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Targets Recommended: FABP

4

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T4534 BMS-309403

FABP Metabolism
BMS309403 是有效的、选择性脂肪细胞脂肪酸结合蛋白 aFABP 抑制剂。它可改善载脂蛋白 E 缺乏症小鼠和培养的人内皮细胞的内皮功能。它能够与蛋白质内部的脂肪酸结合口袋相互作用,竞争性地抑制内源性脂肪酸的结合。
T15506 HTS01037

Others Others
HTS01037 is an inhibitor of fatty acid-binding. HTS01037 is a competitive antagonist of protein-protein interactions mediated by AFABP/aP2 (Ki: 0.67 μM).
T37614 LDN-0088050

LDN 0088050 is selectivity adipocyte fatty acid binding protein (AFABP, FABP4) inhibitor with Ki values of 0.29 and 1.3 μM for FABP4 and FABP3, respectively. LDN 0088050 binds to FABP4 with a Kd of 2.05 μM[1]. Ki: 0.29 μM (FABP4), 1.3 μM (FABP3)[1]Kd: 2.05 μM (FABP4)[1] LDN 0088050 significantly inhibits LPS-induced expression of both TNFα and IL-6 in RAW264.7 cells[1]. [1]. Zhou Y, et al. The discovery of novel and selective fatty acid binding protein 4 inhibitors by virtual screening and biolo...
T63355 BMS-309403 sodium

BMS-309403 sodium 是一种有效的选择性脂肪细胞脂肪酸结合蛋白aFABP, 也称为FABP4,aP2抑制剂,对 FABP4,FABP3 和 FABP5 的Ki 分别为 <2 nM,250 nM,350 nM。BMS-309403 sodium 与蛋白质内部的脂肪酸结合口袋相互作用,竞争性地抑制内源性脂肪酸的结合。BMS-309403 sodium 可改善载脂蛋白E 缺乏症小鼠和培养的人内皮细胞的内皮功能。

化合物

BMS-309403
Cat.No: T4534
Synonym:
Target: FABP
HTS01037
Cat.No: T15506
Synonym:
Target: Others
LDN-0088050
Cat.No: T37614
Synonym:
Target:
BMS-309403 sodium
Cat.No: T63355
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02103 FABP4 Protein, Human, Recombinant (29 Ala/Thr, His)

HEL-S-104,fatty acid binding protein 4, adipocyte,A-FABP,

Human E. coli
FABP4 Protein, Human, Recombinant (29 Ala/Thr, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16 kDa and the accession number is P15090.

重组蛋白

FABP4 Protein, Human, Recombinant (29 Ala/Thr, His)
Cat.No: TMPY-02103
Species: Human
Expression System: E. coli
TargetMol Loading
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