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Search Results for " 11β-hsd-1-in-1 "

2

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T10160 11β-HSD1-IN-1

Dehydrogenase Metabolism
11β-HSD1-IN-11β 羟类固醇脱氢酶Ⅰ型(11β-HSD1,IC50:52nM)的抑制剂,用于治疗疼痛。
T61593 11β-HSD1-IN-6

11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs). These enzymes are responsible for catalyzing the conversion of the active glucocorticoids, corticosterone or cortisol, to their respective inactive forms, 11-dehydrocorticosterone (11-DHC) and cortisone. The compound 11β-HSD1-IN-6 specifically targets and inhibits 11β-HSD-1, effectively modulating the interconversion of these glucocorticoids. [1]

化合物

11β-HSD1-IN-1
Cat.No: T10160
Synonym:
Target: Dehydrogenase
11β-HSD1-IN-6
Cat.No: T61593
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN4584 Morolic acid

IL Receptor; COX; HIV Protease Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro
TN4585 Moronic acid

HIV Protease; Antifection; HSV Microbiology/Virology; Proteases/Proteasome
Moronic acid shows oral therapeutic efficacy in HSV-infected mice and possessed novel anti-HSV activity. It also shows significant anti-HIV activity (EC(50) 186) and was modified to develop more potent anti-AIDS agents. Moronic acid is a new structural lead for anti-EBV drug development, can substantially reduce the numbers of EBV particles produced by the cells after lytic induction. Morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an...

天然产物

Morolic acid
Cat.No: TN4584
Synonym:
Target: IL Receptor, COX, HIV Protease
Moronic acid
Cat.No: TN4585
Synonym:
Target: HIV Protease, Antifection, HSV
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