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Cat. No. | Product Name | Target | Signaling Pathways |
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T70808 |
Cabazitaxel-d6
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Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T2197 |
10-Deacetylbaccatin III
10-脱乙酰巴卡丁 III,10-脱乙酰基巴卡丁III |
Others | Others |
10-Deacetylbaccatin-III 是一种紫杉醇类似物制剂的中间体,具有抗癌活性。 | |||
TN3251 |
7-Xylosyl-10-deacetylbaccatin III
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Others | Others |
7-Xylosyl-10-deacetylbaccatin III is a natural product from Taxus brevifolia. | |||
T83435 |
19-Hydroxy-10-deacetylbaccatin III
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19-Hydroxy-10-deacetylbaccatin III (compound 13) 是紫杉烷类化合物,显示出潜在的抗肿瘤作用。在 A498 和 NCI-H226 细胞系中,此化合物表现出轻微的细胞毒性效应。研究指出,当浓度为 30 μg/mL 时,19-Hydroxy-10-deacetylbaccatin III 对 A498 细胞和 NCI-H226 细胞的抑制率为 16.6% 和 32%。 | |||
T2543 |
Cabazitaxel
XRP6258,卡巴他塞,RPR-116258A,TXD 258,taxoid XRP6258 |
Microtubule Associated; Autophagy | Autophagy; Cytoskeletal Signaling |
Cabazitaxel (taxoid XRP6258) 是一种紫杉烷类的抗肿瘤剂,可用于治疗多西他赛失败后的去势抵抗性转移性前列腺癌。 |