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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T40580 17β-Estradiol sulfate sodium

17β-Estradiol 3-sulfate sodium

Antibiotic Microbiology/Virology
17β-Estradiol sulfate sodium (17β-Estradiol 3-sulfate sodium) 是一种神经活性雌激素,具有血管保护作用,可抑制巴西奈瑟菌的生长,破环水生生态系统。
T65147 Estradiol enanthate

Estradiol enanthate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65147,CAS号为 4956-37-0。
T72390 Estradiol hemihydrate

17β-Oestradiol hemihydrate,β-Estradiol hemihydrate ; 17β-Estradiol hemihydrate ; 17β-Oestradiol hemihydrate,17β-Estradiol hemihydrate,β-Estradiol hemihydrate

Estradiol (β-Estradiol) hemihydrate 是主要女性性激素的类固醇激素。它能上调人类子宫内膜干细胞 (hEnSCs) 的神经标志物表达,促进神经分化,适用于癌症、神经退行性疾病和神经组织工程研究。
T36917 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)

Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2 1.Hadd, H.E., Slikker, W., Jr., and Helton, E.D.The synthesis and characterization of the glucopyranosiduronic acids of 17a-ethynylestradiol-17bJ. Steroid Biochem.13(9)1107-1114(1980) 2.Griffith, D.R., Soule, M.C.K., Eglinton, T.I., et al.Steroidal estrogen sources in a sewage-impacted coastal oceanEnviron. Sci.: Proce...
T37004 Estradiol 3-sulfate 17β-Glucuronide (potassium salt)

Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most com...
T36807 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...
T36913 17-Epiestriol

17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme...
T60827 TPBM

TPBM 是雌激素受体 α (ERα)的有效抑制剂。TPBM 对 17β-雌二醇 (E2)-ERα 的IC50值为 9 μM。TPBM 对细胞无毒,可减少 E2·ERα 向内源性雌激素反应基因的募集。TPBM 抑制 ERα 阳性癌细胞的 E2 依赖性生长,IC 50 值为 5 μM。 TPBM 不影响非雌激素依赖性细胞生长。
T36039 16α-Hydroxyestrone

The naturally-occurring estrogens are estrone , estradiol , and estriol . 16α-hydroxy Estrone (16α-OHE1) is a hydroxylated metabolite of E1 as well as an interconversion product with E2. E1 is 16α-hydroxylated by cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A5, CYP3A4, and CYP3A7, with CYP3A5 being breast-specific. 16α-OHE1 is sulphatized or glucuronidated before excretion. It is increased in rheumatoid arthritis and decreased by physical activity. Unlike the parent estrogens and other ...

化合物

17β-Estradiol sulfate sodium
Cat.No: T40580
Synonym: 17β-Estradiol 3-sulfate sodium
Target: Antibiotic
Estradiol enanthate
Cat.No: T65147
Synonym:
Target:
Estradiol hemihydrate
Cat.No: T72390
Synonym: 17β-Oestradiol hemihydrate,β-Estradiol hemihydrate ; 17β-Estradiol hemihydrate ; 17β-Oestradiol hemihydrate,17β-Estradiol hemihydrate,β-Estradiol hemihydrate
Target:
Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)
Cat.No: T36917
Synonym:
Target:
Estradiol 3-sulfate 17β-Glucuronide (potassium salt)
Cat.No: T37004
Synonym:
Target:
Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
Cat.No: T36807
Synonym:
Target:
17-Epiestriol
Cat.No: T36913
Synonym:
Target:
TPBM
Cat.No: T60827
Synonym:
Target:
16α-Hydroxyestrone
Cat.No: T36039
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3378 Alpha-Estradiol

α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol

Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Alpha-Estradiol (Epiestradiol) 是一种雌性激素,可抑制5α-reductase,在雄原性脱发的研究中有潜力。

天然产物

Alpha-Estradiol
Cat.No: T3378
Synonym: α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol
Target: Estrogen/progestogen Receptor, Reductase, Endogenous Metabolite
TargetMol Loading
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