Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13336 |
VTP50469
|
Apoptosis; Epigenetic Reader Domain; Histone Methyltransferase | Apoptosis; Chromatin/Epigenetic |
VTP50469 是一种高选择性和口服活性的Menin-MLL 相互作用抑制剂,具有有效的抗白血病活性,Ki 为 104 pM。 | |||
T69846 |
VTP50469 mesylate
|
||
VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations. | |||
T13336L |
VTP50469 fumarate
|
Others | Others |
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity. |