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Cat. No. | Product Name | Target | Signaling Pathways |
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T1536 |
Promestriene
3-propyl ethyl,舒经劳,17B-methyl estradiol,Promestriano |
Estrogen/progestogen Receptor | Endocrinology/Hormones |
Promestriene (3-propyl ethyl) 是局部有效的雌激素,是合成的雌二醇二乙醚。它对阴道萎缩有作用,但吸收量小。 | |||
T0187 |
Amorolfine hydrochloride
Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002 |
Antibiotic; Antifungal | Microbiology/Virology |
Amorolfine hydrochloride (Amorolfine HCl) 是一种抗真菌剂。 | |||
T27322 |
Fispemifene
HM-101,HM 101,HM101 |
Others | Others |
Fispemifene (HM-101) 是一种雌激素受体调节剂(SERM),可用于治疗泌尿生殖系统综合征和阴道萎缩。 | |||
T1108 |
Nithiamide
Aminitrozole,醋胺硝唑,CL-5279 |
Antibacterial; Antibiotic | Microbiology/Virology |
Nithiamide (CL-5279) 是一种口服的抗原虫剂,用于治疗阴道滴虫病。它是非-5-硝基咪唑药物,可作兽用抗生素。 | |||
T0824 |
4-Nonylphenol polyethoxylate
Nonoxynol,Nonoxinol-9,壬苯醇醚 |
COX | Immunology/Inflammation; Neuroscience |
4-Nonylphenol polyethoxylate (Nonoxinol-9) 是一种表面活性剂,普遍用作避孕药中的杀精剂。 | |||
T28237 |
Onapristone
IVV-1001,ZK 98299,IVV 1001,ZK98299,ZK-98299,IVV1001 |
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Onapristone, a progesterone receptor antagonist, is used potentially for the treatment of breast cancer, advanced prostate cancer, and inducer of vaginal bleeding. | |||
T10795 |
Chlordantoin
Clodantoin,氯登妥因 |
Others | Others |
Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment. | |||
T25700 |
Levormeloxifene
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Levormeloxifene is a selective modulator of the estrogen receptor. It inhibits the production of vaginal tropoelastin and transforming growth factor-beta 1. | |||
T37435 | PACAP-related Peptide (rat) (trifluoroacetate salt) | PACAP | GPCR/G Protein |
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica... | |||
TMIH-0414 |
Ospemifene-d4
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Ospemifene-d4 是 Ospemifene 的氘代化合物。Ospemifene 的 CAS 号为 128607-22-7。Ospemifene 是非雌激素的选择性雌激素受体调节剂,能够作用于雌激素受体α (Kis:380 nM)和 Erβ (Kis:410 nM)。它可用于研究阴道萎缩乳腺癌。 | |||
T35701 |
FSL-1 TFA
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FSL-1 TFA, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection[1]. FSL-1 TFA induces MMP-9 production through TLR2 and NF-κB/AP-1 signaling pathways in monocytic THP-1 cells[2]. FSL-1 significantly reduces HSV-2 replication in human vaginal epithelial cells (EC)[1].FSL-1 induces significant resistance to experimental genital HSV-2 infection through elaboration of a specific cytokine response profile[1].FSL-1 (50 ng/mL, 24 hours) induce... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T4848 |
Mandelic acid
acidomandelico,DL-Mandelic acid,扁桃酸 |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
DL-Mandelic acid (acidomandelico) 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。 |