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4

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T38099 APF

APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxim...
T80743 Z-APF-CMK

Z-APF-CMK为特异性CRNSP (Ca2+-调节的核支架蛋白酶) 抑制剂。
T78432 Suc-AAPF-pNA

Suc-Ala-Ala-Pro-Phe-pNA

Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA)为一种对硝基苯胺(pNA)显色底物,具备 1.7 mM 的Km值。它适用于定量分析人中性粒细胞内的游离及膜结合形式的组织蛋白酶G活性。
T81822 MeOSuc-AAPF-CMK

MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl

MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH2Cl) 是蛋白酶 K 抑制剂,具有较高效能。

化合物

APF
Cat.No: T38099
Synonym:
Target:
Z-APF-CMK
Cat.No: T80743
Synonym:
Target:
Suc-AAPF-pNA
Cat.No: T78432
Synonym: Suc-Ala-Ala-Pro-Phe-pNA
Target:
MeOSuc-AAPF-CMK
Cat.No: T81822
Synonym: MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl
Target:
Cat. No. Product Name Target Signaling Pathways
TN1040 Skullcapflavone II

COX; Antibacterial; TGF-beta/Smad Immunology/Inflammation; Microbiology/Virology; Neuroscience; Stem Cells
Skullcapflavone II 是从黄芩中提取的黄酮,具有抗炎作用。它对 M. aurum 和 M. bovisBCG 具有较强的抗菌活性。它还调节破骨细胞的分化、存活和功能。
TN5033 Skullcapflavone I

IL Receptor; Caspase; Prostaglandin Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I se

天然产物

Skullcapflavone II
Cat.No: TN1040
Synonym:
Target: COX, Antibacterial, TGF-beta/Smad
Skullcapflavone I
Cat.No: TN5033
Synonym:
Target: IL Receptor, Caspase, Prostaglandin Receptor
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