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21

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19309L1	Endothelin 1 (swine, human) acetate Endothelin 1 (swine, human) acetate(117399-94-7 free base)	Endothelin Receptor	GPCR/G Protein
	Endothelin 1 (swine, human) acetate(117399-94-7 free base) 是一种合成肽，其序列为人和猪内皮素 1。它是一种有效的内源性血管收缩剂，通过两种类型的受体 ETA 和 ETB 起作用。
T19309	Endothelin 1 (swine, human)	Others	Others
	Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB.
T81182	Secretin (swine)
	Secretin (swine)为源自猪的神经内分泌激素，由十二指肠黏膜S细胞产生，具有27个氨基酸的多肽结构，并针对分泌素受体起作用。此激素在各类成熟肠内分泌细胞亚群中表达，受脂肪酸的促进。它主要激发胰腺释放水和碳酸氢盐，同时在消化系统、中枢神经系统和能量代谢方面具有广泛应用。
T80081	Insulin (swine)
	Insulin(swine)，即源自猪的胰岛素，应用于糖尿病研究领域。
T81553	Pancreastatin (swine)
	Pancreastatin (swine)为含49个氨基酸残基的多肽，强效抑制葡萄糖刺激之胰岛素释放，可自猪胰腺分离鉴定。
T76328	Oxyntomodulin (swine)
	Oxyntomodulin (swine) 是一种肽类激素，在餐后状态下从肠道释放，作为GLP-1R(GLP-1 受体) 和GCGR(胰高血糖素受体) 的双重激动剂，能够抑制食欲并减少食物摄入。
T80694	β-Corticotropin (swine)
	β-Corticotropin (swine) 为ACTH（肽激素促肾上腺皮质激素）的合成品，具有刺激类固醇释放的功能。
T75731	Endothelin 1 (swine, human) (TFA)
	Endothelin 1 (swine, human) (TFA) 是具有人和猪内皮素 1 序列的合成肽，是有效的内源性血管收缩剂。Endothelin 1 通过两种类型受体 ETA 和 ETB 发挥作用。
T1647	Ronidazole 洛硝哒唑,Ronidazol,罗硝唑,Ridzol	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ronidazole (Ronidazol) 是一种口服有效的抗原虫和抗菌试剂。它在猫模型中对胎儿三毛滴虫有效，还可研究组织口癣和猪痢疾。
T4267	Tulathromycin A CP 472295,Draxxin,Tulathromycin,托拉菌素 A	Antibacterial; Antibiotic	Microbiology/Virology
	Tulathromycin A (CP 472295) 是一种大环内酯类抗生素，靶向细菌核糖体抑制蛋白质合成 (IC50=0.26 µM)，具有免疫调节作用。它可研究牛和猪的呼吸道疾病。
T76081	Endothelin 1 (swine, human), Alexa Fluor 488-labeled
	Endothelin 1 (swine, human), Alexa Fluor 488-labeled 是标记了488 荧光的 Endothelin 1 合成肽。Endothelin 1 (swine, human) 是具有人和猪内皮素 1 序列的合成肽，是有效的内源性血管收缩剂。Endothelin 1 通过两种类型受体 ETA 和 ETB 发挥作用。
T0770	Carbadox Getroxel,卡巴多,Mecadox	Antibacterial; Antibiotic	Microbiology/Virology
	Carbadox (Mecadox) 是一种喹喔啉二氧化氮抗生素，用于育龄期的猪，治疗猪痢疾和肠炎，促进成长。
T40612	Manganese(salen) chloride EUK-8	Others	Others
	Manganese(salen) chloride (EUK-8) 是超氧化物歧化酶和过氧化氢酶的一种模拟物，具有氧自由基清除性能。它可减轻内毒素血症猪的急性肺损伤。
T37514	Hydroxy Dimetridazole	Drug Metabolite	Metabolism
	Hydroxy Dimetridazole 是Dimetridazol 的羟基化代谢产物。Dimetridazol 是一种硝基咪唑类药物，可用于对抗原生动物感染。
T24777	Sedecamycin T-2636A,T-2636,Ro 23-0731/000,NSC 145117
	Sedecamycin is a 17-membered macrolide antibiotic. It is used for treating swine dysentery.
T24318	L 665871 L-665,871,L-665871,L665,871,L665871,L 665,871
	L 665871 is used as a beta-agonist. It works as a potential swine growth promoter.
T24277	Hydroxy ipronidazole L-12407,Ipronidazole-OH,L12407,L 12407
	L 12407 is an antiprotozoal drug of the nitroimidazole class. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.
T37849	Butafosfan
	Butafosfan is an organic phosphorus supplement that is given, most commonly with cyanocobalamin, to cattle, swine, horses, and poultry for the prevention or treatment of deficiencies. When given with cyanocobalamin, butafosfan alters lipid metabolism, serving to decrease the prevalence of subclinical ketosis.
T40573	Hydroxymetronidazole Hydroxymetronidazole,Metronidazole-OH
	Hydroxymetronidazole (Metronidazole-OH) is a nitroimidazole compound that functions as a metabolite of Metronidazole. It is commonly employed in poultry research to investigate bacterial and protozoal diseases, as well as in the study of swine dysentery and genital trichomoniasis in cattle.
T37231	(+)-Cloprostenol methyl ester
	(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprosteno...
T37230	(+)-5-trans Cloprostenol
	Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of (+)-cloprostenol. The (+)-5-trans isomer is 20-fold less active than the 5-cis form in terminating pregnancy in the hamster.

化合物

Endothelin 1 (swine, human) acetate

Cat.No: T19309L1

Synonym: Endothelin 1 (swine, human) acetate(117399-94-7 free base)

Target: Endothelin Receptor

Endothelin 1 (swine, human)

Cat.No: T19309

Target: Others

Secretin (swine)

Cat.No: T81182

Insulin (swine)

Cat.No: T80081

Pancreastatin (swine)

Cat.No: T81553

Oxyntomodulin (swine)

Cat.No: T76328

β-Corticotropin (swine)

Cat.No: T80694

Endothelin 1 (swine, human) (TFA)

Cat.No: T75731

Cat.No: T1647

Synonym: 洛硝哒唑,Ronidazol,罗硝唑,Ridzol

Target: Antibacterial, Antibiotic, Parasite

Tulathromycin A

Cat.No: T4267

Synonym: CP 472295,Draxxin,Tulathromycin,托拉菌素 A

Target: Antibacterial, Antibiotic

Endothelin 1 (swine, human), Alexa Fluor 488-labeled

Cat.No: T76081

Cat.No: T0770

Synonym: Getroxel,卡巴多,Mecadox

Target: Antibacterial, Antibiotic

Manganese(salen) chloride

Cat.No: T40612

Synonym: EUK-8

Target: Others

Hydroxy Dimetridazole

Cat.No: T37514

Target: Drug Metabolite

Cat.No: T24777

Synonym: T-2636A,T-2636,Ro 23-0731/000,NSC 145117

Cat.No: T24318

Synonym: L-665,871,L-665871,L665,871,L665871,L 665,871

Hydroxy ipronidazole

Cat.No: T24277

Synonym: L-12407,Ipronidazole-OH,L12407,L 12407

Cat.No: T37849

Hydroxymetronidazole

Cat.No: T40573

Synonym: Hydroxymetronidazole,Metronidazole-OH

(+)-Cloprostenol methyl ester

Cat.No: T37231

(+)-5-trans Cloprostenol

Cat.No: T37230

Cat. No.	Product Name	Target	Signaling Pathways
T8065	Tiamulin Thiamutilin,泰妙菌素	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Tiamulin (Thiamutilin) 是一类二萜，广泛用于控制猪的传染疾病，包括猪痢疾和地方性肺炎等。
T4S1422	Praeruptorin E 白花前胡素 E,白花前胡素E	Others; Calcium Channel	Membrane transporter/Ion channel; Metabolism; Others
	Praeruptorin E 是白花前胡中的一种主要成分，是钙拮抗剂，pD2′值为 5.2。
T25457	Glyceryl monolinoleate Emalsy MU,Linolein, mono-,Sunsoft 8090,Rikemal MU 100
	Glyceryl monolinoleate can inactivate or inhibit African Swine Fever virus.

天然产物

Cat.No: T8065

Synonym: Thiamutilin,泰妙菌素

Target: Others, Antibacterial, Antibiotic

Cat.No: T4S1422

Synonym: 白花前胡素 E,白花前胡素E

Target: Others, Calcium Channel

Glyceryl monolinoleate

Cat.No: T25457

Synonym: Emalsy MU,Linolein, mono-,Sunsoft 8090,Rikemal MU 100

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