC50为3.84 μg/mL。 | |||
T36660 |
Olsalazine-13C6
Olsalazine-13C6 |
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Olsalazine-13C6is intended for use as an internal standard for the quantification of olsalazine by GC- or LC-MS. Olsalazine is an orally bioavailable prodrug form of the anti-inflammatory agent 5-aminosalicylic acid that is cleaved by bacterial azo reductases in the gut to generate active 5-ASA.1In vitro, olsalazine increases ion transport in isolated rabbit distal ileum when applied to the luminal side (ED50= 0.3 mM) and stimulates fluid transport in rat jejunum when used at a concentration of ... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN1347 |
8-Prenylkaempferol
去甲脱水淫羊藿黄素 |
p38 MAPK; NF-κB; PI3K | MAPK; NF-κB; PI3K/Akt/mTOR signaling |
8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and |