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Cat. No.	Product Name	Target	Signaling Pathways
T14073	A-485	Epigenetic Reader Domain; Histone Acetyltransferase	Chromatin/Epigenetic
	A-485 是 p300/CBP 的一种选择性催化抑制剂，对 p300和 CBP 组蛋白乙酰转移酶的 IC50值分别为 9.8 和 2.6 nM。
T8838	CCI-007	Apoptosis; Histone Methyltransferase	Apoptosis; Chromatin/Epigenetic
	CCI 007 是一种具有细胞毒性的选择性白血病抑制剂，在MLL 重排的敏感系婴幼儿白血病细胞中，IC50为2.5-6.2 μM。
T29536	AC 485 AC-485,AC485
	AC 485 is a biochemical.
T18993	Fluorescein di(β-D-galactopyranoside) FDG	Others	Others
	Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λem=535 nm, λex=485 nm).
T37656	MIT-PZR
	MIT-PZR is a mitochondria-targeted fluorescent probe.1It is aggregation-induced emission (AIE) active and displays absorption/emission maxima of 485/705 nm, respectively. MIT-PZR can be used in live cells andin vivo. 1.Dong, Y., Chen, Z., Hou, L., et al.Mitochondria-targeted aggregation-induced emission active near infrared fluorescent probe for real-time imagingSpectrochim. Acta. A. Mol. Biomol. Spectrosc.224117456(2019)
T38370	CAY10731
	CAY10731 is a fluorescent probe for hydrogen sulfide (H2S).[1] Upon reaction with H2S, fluorescein (FITC) is released and its fluorescence can be used to detect H2S. FITC displays excitation/emission maxima of 485/535 nm, respectively. CAY10731 is selective for H2S over glutathione (GSH), cysteine, H2O3-, SO3-, and H2O2 as well as tBuO and OH radicals. It has been used to detect H2S in rat hippocampal slices and nematodes.
T40210	eIF4E-IN-3 eIF4E-IN-3
	eIF4E-IN-3 is a highly effective inhibitor of eukaryotic initiation factor 4e (eIF4e), exhibiting noteworthy potential for investigating eIF4e dependent diseases, particularly cancer research (WO2021003157A1, compound 485).
T79758	BQZ-485	Apoptosis	Apoptosis
	BQZ-485是一种有效的GDI2抑制剂，它通过与Tyr245相互作用以破坏GDI2-Rab1A之间的内在相互作用，阻断了从内质网(ER)至高尔基体的囊泡转运，并触发了随后的凋亡事件。
T41172	FAM-DEALA-Hyp-YIPD
	FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide (Kd= 180-560 nM). Can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity. Excitation maximum = 485 nm, emission maximum = 535 nm. Longer peptide version, FAM-DEALAHypYIPMDDDFQLRSF, also available.
T35880	Renin Fluorogenic Substrate
	The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. After cleavage by renin, the product (peptide-EDANS) is brightly fluorescent and can be easily analyzed using an excitation wavelength of 340 nm and emission wavelengths of 485-510 nm.
T37090	Indo-1 (potassium salt)
	Indo-1 (potassium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when Indo-1 (potassium salt) binds calcium. Indo-1 (potassium salt) is prone to photobleaching, which limits its usefulness in methods involving microscopy.
T82811	BTC tetrapotassium
	BTC tetrapotassium是一种钙指示剂，其Kd值约为7-26 µM，表现出低亲和力。它拥有适合细胞钙成像的特性，如长激发波长（400/485 nm），低对Mg2+的灵敏度，以及用于比率测量的高准确性。
T41173	FAM-DEALAHypYIPMDDDFQLRSF
	FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluorescence polarization (FP) displacement assay. Excitation/emission maxima (λ) = 485/520 nm. This product is a longer peptide version of FAM-DEALA-Hyp-YIPD.
T37091	Indo-1 (sodium salt)
	Indo-1 (sodium salt) is a ratiometric fluorescent calcium indicator. It is ideal for analyses using flow cytometry, as it uses a single excitation source, typically 349-364 nm light from an argon-ion laser. The emission maximum shifts from 475-485 nm without calcium to 400-410 nm when Indo-1 (sodium salt) binds calcium. Indo-1 (sodium salt) is prone to photobleaching, which limits its usefulness in methods involving microscopy.
T63980	BODIPY FL prazosin
	BODIPY FL prazosin 是荧光 α1-肾上腺素 α1-adrenergic 拮抗剂，能够作用于 α1a-AR (Ki: 14.5 nM)和 α1b-AR (Ki: 43.3 nM)。BODIPY FL prazosin 是一种荧光配体，激发和发射波长分别为 485 和 535 nm。BODIPY FL prazosin 能够用于 α1-肾上腺素受体亚型的亚细胞定位差异的研究。
T35549	Elsinochrome A
	Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus monkey embryonic stem cells and HCe-8693 colorectal carcinoma cells when used at concentrations ranging from 1 to 100 μM. 1.Ma, L., Tai, H., Li, C., et al.Photodynamic inhibitory effects of three perylenequinones on human colorectal carcinoma cell line and primate embryonic stem ...

化合物

Cat.No: T14073

Target: Epigenetic Reader Domain, Histone Acetyltransferase

Cat.No: T8838

Target: Apoptosis, Histone Methyltransferase

Cat.No: T29536

Synonym: AC-485,AC485

Fluorescein di(β-D-galactopyranoside)

Cat.No: T18993

Synonym: FDG

Target: Others

Cat.No: T37656

Cat.No: T38370

Cat.No: T40210

Synonym: eIF4E-IN-3

Cat.No: T79758

Target: Apoptosis

FAM-DEALA-Hyp-YIPD

Cat.No: T41172

Renin Fluorogenic Substrate

Cat.No: T35880

Indo-1 (potassium salt)

Cat.No: T37090

BTC tetrapotassium

Cat.No: T82811

FAM-DEALAHypYIPMDDDFQLRSF

Cat.No: T41173

Indo-1 (sodium salt)

Cat.No: T37091

BODIPY FL prazosin

Cat.No: T63980

Cat.No: T35549

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