9
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40580 |
17β-Estradiol sulfate sodium
17β-Estradiol 3-sulfate sodium |
Antibiotic | Microbiology/Virology |
17β-Estradiol sulfate sodium (17β-Estradiol 3-sulfate sodium) 是一种神经活性雌激素,具有血管保护作用,可抑制巴西奈瑟菌的生长,破环水生生态系统。 | |||
T65147 |
Estradiol enanthate
|
||
Estradiol enanthate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65147,CAS号为 4956-37-0。 | |||
T72390 |
Estradiol hemihydrate
17β-Oestradiol hemihydrate,β-Estradiol hemihydrate ; 17β-Estradiol hemihydrate ; 17β-Oestradiol hemihydrate,17β-Estradiol hemihydrate,β-Estradiol hemihydrate |
||
Estradiol (β-Estradiol) hemihydrate 是主要女性性激素的类固醇激素。它能上调人类子宫内膜干细胞 (hEnSCs) 的神经标志物表达,促进神经分化,适用于癌症、神经退行性疾病和神经组织工程研究。 | |||
T36917 | Ethynyl Estradiol 3-β-D-Glucuronide (hydrate) | ||
Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2 1.Hadd, H.E., Slikker, W., Jr., and Helton, E.D.The synthesis and characterization of the glucopyranosiduronic acids of 17a-ethynylestradiol-17bJ. Steroid Biochem.13(9)1107-1114(1980) 2.Griffith, D.R., Soule, M.C.K., Eglinton, T.I., et al.Steroidal estrogen sources in a sewage-impacted coastal oceanEnviron. Sci.: Proce... | |||
T37004 |
Estradiol 3-sulfate 17β-Glucuronide (potassium salt)
|
||
Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most com... | |||
T36807 |
Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
|
||
Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ... | |||
T36913 |
17-Epiestriol
|
||
17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme... | |||
T60827 | TPBM | ||
TPBM 是雌激素受体 α (ERα)的有效抑制剂。TPBM 对 17β-雌二醇 (E2)-ERα 的IC50值为 9 μM。TPBM 对细胞无毒,可减少 E2·ERα 向内源性雌激素反应基因的募集。TPBM 抑制 ERα 阳性癌细胞的 E2 依赖性生长,IC 50 值为 5 μM。 TPBM 不影响非雌激素依赖性细胞生长。 | |||
T36039 | 16α-Hydroxyestrone | ||
The naturally-occurring estrogens are estrone , estradiol , and estriol . 16α-hydroxy Estrone (16α-OHE1) is a hydroxylated metabolite of E1 as well as an interconversion product with E2. E1 is 16α-hydroxylated by cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A5, CYP3A4, and CYP3A7, with CYP3A5 being breast-specific. 16α-OHE1 is sulphatized or glucuronidated before excretion. It is increased in rheumatoid arthritis and decreased by physical activity. Unlike the parent estrogens and other ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3378 |
Alpha-Estradiol
α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol |
Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Alpha-Estradiol (Epiestradiol) 是一种雌性激素,可抑制5α-reductase,在雄原性脱发的研究中有潜力。 |