keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cefodizime 是一种新型头孢菌素抗生素,具有广泛的生物活性。Cefodizime 对肾脏没有毒性且具有良好的耐受性和免疫调节活性,具有抗菌活性,可用于研究呼吸系统和泌尿系统的严重感染。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 257 | 现货 | ||
10 mg | ¥ 413 | 现货 | ||
25 mg | ¥ 560 | 现货 | ||
50 mg | ¥ 663 | 现货 | ||
100 mg | ¥ 913 | 现货 | ||
500 mg | ¥ 2,280 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 455 | 现货 |
产品描述 | Cefodizime is a new cephalosporin antibiotic with a wide range of biological activities.Cefodizime is non-toxic to the kidneys and is well tolerated with immunomodulatory activity.Cefodizime has antimicrobial activity and is used in the study of serious infections of the respiratory and urinary systems. |
体外活性 | Cefodizime displays modest yet variable inhibitory effects against Citrobacter species, including Citrobacter freundii, and Serratia marcescens. It also inhibits other Gram-negative bacteria, such as Haemophilus influenzae, Moraxella catarrhalis, Neisseria gonorrhoeae, and Neisseria meningitidis. Cefodizime is a bactericidal antibiotic with a strong affinity for penicillin-binding proteins 1A/B, 2, and 3 in E. coli. In vitro, the concentrations of Cefodizime required for bactericidal activity against susceptible strains of both Gram-positive and Gram-negative bacteria are generally comparable to the minimum inhibitory concentrations.[1] |
体内活性 | Cefodizime (50 mg/kg; S.C.; single; experimentally-induced K. pneumoniae respiratory tract infections in mice) exhibits activity comparable to Cefotaxime and Ceftazidime and surpassing that of Cefoperazone, Latamoxef, Cefuroxime, or cefazolin for the initial 8 hours. In contrast to these cephalosporins, Cefodizime maintains significant bactericidal activity for a duration of at least 48 hours after a single injection. Although Cefodizime can no longer be detected in the serum, it achieves complete bacterial clearance from the lungs within 48 hours in 50% of the mice.[1] |
分子量 | 584.67 |
分子式 | C20H20N6O7S4 |
CAS No. | 69739-16-8 |
keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11.69 mg/mL (20 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 1.7104 mL | 8.5518 mL | 17.1037 mL | 42.7592 mL |
5 mM | 0.3421 mL | 1.7104 mL | 3.4207 mL | 8.5518 mL | |
10 mM | 0.171 mL | 0.8552 mL | 1.7104 mL | 4.2759 mL | |
20 mM | 0.0855 mL | 0.4276 mL | 0.8552 mL | 2.138 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Cefodizime 69739-16-8 Microbiology/Virology Antibacterial Antibiotic Inhibitor inhibitor inhibit