keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) 是一种促甲状腺激素释放激素的生理代谢产物。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 182 | 现货 | ||
5 mg | ¥ 468 | 现货 | ||
10 mg | ¥ 756 | 现货 | ||
25 mg | ¥ 1,178 | 现货 | ||
50 mg | ¥ 1,590 | 现货 | ||
100 mg | ¥ 2,446 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 429 | 现货 |
产品描述 | Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) (TRH-OH) causes a variety of thyroidal and non-thyroidal effects, the best known being the feedback regulation of thyroid hormone levels. |
体外活性 | Thyrotropin-releasing-hormone (TRH) stimulated the release of newly synthesized GH and PRL, but not thyroid-stimulating hormone. In addition, TRH stimulated a dose-related increase in the release of newly synthesized GH and PRL at 10(-9) to 10(-7) M. Cyclo(His-Pro) stimulated the release of newly synthesized GH dose- dependently. TRH, cyclo(His-Pro), and hGHRH stimulated GH synthesis, while SRIF inhibited this at 10(-7) M. The release of newly synthesized PRL into culture medium was also stimulated by TRH and hGHRH, but inhibited by SRIF. PRL synthesis was not affected by TRH-OH and cyclo(His-Pro). Intracellular contents of GH and PRL in the pituitary did not change significantly.TRH plays an important role in both GH and PRL synthesis and release[1]. |
别名 | TRH-OH |
分子量 | 363.37 |
分子式 | C16H21N5O5 |
CAS No. | 24769-58-2 |
keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (30.27 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.752 mL | 13.7601 mL | 27.5202 mL | 68.8004 mL |
5 mM | 0.5504 mL | 2.752 mL | 5.504 mL | 13.7601 mL | |
10 mM | 0.2752 mL | 1.376 mL | 2.752 mL | 6.88 mL | |
20 mM | 0.1376 mL | 0.688 mL | 1.376 mL | 3.44 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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