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44

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22434	Super-TDU	Others	Others
	Super-TDU, an inhibitory peptide, targets YAP-TEADs interaction.
TD0025	Super Fluor 647
	Super Fluor 647 dye is a bright, far-red–fluorescent dye with excitation ideally suited for the 594 nm or 633 nm laser lines. For stable signal generation in imaging and flow cytometry, Super Fluor 647 dye is pH-insensitive over a wide molar range.Probes
TP1569	Super-TDU (TFA) (1599441-71-0 free base) Super-TDU (TFA)
	uper-TDU is an inhibitory peptide targeting YAP-TEADs interaction.
TD0029	Super Fluor 750
	Super Fluor 750 dye is a bright, near-IR–fluorescent dye with excitation ideally suited for the 633 nm laser line or dye-pumped laser excitation. Super Fluor 750 dye is pH-insensitive over a wide molar range, helping ensure that you get stable signals in
TD0021	Super Fluor 488
	Super Fluor 488 dye is a bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line. For stable signal generation in imaging and flow cytometry, Super Fluor 488 dye is pH-insensitive over a wide molar range.Probes with high fluo
TD0023	Super Fluor 555
	Probes with high fluorescence quantum yield and high photostability allow detection of low-abundance biological structures with great sensitivity. Super Fluor 555 dye molecules can be attached to proteins at high molar ratios without significant self-quen
TD0027	Super Fluor 680
	Super Fluor 680 dye is a bright, near-IR fluorescent dye with excitation ideally suited for the 633 nm laser line. For stable signal generation in imaging and flow cytometry, Super Fluor 680 dye is pH-insensitive over a wide molar range.The fluorescence q
TD0024	Super Fluor 555, SE
	This Super Fluor 555, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection. Super Fluor 555 dye molecules can be attached to proteins at high molar rat
TD0026	Super Fluor 647, SE	Others	Others
	Super Fluor 647, SE 是一种用于标记抗体、肽、蛋白质、示踪物和扩增底物的活性染料，可优化细胞标记和检测。Super Fluor 647, SE 染料分子可以以高摩尔比附着到蛋白质上，而无需显著的自猝灭，从而实现更明亮的共轭和更灵敏的检测。
TD0080	Super Texas Red,SE
	Texas Red is a Red fluorescent dye, purple-red powder, more stable.Texas Red is also a derivative of Rhodamine, which also includes Rhodamine red-x (RRX), TRITC, etc.As a Red dye, Texas Red can be used in the histochemical staining of cell samples, which
TD0028	Super Fluor 680, SE
	This Super Fluor 680, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection.
TD0030	Super Fluor 750, SE
	This Super Fluor 750, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection.
TD0022	Super Fluor 488, SE
	This Super Fluor 488, SE is a reactive dye for the labeling of antibodies, peptides, proteins, tracers, and amplification substrates optimized for cellular labeling and detection. Super Fluor 488 dye molecules can be attached to proteins at high molar rat
TP1331	Super-TDU (1-31) TFA
	Super-tdu (1-31) TFA is an endogenous ligand of heptapeptide receptor and has a strong anti-analgesic effect.
TP1383	Super-TDU 1-31
	Super-TDU (1-31) is a peptide of Super-TDU, which is an inhibitor of YAP-TEADs, shows potent anti-tumor activity.
TD0005	SYBR GREEN II SUPER Green II RNA gel stain 10,000× concentrate in DMSO (Electrophoresis Grade),SUPER Green II （效果同SYBR Green II）RNA染料（10,000× DMSO溶液）（电泳级）
	1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-to-noise ratio: the sample fluorescence signal is strong, while the background signal is low. 4) Simple operation: like EB, the dye does not degrade in the prefabricated gel and electrophoresis process;The dyeing process after electrophoresis takes only 30 minutes without decolor...
T76004	Super-TDU TFA
	Super-TDU TFA 是一种特异性的 YAP 拮抗剂，可以靶向 YAP-TEAD 相互作用。Super-TDU TFA 可以抑制胃癌小鼠模型的肿瘤生长。
T76005	Super-TDU (1-31)
	Super-TDU (1-31) 是 Super-TDU 的肽片段。Super-TDU (1-31) 是 YAP-TEAD 复合物的抑制剂。Super-TDU 在胃癌小鼠模型中显示出有效的抗肿瘤活性并抑制肿瘤生长。
T20594	Flamprop-methyl WL-29761,Suffix plus,WL 29761,WL29761,Super-Suffix,Lancer
	Flamprop-methyl is a post-emergence herbicide, it is usually used on wild oats.
T76005L	Super-TDU (1-31) (TFA)
	Super-TDU (1-31) TFA 是 Super-TDU 的肽片段。Super-TDU (1-31) TFA 是YAP-TEAD 复合物的抑制剂。Super-TDU TFA 在胃癌小鼠模型中显示出有效的抗肿瘤活性并抑制肿瘤生长。
T1814	ICILIN AG-3-5	TRP/TRPV Channel	Membrane transporter/Ion channel
	ICILIN (AG-3-5) 是一种有效的的瞬时受体电位 M8 (TRPM8) 离子通道激动剂。 Icilin 激活 EGTA 中的 TRPM8，该激活作用具有剂量依赖性， EC50=1.4 μM。Icilin 通过调节 T 细胞反应减轻自身免疫性神经炎症。
TD0001	SYBR GREEN 1 SUPER Green I （效果同SYBR Green I）核酸染料（10,000× DMSO溶液）（电泳级）,SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO,SYBRGREENⅠ核苷酸胶体染料	Others	Others
	SYBR GREEN 1 是一种不对称花青染料，用于检测核酸。它由一个 N-烷基化的苯并噻唑或苯并恶唑环系统组成，通过一甲基桥连接到吡啶鎓或喹啉鎓环系统。 SYBR Green I 与 dsDNA 的小沟结合，在 480 nm 波长处被激发。它具有 520 nm 的峰值荧光发射。
T78346	Superoxide dismutase SOD
	超氧化物歧化酶(SOD)是能清除超氧阴离子的抗氧化酶，它将自由基转化为氧气和过氧化氢，防止过氧亚硝酸盐的形成和进一步损伤。该酶在抗炎、抗肿瘤、辐射防护及抗衰老领域有着广泛应用和研究。
T78082	Supercinnamaldehyde
	Supercinnamaldehyde是一种有效的瞬时受体电位锚蛋白1(TRPA1)激活剂，具有0.8 μM的EC50值。它通过对半胱氨酸的共价修饰作用来激活TRPA1离子通道。
T26760	Bedoradrine sulfate KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Bedoradrine sulfate（MN-221 sulfate）是一种超选择性β2激动剂，可用于治疗哮喘加重和慢性阻塞性肺病。
TP2323L	Deslorelin acetate(57773-65-6 free base) Deslorelin acetate	GNRH Receptor	GPCR/G Protein
	Deslorelin acetate(57773-65-6 free base) 是一种促性腺激素释放激素超级激动剂(GnRH agonist)
T16867	SEC inhibitor KL-1 KL-1	Others	Others
	SEC inhibitor KL-1 (KL-1) 是一种拟肽先导化合物，是一种有效的选择性SEC 抑制剂，能够剂量依赖性地抑制 AFF4-CCNT1 相互作用。它能够破坏 SEC 支架蛋白 AFF4 和 P-TEFb 之间的相互作用，导致 Pol II 从启动子近端暂停位点的释放受损，并且进行性转录延伸的平均速率降低。
T16868	SEC inhibitor KL-2 KL-2	Others	Others
	SEC inhibitor KL-2 (KL-2) (KL-2) 是一种拟肽先导化合物，有效的选择性 SEC 抑制剂，通过破坏 SEC 支架蛋白 AFF4 和 P-TEFb 之间的相互作用，导致 Pol II 从启动子近端暂停位点的释放受损并且进行性转录延伸的平均速率降低。SEC inhibitor KL-2 剂量依赖性地抑制 AFF4-CCNT1 相互作用，Ki 值为 1.50 μM。
TNU0613	S-2-(4-aminobenzyl)-diethylenetriamine penta-t-butyl acetate
	Super-chelating agent& MRI contrast agent
T29467	610CP Carbopyronine 610CP,610-CP,610 CP
	610CP is a fluorescent probe for near-IR live-cell super-resolution imaging.
T29469	680SIR 680-SIR,Si-rhodamine 680SiR,680 SIR
	680SIR is a fluorescent probe for near-IR live-cell super-resolution imaging.
TNU0612	S-2-(4-Aminobenzyl)-diethylenetriamine pentaacetic acid TFA salt, p-NH2-Bn-DTPA-TFA
	Super-chelating agent & MRI contrast agent
T39504	PA Janelia Fluor® 646, SE PA-JF646-NHS
	PA Janelia Fluor 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag and SNAP-tag . PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ Excitation/emission ~650/664 nm).
T39128	Pro-Phe-Phe
	Pro-Phe-Phe, a highly aggregation-prone tripeptide composed of natural amino acids, exhibits the formation of distinctive helical-like sheets that engage in aromatic dry interfaces. This property makes Pro-Phe-Phe an excellent candidate for the development of modular super-helical self-assembling nanostructures.
T37470	Bismuth subcarbonate
	Bismuth subcarbonate, also known as bismuth carbonate oxide, is a versatile semiconductor compound based on bismuth, commonly utilized for its antibacterial properties, as well as in various applications such as sensors, super capacitors, and photocatalysts. Additionally, bismuth subcarbonate serves as a protective agent against gastric acid erosion, particularly in the treatment of gastric ulcers[1][2].
T41197	Phalloidin-Janelia Fluor®646 Phalloidin-Janelia Fluor®646,Phalloidin-JF646
	Phalloidin-Janelia Fluor®646 is a red fluorescent F-actin probe. Phalloidin-Janelia Fluor®646 is composed of the F-actin probe, Phalloidin, conjugated to Janelia Fluor®646. It is suitable for use in confocal and super-resolution microscopy techniques such as dSTORM. Excitation/emission maximum λ = 646/664 nm.
T11007	Desmethyl Levofloxacin	Others	Others
	Desmethyl Levofloxacin is a metabolite of levofloxacin. Levofloxacin is a synthetic fluoroquinolone drug, an antibacterial agent that can inhibit the super-coiling activity of bacterial DNA gyrase and prevent DNA replication.
T39586	Cantrixil TRX-E-002-1
	Cantrixil (TRX-E-002-1) is a second-generation super-benzopyran (SBP) compound, derived from TRX-E-002. It elicits an increase in phosphorylated c-Jun levels, leading to caspase-mediated apoptosis in ovarian cancer cells. Cantrixil exhibits potent pan anti-cancer activity against various cancer phenotypes.
T39800	S2116
	S2116 is a powerful inhibitor of lysine-specific demethylase 1 (LSD1), and it is a derivative of N-alkylated tranylcypromine (TCP). S2116 exhibits its inhibitory effects by increasing H3K9 methylation and inducing reciprocal H3K27 deacetylation at super-enhancer regions. In TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells, S2116 triggers apoptosis by repressing the transcription of NOTCH3 and TAL1 genes. Furthermore, S2116 demonstrates significant growth retardation of T-ALL cells...
T61911	Antibacterial agent 98
	Antibacterial agent 98 (compound g37) 是口服有效的抗菌剂，可以抑制 Gyrase B 的 ATP 酶活性并削弱金黄色葡萄球菌 (S. aureus )的DNA 超螺旋。Antibacterial agent 98 不会诱导 MRSA (耐甲氧西林金黄色葡萄球菌 (S. aureus)) 的耐药性发展。
T39799	S2157 S2157
	S2157, a potent N-alkylated tranylcypromine (TCP) derivative lysine-specific demethylase 1 (LSD1) inhibitor, enhances H3K9 methylation and concurrently reduces H3K27 acetylation at super-enhancer sites. This compound triggers apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by inhibiting NOTCH3 and TAL1 gene expression. Moreover, S2157 is capable of crossing the blood-brain barrier, effectively eliminating central nervous system (CNS) leukemia in mice models implanted...
T83755	ssK36 TFA
	ssK36是一种针对组蛋白甲基转移酶SET结构域含蛋白2 (SETD2) 的肽类超级底物，其对应于组蛋白H3赖氨酸36 (H3K36) 的第29至43个氨基酸，且在第31、32、36、37和39位氨基酸上发生了置换。在无细胞检测中，ssK36的甲基化程度比H3K36 (29-43) 高70倍，速度快290倍。
T82729	Chol-N3
	Chol-N3是一种chol基探针，具备生物正交反应特性。它配合SRM技术能够在静息活细胞表面实现纳米级脂质异质性的直接可视化。Chol-N3作为点击化学试剂，其Azide基团可参与铜催化的叠氮-炔环加成反应（CuAAc），并且能与含DBCO或BCN基团的分子进行菌株促进的炔-叠氮环加成反应（SPAAC）。
T31300	Decan-2-ol 2-Hydroxydecane,EINECS 214-296-6,AI3-11545,NSC 67349
	Decan-2-ol is used to study the substrate spectrum of phytanoyl-CoA hydroxylase with regard to the length of both the acyl chain and the branch at position. It is used to develop a miniature catalytic reactor for the oxidation of alcohols with O2 in super

化合物

Cat.No: T22434

Target: Others

Super Fluor 647

Cat.No: TD0025

Super-TDU (TFA) (1599441-71-0 free base)

Cat.No: TP1569

Synonym: Super-TDU (TFA)

Super Fluor 750

Cat.No: TD0029

Super Fluor 488

Cat.No: TD0021

Super Fluor 555

Cat.No: TD0023

Super Fluor 680

Cat.No: TD0027

Super Fluor 555, SE

Cat.No: TD0024

Super Fluor 647, SE

Cat.No: TD0026

Target: Others

Super Texas Red,SE

Cat.No: TD0080

Super Fluor 680, SE

Cat.No: TD0028

Super Fluor 750, SE

Cat.No: TD0030

Super Fluor 488, SE

Cat.No: TD0022

Super-TDU (1-31) TFA

Cat.No: TP1331

Super-TDU 1-31

Cat.No: TP1383

Cat.No: TD0005

Synonym: SUPER Green II RNA gel stain *10,000× concentrate in DMSO* (Electrophoresis Grade),SUPER Green II （效果同SYBR Green II）RNA染料（10,000× DMSO溶液）（电泳级）

Super-TDU TFA

Cat.No: T76004

Super-TDU (1-31)

Cat.No: T76005

Flamprop-methyl

Cat.No: T20594

Synonym: WL-29761,Suffix plus,WL 29761,WL29761,Super-Suffix,Lancer

Super-TDU (1-31) (TFA)

Cat.No: T76005L

Cat.No: T1814

Synonym: AG-3-5

Target: TRP/TRPV Channel

Cat.No: TD0001

Synonym: SUPER Green I （效果同SYBR Green I）核酸染料（10,000× DMSO溶液）（电泳级）,SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO,SYBRGREENⅠ核苷酸胶体染料

Target: Others

Superoxide dismutase

Cat.No: T78346

Synonym: SOD

Supercinnamaldehyde

Cat.No: T78082

Bedoradrine sulfate

Cat.No: T26760

Synonym: KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246

Target: Adrenergic Receptor

Deslorelin acetate(57773-65-6 free base)

Cat.No: TP2323L

Synonym: Deslorelin acetate

Target: GNRH Receptor

SEC inhibitor KL-1

Cat.No: T16867

Synonym: KL-1

Target: Others

SEC inhibitor KL-2

Cat.No: T16868

Synonym: KL-2

Target: Others

S-2-(4-aminobenzyl)-diethylenetriamine penta-t-butyl acetate

Cat.No: TNU0613

Cat.No: T29467

Synonym: Carbopyronine 610CP,610-CP,610 CP

Cat.No: T29469

Synonym: 680-SIR,Si-rhodamine 680SiR,680 SIR

S-2-(4-Aminobenzyl)-diethylenetriamine pentaacetic acid TFA salt, p-NH2-Bn-DTPA-TFA

Cat.No: TNU0612

PA Janelia Fluor® 646, SE

Cat.No: T39504

Synonym: PA-JF646-NHS

Cat.No: T39128

Bismuth subcarbonate

Cat.No: T37470

Phalloidin-Janelia Fluor®646

Cat.No: T41197

Synonym: Phalloidin-Janelia Fluor®646,Phalloidin-JF646

Desmethyl Levofloxacin

Cat.No: T11007

Target: Others

Cat.No: T39586

Synonym: TRX-E-002-1

Cat.No: T39800

Antibacterial agent 98

Cat.No: T61911

Cat.No: T39799

Synonym: S2157

Cat.No: T83755

Cat.No: T82729

Cat.No: T31300

Synonym: 2-Hydroxydecane,EINECS 214-296-6,AI3-11545,NSC 67349

Cat. No.	Product Name	Target	Signaling Pathways
T75636	(E/Z)-Squalene (E/Z)-Super Squalene,(E/Z)-AddaVax
	(E/Z)-Squalen 调节细胞内活性氧化物质 (ROS) 的产生，并呈浓度和时间依赖性引起细胞凋亡和坏死。(E/Z)-Squalene ((E/Z)-AddaVax) 在肝脏中积累并降低肝脏胆固醇和甘油三酯。
T4749	Squalene 角鲨烯,Nikko Squalane EX,Super Squalene,AddaVax,all-trans-Squalene,trans-Squalene,Spinacene	Reactive Oxygen Species; Endogenous Metabolite; Antifungal	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Squalene (AddaVax) 是胆固醇合成的中间产物，具有降血脂、保肝、心脏保护、抗氧化和抗毒活性等多种药理特性。它还具有抗真菌活性，可用于毛癣菌治疗的相关研究。
TN4711	Onitin	Others	Others
	Onitin shows super-oxide and DPPH free radical scavenging effects.It also exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.

天然产物

Cat.No: T75636

Synonym: (E/Z)-Super Squalene,(E/Z)-AddaVax

Cat.No: T4749

Synonym: 角鲨烯,Nikko Squalane EX,Super Squalene,AddaVax,all-trans-Squalene,trans-Squalene,Spinacene

Target: Reactive Oxygen Species, Endogenous Metabolite, Antifungal

Cat.No: TN4711

Target: Others

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