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Cat. No.	Product Name	Target	Signaling Pathways
T29112	VPC171 (2-氨基-4-(3-(三氟甲基)苯基)噻吩-3-基)(苯基)甲酮,VPC 171,VPC-171	Adenosine Receptor	GPCR/G Protein; Neuroscience
	VPC171 是一种新型腺苷 A1 受体正变构调节剂 (PAM)。
T15623	JNJ-61432059	iGluR	Membrane transporter/Ion channel; Neuroscience
	JNJ-61432059 是具有口服活性的选择性 AMPAR 负向调节剂，对 GluA1/γ-8 的 pIC50值为9.7。
T10774	CFM-2	iGluR	Membrane transporter/Ion channel; Neuroscience
	CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models.
T16524	Philanthotoxin 74 dihydrochloride PhTx-74 HCl,PhTx 74 dihydrochloride	GluR; iGluR	Membrane transporter/Ion channel; Neuroscience
	Philanthotoxin 74 dihydrochloride 是一种 AMPAR 拮抗剂，对 GluR3 和 GluR1 的 IC50 分别为 263 和 296 nM。
T17179	Tulrampator CX-1632,S-47445	iGluR	Membrane transporter/Ion channel; Neuroscience
	Tulrampator (S-47445) 是一种可口服的 AMPA 受体正变构调节剂。具有抗抑郁作用。
T12187L	Naspm trihydrochloride 1-Naphthylacetyl spermine trihydrochloride	iGluR	Membrane transporter/Ion channel; Neuroscience
	Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) 是Joro 蜘蛛毒素的合成类似物，具有拮抗CP-AMPA 受体的活性。
T23267	(RS)-AMPA hydrobromide	Others	Others
	AMPAR agonist
T31979	GNE-3476 GNE 3476
	GNE-3476 is an NMDA receptor PAM. Ge-3476 has different degrees of activity on different receptors.GNE-3476 has relatively low efficacy on GluN2A, some activity as an AMPAR PAM, and weak activity at GluN2B-containing receptors.
T13480L	(S)-(-)-5-Fluorowillardiine hydrochloride (S)-5-Fluorowillardiine hydrochloride,(5S)-Fluorowillardiine hydrochloride	Others	Others
	(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific agonist of AMPAR.
T78971	AMPA receptor modulator-4	iGluR	Membrane transporter/Ion channel; Neuroscience
	AMPA receptor modulator-4 是一种口服有效的 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide (BTD) 类 AMPA 受体正变构调节剂 (AMPAR PAM)。该化合物能穿透血脑屏障，能够增强小鼠的认知能力并改善其工作记忆。
T16505	PF-4778574	Others	Others
	PF-4778574 is a positive AMPA receptor allosteric modulation (EC50: 45 to 919 nM in different cells).