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Search Results for " acetylcholine chloride "

14

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1682	Methacholine Chloride 醋甲胆碱,Mecholyl chloride,氯化乙酰甲胆碱,Acetyl-β-methylcholine chloride	AChR	Neuroscience
	Methacholine Chloride (Acetyl-β-methylcholine chloride) 是副交感神经系统中的毒蕈碱-3 受体激动剂。它可用于测量气道高反应性，作为评估哮喘样症状和正常静息呼气流速的诊断辅助手段。它直接作用于平滑肌上的乙酰胆碱受体，引起收缩和气道狭窄。
T3126	Bethanechol chloride (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride	AChR	Neuroscience
	Bethanechol chloride (Carbamyl-β-methylcholine chloride) 是一种拟副交感神经剂，是毒蕈碱型受体 (mAChR) 激动剂，通过直接刺激副交感神经系统的 mAChR 发挥作用。
T0401	Benzethonium chloride Hyamine,Phemeride,苄索氯铵,Quatrachlor	AChR	Neuroscience
	Benzethonium chloride (Quatrachlor) 是合成季铵盐，具有表面活性剂、防腐剂和广谱抗菌特性。它作用于在爪蟾卵母细胞，抑制人重组α7和α4β2神经元烟碱性乙酰胆碱受体。
T22371	Mivacurium dichloride 米库氯铵,Mivacurium chloride,二氯美维库铵	AChR	Neuroscience
	Mivacurium dichloride (Mivacurium chloride) 是苄基异喹啉衍生物，可与 nAChR 偶联，以减少或抑制乙酰胆碱对肌肉细胞末端盘的去极化作用。它也是非去极化短效的神经肌肉阻滞剂和骨骼肌松弛剂。
T1472	Trospium chloride Spasmex,Sanctura,曲司氯铵,曲司氯胺	AChR	Neuroscience
	Trospium chloride (Spasmex) 是一种可口服的特异竞争性毒蕈碱胆碱能受体拮抗剂，可与毒蕈碱受体 M1、M2 和 M3 高亲和力结合，具有抗毒蕈碱活性。
T1049	Oxybutynin chloride Oxybutynin hydrochloride,盐酸奥昔布宁,Oxybutynin HCl	Potassium Channel; AChR	Membrane transporter/Ion channel; Neuroscience
	Oxybutynin chloride (Oxybutynin HCl) 是一种抗胆碱能药物，用于缓解泌尿和膀胱困难。它抑制血管 Kv 通道，IC50为 11.51 μM。
T27199	Doxacurium Chloride BW A 938U,BWA938U,Nuromax,BW-A-938U
	Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.
T60253	(±)-Muscarine chloride
	(±)-Muscarine chloride 是 Muscarine chloride 的外消旋体。Muscarine 是一种原型毒蕈碱乙酰胆碱受体 (mAChR) 激动剂。
T71889	Esoxybutynin Chloride
	Esoxybutynin Chloride is (S)-enantiomer of oxybutynin. Esoxybutynin Chloride exerts antimuscarinic properties. Racemic oxybutynin is used clinically to treat urinary incontinence. Sepracor was developing (S)-oxybutynin, a single-isomer version of Alza's Ditropan (racemic oxybutynin), a muscarinic acetylcholine receptor antagonist, as a potential treatment for urinary incontinence.
T69024	Homidium Cl
	Homidium Chloride is the chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular biology, the bromide salt of ethidium is used to detect and visualize DNA after electrophoresis or in cytochemical preparations. In veterinary pharmacology, it is used as a trypanosomicide. Ethidium bromide and chloride are toxic substances and potent noncompetitive antagonists of the nicotinic acetylcholine receptor.
T71758	Ambenonium chloride
	Ambenonium Chloride is the chloride salt form of ambenonium, a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia gravis occurs when the body produces antibodies against acetylcholine receptors, and thus inhibits signal transmission across the myoneural junction. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereb...
T69158	Ambenonium chloride tetrahydrate
	Ambenonium chloride tetrahydrate is a salt of ambenonium --- a quaternary ammonium compound with parasympathomimetic activity. It is a cholinesterase inhibitor used in the management of myasthenia gravis. Myasthenia gravis occurs when the body produces antibodies against acetylcholine receptors, and thus inhibits signal transmission across the myoneural junction. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that reversibly blocks the activity of acetylcholinesterase, thereb...
T70153	Pipoxolan hydrochloride
	Pipoxolan (HCl) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual cramp...
T69661	Pipoxolan (free base)
	Pipoxolan (free base) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual...

化合物

Methacholine Chloride

Cat.No: T1682

Synonym: 醋甲胆碱,Mecholyl chloride,氯化乙酰甲胆碱,Acetyl-β-methylcholine chloride

Target: AChR

Bethanechol chloride

Cat.No: T3126

Synonym: (±)-Bethanechol,Urecholine,Myocholine,氯贝胆碱,Carbamyl-β-methylcholine chloride

Target: AChR

Benzethonium chloride

Cat.No: T0401

Synonym: Hyamine,Phemeride,苄索氯铵,Quatrachlor

Target: AChR

Mivacurium dichloride

Cat.No: T22371

Synonym: 米库氯铵,Mivacurium chloride,二氯美维库铵

Target: AChR

Trospium chloride

Cat.No: T1472

Synonym: Spasmex,Sanctura,曲司氯铵,曲司氯胺

Target: AChR

Oxybutynin chloride

Cat.No: T1049

Synonym: Oxybutynin hydrochloride,盐酸奥昔布宁,Oxybutynin HCl

Target: Potassium Channel, AChR

Doxacurium Chloride

Cat.No: T27199

Synonym: BW A 938U,BWA938U,Nuromax,BW-A-938U

(±)-Muscarine chloride

Cat.No: T60253

Esoxybutynin Chloride

Cat.No: T71889

Cat.No: T69024

Ambenonium chloride

Cat.No: T71758

Ambenonium chloride tetrahydrate

Cat.No: T69158

Pipoxolan hydrochloride

Cat.No: T70153

Pipoxolan (free base)

Cat.No: T69661

Cat. No.	Product Name	Target	Signaling Pathways
T1221	Acetylcholine chloride ACh chloride,Pilofrin,氯化乙酰胆碱	Calcium Channel; Endogenous Metabolite; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Acetylcholine chloride (Pilofrin) 是一种神经递质，是胆碱能激动剂，通过刺激烟碱乙酰胆碱受体调节多巴胺能神经元活性，在体外抑制 p53 突变肽的聚集。
T1039	Choline chloride Biocolina,Biocoline,Hepacholine,氯化胆碱	AChR	Neuroscience
	Choline chloride (Biocoline) 是一种必需营养素，可激活 α7 烟碱受体，具有抗炎、镇痛的活性。对动脉粥样硬化、神经系统疾病和肝脏疾病等具有影响。
T5855	Edrophonium chloride	AChE	Neuroscience
	Edrophonium chloride 是一种乙酰胆碱酯酶抑制剂，可通过特异性结合其催化位点来防止神经递质乙酰胆碱的分解。

天然产物

Acetylcholine chloride

Cat.No: T1221

Synonym: ACh chloride,Pilofrin,氯化乙酰胆碱

Target: Calcium Channel, Endogenous Metabolite, AChR

Choline chloride

Cat.No: T1039

Synonym: Biocolina,Biocoline,Hepacholine,氯化胆碱

Target: AChR

Edrophonium chloride

Cat.No: T5855

Target: AChE

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