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Search Results for " 7-羟基香豆素 "

6

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T77674	3-Cyano-7-hydroxycoumarin 3-Cyanoumbelliferone
	3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone) 是一种巨噬细胞游走抑制因子 (MIF) 互变异构酶抑制剂，Ki 为 2.9 μM。3-Cyano-7-hydroxycoumarin 属于香豆素衍生物，可被用作分子探针和荧光染料。
TD0074	N-Succinimidyl 7-hydroxycoumarin-3-carboxylate 7-羟基-3-羧基香豆素琥珀酰亚胺酯,7-Hydroxycoumarin-3-carboxylic acid, succinimidyl ester
	7-Hydroxycoumarin-3-carboxylic acid, SE is the amine-reactive succinimidyl ester of 7-Hydroxycoumarin-3-carboxylic acid. This coumarin is also increasingly used to label peptides, nucleotides and carbohydrates.
TD0076	AMCA-H N-succinimidyl ester 7-Hydroxy-4-methylcoumarin-3-acetic acid, succinimidyl ester,7-羟基-4-甲基香豆素-3-乙酸琥珀酰亚胺酯
	The amine-reactive AMCA, SE (7-amino-4-methylcoumarin-3-acetic acid, succinimidyl ester) and its conjugates yield blue-fluorescence (approximate excitation/emission maxima ~353/442) that can be used as a contrasting color in multicolor applications.
TD0073	7-Hydroxycoumarin-3-carboxylic acid
	7-Hydroxycoumarin-3-carboxylic acid is a blue fluorophores for labeling proteins and nucleic acids mostly through the in situ formation of its succinimidyl ester catalyzed by EDAC.
TD0075	7-Hydroxy-4-methylcoumarin-3-acetic acid
	7-Hydroxy-4-methylcoumarin-3-acetic acid is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. This coumarin is increasingly used to label peptides, nucleotides and carbohydrates.
T78135	Nicotelline Nicotellin
	Nicotelline（Nicotellin）是一种与尼古丁相关的生物碱，作为人类cDNA表达的细胞色素P-450 2A6（CYP2A6）的弱抑制剂，不显著抑制该酶介导的香豆素7-羟基化反应，在300 μM浓度下效果更是如此。此外，Nicotelline还被用作烟草烟雾中颗粒物（PM）的示踪剂和生物标记物。

化合物

3-Cyano-7-hydroxycoumarin

Cat.No: T77674

Synonym: 3-Cyanoumbelliferone

N-Succinimidyl 7-hydroxycoumarin-3-carboxylate

Cat.No: TD0074

Synonym: 7-羟基-3-羧基香豆素琥珀酰亚胺酯,7-Hydroxycoumarin-3-carboxylic acid, succinimidyl ester

AMCA-H N-succinimidyl ester

Cat.No: TD0076

Synonym: 7-Hydroxy-4-methylcoumarin-3-acetic acid, succinimidyl ester,7-羟基-4-甲基香豆素-3-乙酸琥珀酰亚胺酯

7-Hydroxycoumarin-3-carboxylic acid

Cat.No: TD0073

7-Hydroxy-4-methylcoumarin-3-acetic acid

Cat.No: TD0075

Cat.No: T78135

Synonym: Nicotellin

Cat. No.	Product Name	Target	Signaling Pathways
T1693	Umbelliferone Skimmetine,Hydrangin,Hydrangine,7-羟基香豆素,7-Hydroxycoumarin,NSC 19790	Apoptosis; Antioxidant; Endogenous Metabolite	Apoptosis; Metabolism; oxidation-reduction
	Umbelliferone (7-Hydroxycoumarin) 是香豆素家族的天然荧光化合物，可用作防晒剂。
T4137	4,7-DIHYDROXYCOUMARIN	Others	Others
	4,7-DIHYDROXYCOUMARIN 是一种天然存在的香豆素衍生物，存在于多种植物中，包括欧芹和洋甘菊。已经发现它可以抑制几种酶的活性，包括细胞色素P450、环氧合酶和脂氧合酶；也可以与DNA 结合，调节基因表达，并抑制细胞周期进展；还可以诱导肿瘤细胞凋亡并减轻炎症。
T7993	8-Acetyl-7-Hydroxycoumarin	Antifungal	Microbiology/Virology
	8-Acetyl-7-Hydroxycoumarin 是一种天然化合物，具有抗真菌和抗菌活性。
TJS0328	Nordalbergin 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素	Others	Others
	Nordalbergin 是一种香豆素，分离自Dalbergia sissoo 的木皮中。它能够显著性的诱导 HL-60 细胞的分化。
T5070	LC3-mHTT-IN-AN2 5,7-二羟基-4-苯基香豆素,5,7-Dihydroxy-4-phenylcoumarin	Antibacterial; Autophagy; ATTECs	Autophagy; Microbiology/Virology; PROTAC
	LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) 是一种 mHTT-LC3 接头化合物，可与突变亨廷顿蛋白(mHTT) 和 LC3B 相互作用。它将 mHTT 靶向自噬体以等位基因选择性方式降低培养的亨廷顿病小鼠神经元中的 mHTT 水平。它存在于西番莲植物中，具有抗菌活性。
TJS0314	5,7-Dihydroxy-4-methylcoumarin Methyl-2H-Chromen-2-One,5,7-二羟基-4-甲基香豆素,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin	Others; Antibacterial; Antifungal	Microbiology/Virology; Others
	5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) 是墨西哥龙蒿中的一种香豆素衍生物。它抑制人类中性粒细胞氧化代谢和弹性蛋白酶活性，有抗真菌和抗细菌活性。
TJS0312	7-hydroxy-4-methyl-8-nitrocoumarin	Others	Others
	7-Hydroxy-4-methyl-8-nitrocoumarin 是香豆素衍生物的一种。
T37345	5,7-Dihydroxycoumarin	Antibacterial	Microbiology/Virology
	5,7-Dihydroxycoumarin 是分离自Macaranga triloba 花序的香豆素，具有抗菌活性。
TN4236	Hydrangetin 7-Hydroxy-8-methoxycoumarin	Others	Others
	Hydrangetin (7-Hydroxy-8-methoxycoumarin) 是一种来自 Daphne papyracea var 的小分子化合物，可抑制血小板聚集。

天然产物

Cat.No: T1693

Synonym: Skimmetine,Hydrangin,Hydrangine,7-羟基香豆素,7-Hydroxycoumarin,NSC 19790

Target: Apoptosis, Antioxidant, Endogenous Metabolite

4,7-DIHYDROXYCOUMARIN

Cat.No: T4137

Target: Others

8-Acetyl-7-Hydroxycoumarin

Cat.No: T7993

Target: Antifungal

Cat.No: TJS0328

Synonym: 6,7-dihydroxy-4-phenylcoumarin,6,7-Dihydroxy-4-Phenylchromen-2-One,6,7-二羟基-4苯基香豆素

Target: Others

LC3-mHTT-IN-AN2

Cat.No: T5070

Synonym: 5,7-二羟基-4-苯基香豆素,5,7-Dihydroxy-4-phenylcoumarin

Target: Antibacterial, Autophagy, ATTECs

5,7-Dihydroxy-4-methylcoumarin

Cat.No: TJS0314

Synonym: Methyl-2H-Chromen-2-One,5,7-二羟基-4-甲基香豆素,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin

Target: Others, Antibacterial, Antifungal

7-hydroxy-4-methyl-8-nitrocoumarin

Cat.No: TJS0312

Target: Others

5,7-Dihydroxycoumarin

Cat.No: T37345

Target: Antibacterial

Cat.No: TN4236

Synonym: 7-Hydroxy-8-methoxycoumarin

Target: Others

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