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11

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T1536 Promestriene

3-propyl ethyl,舒经劳,17B-methyl estradiol,Promestriano

Estrogen/progestogen Receptor Endocrinology/Hormones
Promestriene (3-propyl ethyl) 是局部有效的雌激素,是合成的雌二醇二乙醚。它对阴道萎缩有作用,但吸收量小。
T0187 Amorolfine hydrochloride

Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002

Antibiotic; Antifungal Microbiology/Virology
Amorolfine hydrochloride (Amorolfine HCl) 是一种抗真菌剂。
T27322 Fispemifene

HM-101,HM 101,HM101

Others Others
Fispemifene (HM-101) 是一种雌激素受体调节剂(SERM),可用于治疗泌尿生殖系统综合征和阴道萎缩。
T1108 Nithiamide

Aminitrozole,醋胺硝唑,CL-5279

Antibacterial; Antibiotic Microbiology/Virology
Nithiamide (CL-5279) 是一种口服的抗原虫剂,用于治疗阴道滴虫病。它是非-5-硝基咪唑药物,可作兽用抗生素。
T0824 4-Nonylphenol polyethoxylate

Nonoxynol,Nonoxinol-9,壬苯醇醚

COX Immunology/Inflammation; Neuroscience
4-Nonylphenol polyethoxylate (Nonoxinol-9) 是一种表面活性剂,普遍用作避孕药中的杀精剂。
T28237 Onapristone

IVV-1001,ZK 98299,IVV 1001,ZK98299,ZK-98299,IVV1001

Onapristone, a progesterone receptor antagonist, is used potentially for the treatment of breast cancer, advanced prostate cancer, and inducer of vaginal bleeding.
T10795 Chlordantoin

Clodantoin,氯登妥因

Others Others
Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment.
T25700 Levormeloxifene

Levormeloxifene is a selective modulator of the estrogen receptor. It inhibits the production of vaginal tropoelastin and transforming growth factor-beta 1.
T37435 PACAP-related Peptide (rat) (trifluoroacetate salt)

PACAP GPCR/G Protein
PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adenylate cyclase-activating polypeptide . It is expressed in rat hypothalamus as well as within the nerves of the median eminence, the anterior pituitary, bed nucleus of the stria terminalis, cerebellum, cerebral cortex, and amygdala. PRP is also expressed in vaginal, uterine cervica...
TMIH-0414 Ospemifene-d4

Ospemifene-d4 是 Ospemifene 的氘代化合物。Ospemifene 的 CAS 号为 128607-22-7。Ospemifene 是非雌激素的选择性雌激素受体调节剂,能够作用于雌激素受体α (Kis:380 nM)和 Erβ (Kis:410 nM)。它可用于研究阴道萎缩乳腺癌。
T35701 FSL-1 TFA

FSL-1 TFA, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection[1]. FSL-1 TFA induces MMP-9 production through TLR2 and NF-κB/AP-1 signaling pathways in monocytic THP-1 cells[2]. FSL-1 significantly reduces HSV-2 replication in human vaginal epithelial cells (EC)[1].FSL-1 induces significant resistance to experimental genital HSV-2 infection through elaboration of a specific cytokine response profile[1].FSL-1 (50 ng/mL, 24 hours) induce...

化合物

Promestriene
Cat.No: T1536
Synonym: 3-propyl ethyl,舒经劳,17B-methyl estradiol,Promestriano
Target: Estrogen/progestogen Receptor
Amorolfine hydrochloride
Cat.No: T0187
Synonym: Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002
Target: Antibiotic, Antifungal
Fispemifene
Cat.No: T27322
Synonym: HM-101,HM 101,HM101
Target: Others
Nithiamide
Cat.No: T1108
Synonym: Aminitrozole,醋胺硝唑,CL-5279
Target: Antibacterial, Antibiotic
4-Nonylphenol polyethoxylate
Cat.No: T0824
Synonym: Nonoxynol,Nonoxinol-9,壬苯醇醚
Target: COX
Onapristone
Cat.No: T28237
Synonym: IVV-1001,ZK 98299,IVV 1001,ZK98299,ZK-98299,IVV1001
Target:
Chlordantoin
Cat.No: T10795
Synonym: Clodantoin,氯登妥因
Target: Others
Levormeloxifene
Cat.No: T25700
Synonym:
Target:
PACAP-related Peptide (rat) (trifluoroacetate salt)
Cat.No: T37435
Synonym:
Target: PACAP
Ospemifene-d4
Cat.No: TMIH-0414
Synonym:
Target:
FSL-1 TFA
Cat.No: T35701
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4848 Mandelic acid

acidomandelico,DL-Mandelic acid,扁桃酸

Others; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others
DL-Mandelic acid (acidomandelico) 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。

天然产物

Mandelic acid
Cat.No: T4848
Synonym: acidomandelico,DL-Mandelic acid,扁桃酸
Target: Others, Endogenous Metabolite, Antibacterial
TargetMol Loading
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