T细胞是一种免疫系统中重要的白细胞类型,其在适应性免疫反应中起着核心作用。T细胞来源于骨髓中的造血干细胞。发育中的T细胞迁移到胸腺发育(或成熟)。迁移到胸腺后,前体细胞成熟为几种不同类型的T细胞。T 细胞在离开胸腺后也会继续分化。CD4 和 CD8 T 细胞在胸腺中被选择,但在外周进一步分化为具有不同功能的特化细胞。一组特定的分化T细胞亚型在控制和塑造免疫反应方面具有多种重要功能。其中一种功能是免疫介导的细胞死亡,它由两种主要亚型执行:CD8+“杀伤性”(细胞毒性)和CD4+“辅助性”T细胞。调节性T细胞是另一种独特的T细胞群,它们提供了耐受性的关键机制,免疫细胞能够将入侵细胞与“自身”区分开来。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPK-00544 | TLR3 Protein, Cynomolgus, Recombinant (His)
TLR3 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
TLR3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 78.04 kDa and the accession ... | |||
TMPK-00591 | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
|
Mouse | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s... | |||
TMPK-00642 | CD5 Protein, Rhesus macaque, Recombinant (His & Avi)
CD5 Protein, Rhesus macaque, Recombinant (His & Avi)
|
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ... | |||
TMPK-00643 | CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated
CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated
|
Rhesus | HEK293 Cells |
CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; ... | |||
TMPK-00653 | B7-2 Protein, Cynomolgus, Recombinant (His)
B7-2 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00688 | PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)
PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)
|
Canine | HEK293 Cells |
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp... | |||
TMPK-00694 | CD1A Protein, Human, Recombinant (His)
CD1A Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tai... | |||
TMPK-00716 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (aa 63-244)
|
Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s... | |||
TMPK-00717 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune s... | |||
TMPK-00860 | CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)
CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)
|
Mouse | HEK293 Cells |
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It b... | |||
TMPK-00880 | B7-2 Protein, Human, Recombinant (His & Avi)
B7-2 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00881 | B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-2 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00882 | B7-2 Protein, Human, Recombinant (hFc)
B7-2 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimul... | |||
TMPK-00955 | CD161 Protein, Human, Recombinant (His & Avi), Biotinylated
CD161 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leu... | |||
TMPK-00956 | CD161 Protein, Human, Recombinant (His)
CD161 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leu... | |||
TMPK-01135 | CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (His)
CD3 epsilon/CD3e Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cel... | |||
TMPK-01136 | CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
CD3 epsilon/CD3e Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
|
Cynomolgus | HEK293 Cells |
CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cel... | |||
TMPK-01176 | CD28 Protein, Canine, Recombinant (His)
CD28 Protein, Canine, Recombinant (His)
|
Canine | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-01177 | CD28 Protein, Canine, Recombinant (mFc)
CD28 Protein, Canine, Recombinant (mFc)
|
Canine | HEK293 Cells |
CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen present... | |||
TMPK-01230 | CLEC2D Protein, Human, Recombinant (hFc & Avi)
CLEC2D Protein, Human, Recombinant (hFc & Avi)
|
Human | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contra... |