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抑制剂 & 化合物

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天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T36175	AAPH
	AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces molecular nitrogen and 2 carbon radicals. The carbon radicals may combine to produce stable products or react with molecular oxygen to give peroxyl radicals. The half-life of AAPH is about 175 hours (37°C at neutral pH), making the rate of free radical generation essentially con...

化合物

Cat.No: T36175

Cat. No.	Product Name	Target	Signaling Pathways
TN1256	3-O-Acetyl-16α-hydroxytrametenolic acid 3-O-乙酰基-16Α-羟基-氢化松苓酸,3-O-Acetyl-16 alpha-hydroxytrametenolic acid	Immunology/Inflammation related	Immunology/Inflammation
	3-O-Acetyl-16α-hydroxytrametenolic acid 是茯苓中的一种萜类物质，具有抗氧化、抗癌作用。
T6S0781	Phellodendrine 黄柏碱,Phallodendrin	Others; NF-κB; Akt	Cytoskeletal Signaling; NF-κB; Others; PI3K/Akt/mTOR signaling
	Phellodendrine (Phallodendrin) 是异喹啉生物碱，是黄柏皮层中的重要特征成分之一。它具有良好的抗氧化，抗炎作用。它通过调节AKT/NF-κB 途径抵抗 AAPH 诱导的氧化应激。
TN1007	3-Epidehydrotumulosic acid	Others	Others
	3-Epidehydrotumulosic acid exhibits inhibitory effects on AAPH-induced haemolysis of erythrocytes.
T70891	Pyridoxatin
	Pyridoxatin is a fungal metabolite that inhibits production of thiobarbituric acid reactive substance (TBARS). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH and is active against C. albicans.
TN3380	Alloisoimperatorin	AChR	Neuroscience
	Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoimperatorin has estrogenic activity

天然产物

3-O-Acetyl-16α-hydroxytrametenolic acid

Cat.No: TN1256

Synonym: 3-O-乙酰基-16Α-羟基-氢化松苓酸,3-O-Acetyl-16 alpha-hydroxytrametenolic acid

Target: Immunology/Inflammation related

Cat.No: T6S0781

Synonym: 黄柏碱,Phallodendrin

Target: Others, NF-κB, Akt

3-Epidehydrotumulosic acid

Cat.No: TN1007

Target: Others

Cat.No: T70891

Alloisoimperatorin

Cat.No: TN3380

Target: AChR

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