Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36832 |
PDE4B-IN-2
A 33 |
PDE | Metabolism |
PDE4B-IN-2 (A 33) 是一种具有口服活性,选择性 PDE4B 抑制剂,IC50 为 15 nM。PDE4B-IN-2 抑制 PDE4D (IC50=1.7 µM)。PDE4B-IN-2 表现出有效的抗炎作用。 | |||
T40950 | A3334 | ||
A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD) and methionine-choline deficient diet (MCD). | |||
T83226 | A3373 | Phospholipase | Metabolism |
A3373 是新型 PLD1 和 PLD2 抑制剂,对 PLD1 的 IC50 为 325 nM ,对 PLD2 的 IC50 为 15.15 µM,能够有效抑制 LPS 诱导的免疫反应,并在自身免疫性关节炎、骨脱矿及破骨细胞生成等方面发挥关键作用。 | |||
T68826 |
A33903
|
||
A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus. This molecule was moderately active and demonstrated good pharmacokinetic properties. | |||
T26480 |
A331440
A-331440,A331440 free base,A 331440 |
||
A331440 is an modulator of L-histidine and histamine H3 receptor. | |||
T22935 |
LU AA33810
|
Others | Others |
neuropeptide Y (NPY) Y5 receptor antagonist |