Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2712 |
Nifekalant hydrochloride
|
Potassium Channel | Membrane transporter/Ion channel |
Nifekalant hydrochloride 是一种 IKr 钾通道阻滞剂,IC50为10 µM,属于 III 类抗心律不齐化合物,可用于快速室上性心律失常的研究。 | |||
T7811 |
Pilsicainide HCl
SUN 1165,盐酸吡西卡呢 |
Sodium Channel | Membrane transporter/Ion channel |
Pilsicainide HCl (SUN 1165) 是一种纯钠通道阻滞剂。 | |||
T7219 |
Flecainide acetate
Flecainide (acetate),氟卡胺,R-818,醋酸洗必太 |
Sodium Channel | Membrane transporter/Ion channel |
Flecainide acetate (R-818) 是位于心脏的 Nav1.5钠离子通道的阻断剂,具有抗心律失常的作用。 | |||
T71228 | Adaprolol maleate | ||
Adaprolol maleate is a beta-blocker and opthalmic which may be used in the treatment of Glaucoma or other ailments of the eye. Adaprolol has marked electrophysiologic effects. Its major action was on sinus node; it prolonged the basic sinus cycle length and had significant effect on intrinsic automaticity as reflected by the prolonged corrected sinus node recovery time and sinuatrial conduction time. There was, also, direct effect on atrial function and AV nodal function. Adaprolol prolonged the... |