Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6087 |
AZD 6482
KIN 193,AZD6482 |
DNA-PK; PI3K; Autophagy | Autophagy; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
AZD 6482 (AZD6482) 是一种有效的选择性p110β抑制剂,IC50为 0.69 nM。它也是 PI3Kβ 抑制剂,IC50 为 10 nM。 | |||
T12658 |
(Rac)-AZD 6482
(Rac)-KIN-193 |
Others | Others |
(Rac)-AZD 6482 is the racemate of AZD 6482. AZD 6482 is a potent and selective inhibitor of p110β (IC50 of 0.69 nM). | |||
T30261 |
AZD6482 (S-isomer)
AZD-6482,AZD 6482,AZD6482 (S),AZD6482 |
||
AZD6482 (S-isomer) is a potent, selective, ATP-competitive PI3Kβ inhibitor (IC(50) 0.01 μm), which can inhibit insulin-induced in vitro glucose uptake by human adipocytes (IC(50) is 4.4 μm). |