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Targets Recommended: NAMPT Transferase Autophagy

3

抑制剂 & 化合物

20

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T2644 (E)-Daporinad

Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈

NAMPT; Transferase; Autophagy Autophagy; Metabolism
(E)-Daporinad (FK866) 是一种烟酰胺磷酸核糖基转移酶的小分子抑制剂,具有潜在的抗肿瘤和抗血管生成活性,IC50为 0.09 nM。
T27228 E-3030 free acid

E-3030,E3030,E 3030

E-3030 free acid is a peroxisome proliferator-activated receptor (PPAR) agonist. E-3030 decreased blood glucose, triglyceride, non-esterified fatty acids, and insulin levels and increased blood adiponectin levels. Triglyceride- and non-high-density lipopr
T37148 TML-6

TML-6, an oral curcumin derivative, demonstrates inhibitory effects on the synthesis of β-amyloid precursor protein and β-amyloid (Aβ). Additionally, TML-6 exhibits upregulation of Apo E, suppression of NF-κB and mTOR, and enhancement of the anti-oxidative Nrf2 gene activity. Considering its diverse pharmacological profile, TML-6 holds promise as a valuable research tool for investigating Alzheimer's disease (AD)[1].

化合物

(E)-Daporinad
Cat.No: T2644
Synonym: Daporinad,(E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE,APO866,FK866,达珀利奈
Target: NAMPT, Transferase, Autophagy
E-3030 free acid
Cat.No: T27228
Synonym: E-3030,E3030,E 3030
Target:
TML-6
Cat.No: T37148
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00805 Apolipoprotein E/APOE Protein, Mouse, Recombinant (His)

Apo-E,APOE,Apolipoprotein E

Mouse HEK293 Cells
Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. APOE is usually secreted in plasma. Phosphorylation sites are present in the extracellular medium.
TMPK-00788 Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc)

apolipo E,Apo-E,Apolipoprotein E,...

Mouse HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells wi...
TMPJ-00756 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His)

Apolipoprotein E,Apo-E,APOE,A...

Human HEK293 Cells
ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipoproteins (HDL) involved in cholesterol transport .ApoE mediates high affinity binding of chylomicrons and vLDL particles to the LDL receptor, allowing for specific uptake of these particles by the liver, preventing the accumulation of cholesterol rich particles in the plasma .Apo...
TMPK-00589 Apolipoprotein E/APOE4 Protein, Human, Recombinant (His)

APOE,apolipo E,Apo-E,APO...

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPK-00762 Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc)

APOE,Apo-E,Apolipoprotein E,A...

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells w...
TMPH-02421 APOE Protein, Cynomolgus, Recombinant (His & Myc)

Apolipoprotein E,Apo-E,APOE

Cynomolgus E. coli
APOE Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.0 kDa and the accession number is P10517.
TMPH-03199 APOE Protein, Rabbit, Recombinant (His & Myc & SUMO)

APOE,Apolipoprotein E,Apo-E

Rabbit E. coli
APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.6 kDa and the accession number is P18287.
TMPK-00588 Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc)

Apolipoprotein E,Apo-E,apolipo E,...

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells w...
TMPK-00763 Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

APOE3,Apo-E,apolipo E,Apo

Human HEK293 Cells
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated i...
TMPY-05297 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)

LPG,apolipoprotein E,ApoE4,APO-E,...

Human E. coli
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPY-05528 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated

APO-E,LDLCQ5,LPG,ApoE4,AD2,apolip...

Human E. coli
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPJ-01447 Apolipoprotein B-100/APOB Protein, Human, Recombinant (His)

APOB,ApolipoproteinB-100

Human E. coli
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
TMPH-03329 Mcpt2 Protein, Rat, Recombinant (His & Myc)

Rat E. coli
This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates. Mcpt2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P00770.
TMPK-01424 Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)

MHC,HLA-E*01:03,Peptide Ready

Human HEK293 Cells
HLA-E*01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E*01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01545 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

sHLA-E,MHC,MHC class I antigen E,HLAE,MHC HLA-E alpha-1,MHC ...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01423 Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,Peptide Ready,HLA-E*01:03

Human HEK293 Cells
HLA-E*01:03&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-E*01:03. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01541 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated

QA1,MHC HLA-E alpha-2.1,MHC,HLAE,MHC class I antigen E,MHC H...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01544 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)

MHC class I antigen E,HLAE,sHLA-E,QA1,MHC HLA-E alpha-2.1,MH...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01452 HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)

HLAE,MHC class I antigen E,MHC,QA1,sHLA-E

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...
TMPK-01514 HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)

sHLA-E,MHC class I antigen E,MHC HLA-E alpha-1,MHC,HLAE,QA1,...

Human HEK293 Cells
HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules ...

重组蛋白

Apolipoprotein E/APOE Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00805
Species: Mouse
Expression System: HEK293 Cells
Apolipoprotein E/APOE Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00788
Species: Mouse
Expression System: HEK293 Cells
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00756
Species: Human
Expression System: HEK293 Cells
Apolipoprotein E/APOE4 Protein, Human, Recombinant (His)
Cat.No: TMPK-00589
Species: Human
Expression System: HEK293 Cells
Apolipoprotein E/APOE3 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00762
Species: Human
Expression System: HEK293 Cells
APOE Protein, Cynomolgus, Recombinant (His & Myc)
Cat.No: TMPH-02421
Species: Cynomolgus
Expression System: E. coli
APOE Protein, Rabbit, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03199
Species: Rabbit
Expression System: E. coli
Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00588
Species: Human
Expression System: HEK293 Cells
Apolipoprotein E/APOE3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00763
Species: Human
Expression System: HEK293 Cells
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)
Cat.No: TMPY-05297
Species: Human
Expression System: E. coli
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated
Cat.No: TMPY-05528
Species: Human
Expression System: E. coli
Apolipoprotein B-100/APOB Protein, Human, Recombinant (His)
Cat.No: TMPJ-01447
Species: Human
Expression System: E. coli
Mcpt2 Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03329
Species: Rat
Expression System: E. coli
Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01424
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01545
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-E*01:03&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01423
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01541
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01544
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01452
Species: Human
Expression System: HEK293 Cells
HLA-E*01:03&B2M&Peptide (VMAPRTLVL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01514
Species: Human
Expression System: HEK293 Cells
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