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Cat. No.	Product Name	Target	Signaling Pathways
T1445	Agomelatine Thymanax,S-20098,Valdoxan,阿戈美拉汀	Melatonin Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	Agomelatine (Valdoxan) 是褪黑激素受体的强效激动剂和 5-羟色胺-2C (5-HT2C) 受体的拮抗剂，在猪和人 5-HT2C 克隆受体中pKi 分别为 6.4 和 6.2。
T60523	Agomelatine hydrochloride S-20098 hydrochloride	MT Receptor	Neuroscience
	Agomelatine hydrochloride (S-20098 hydrochloride) (S-20098 hydrochloride) 是特异性的MT1和MT2受体激动剂，对 CHO-hMT1的Ki 值为0.1 nM，对HEK-hMT1的Ki 值为0.06 nM，对CHO-hMT2的Ki 值为0.12 nM，对HEK-hMT2 的Ki 值为0.27 nM。Agomelatine hydrochloride 是选择性的5-羟色胺2C(5-HT2C)受体拮抗剂，对天然 (猪) 和克隆的人 5-HT2C 受体的pKi 值分别为 6.4 和 6.2。
T10266	Agomelatine-d6 Agomelatine D6,S-20098 D6	Others	Others
	Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors.
T10114	3-Hydroxy agomelatine	5-HT Receptor	GPCR/G Protein; Neuroscience
	3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).
T10113	3-Hydroxy agomelatine D3	5-HT Receptor	GPCR/G Protein; Neuroscience
	3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).
T10193	7-Desmethyl-agomelatine	Others	Others
	7-Desmethyl-agomelatine is a metabolite of Agomelatine and has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.
T19162	7-Desmethyl-agomelatine D3	Others	Others
	7-Desmethyl-agomelatine D3 is a deuterium labeled 7-Desmethyl-agomelatine. 7-Desmethyl-agomelatine is a metabolite of Agomelatine.
T10267	Agomelatine (L(+)-Tartaric acid) 阿戈美拉汀 L(+)-酒石酸,S-20098 L(+)-Tartaric acid	5-HT Receptor	GPCR/G Protein; Neuroscience
	Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2). It also is a selective 5-HT2C receptor antagonist (pKis: 6.4 and 6.2 at native (porcine) and cloned (human) 5-HT2C receptors).
T10192	7-Desmethyl-3-hydroxyagomelatine 3-Hydroxy-7-desmethyl agomelatine	5-HT Receptor	GPCR/G Protein; Neuroscience
	7-Desmethyl-3-hydroxyagomelatine is a metabolite of Agomelatine and has less activity than Agomelatine. Agomelatine is a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.
T9898	2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride	Others	Others
	2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride 是抗抑郁药 Agomelatine 的杂质。
T9896	7-Methoxy-1-naphthylacetonitrile	Others	Others
	7-Methoxy-1-naphthylacetonitrile 是抗抑郁药阿戈美拉汀的杂质之一。