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Search Results for " squalene epoxidase "

11

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1497	Liranaftate Piritetrate,利拉萘酯,M-732	Antifungal	Microbiology/Virology
	Liranaftate (Piritetrate) 是一种具有抗真菌活性的硫代氨基甲酸酯和角鲨烯环氧酶抑制剂，可研究皮肤癣菌。
T11321	FR194738 free base	Antifungal	Microbiology/Virology
	FR194738 free base 抑制 HepG2 细胞匀浆中的角鲨烯环氧酶活性，IC50 为 9.8 nM。
TQ0115	NB-598	Antifungal	Microbiology/Virology
	NB-598 是一种鲨烯环氧化酶竞争性抑制剂，可以阻碍甘油三酯的生物合成。
T1217	Butenafine hydrochloride KP363 (Hydrochloride),Butenafine HCl,KP-363,盐酸布替萘芬	Antibiotic; Antifungal	Microbiology/Virology
	Butenafine hydrochloride (KP363 Hydrochloride) 通过抑制鲨烯环氧酶阻断甾醇的合成，具有抗真菌活性。
T1543	Naftifine hydrochloride Naftifungin,盐酸萘替芬,Naftifine HCl,Naftin,Exoderil	Hedgehog/Smoothened; Antibiotic; Antifungal	GPCR/G Protein; Microbiology/Virology; Stem Cells
	Naftifine hydrochloride (Naftifine HCl) 是一种抗生素。它具有抗真菌活性，对皮肤真菌、曲霉、Sporothrix schenckii、假丝酵母属的酵母有抑制作用。
T83658	SQLE-IN-1	Antifungal	Microbiology/Virology
	SQLE-IN-1 是一种角鲨烯环氧化酶 (SQLE) 抑制剂，具有抗肿瘤活性，可抑制肝癌细胞系 Huh7 的增殖和迁移能力，抑制细胞胆固醇的生成，增加抑癌基因PTEN的表达，抑制PI3K和AKT的蛋白表达。
T12199	NB-598 Maleate	Others	Others
	NB-598 Maleate is a competitive squalene epoxidase (SE) inhibitor.
T12199L	NB-598 hydrochloride	Antifungal	Microbiology/Virology
	NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor.
T6702L	Terbinafine lactate DRG-0286,Terbinafine hydrochloride,Lamisil Krem,SF 86-327 hydrochloride,Lamisil,Lamisil AT
	Terbinafine, a synthetic allylamine antifungal, inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway.
T21365	Butenafine KP363,KP 363,Mentax,KP-363,Butop
	Butenafine hydrochloride is a hydrochloride of butenafine, which inhibits squalene epoxidase to inhibit the synthesis of ergosterol, leading to the increased permeability of the cell membranes, allowing their contents to leak out.
T11320	FR194738	Antifungal	Microbiology/Virology
	FR194738 是一种角鲨烯环氧酶抑制剂，在 HepG2 细胞匀浆中的 IC50 为 9.8 nM。

化合物

Cat.No: T1497

Synonym: Piritetrate,利拉萘酯,M-732

Target: Antifungal

FR194738 free base

Cat.No: T11321

Target: Antifungal

Cat.No: TQ0115

Target: Antifungal

Butenafine hydrochloride

Cat.No: T1217

Synonym: KP363 (Hydrochloride),Butenafine HCl,KP-363,盐酸布替萘芬

Target: Antibiotic, Antifungal

Naftifine hydrochloride

Cat.No: T1543

Synonym: Naftifungin,盐酸萘替芬,Naftifine HCl,Naftin,Exoderil

Target: Hedgehog/Smoothened, Antibiotic, Antifungal

Cat.No: T83658

Target: Antifungal

Cat.No: T12199

Target: Others

NB-598 hydrochloride

Cat.No: T12199L

Target: Antifungal

Terbinafine lactate

Cat.No: T6702L

Synonym: DRG-0286,Terbinafine hydrochloride,Lamisil Krem,SF 86-327 hydrochloride,Lamisil,Lamisil AT

Cat.No: T21365

Synonym: KP363,KP 363,Mentax,KP-363,Butop

Cat.No: T11320

Target: Antifungal

Cat. No.	Product Name	Target	Signaling Pathways
T6702	Terbinafine Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Terbinafine (TDT 067) 是念珠菌属的角鲨烯环氧化酶有效的非竞争性抑制剂，Ki 值为 30 nM。它具有抗真菌感染活性。
T1411	Terbinafine hydrochloride KWD 2019,盐酸特比萘芬,Terbinafine HCl,TDT 067 hydrochloride	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Terbinafine hydrochloride (KWD 2019) 具有抗真菌感染活性。它是念珠菌属的角鲨烯环氧化酶的非竞争性抑制剂，Ki 值为 30 nM。它还对某些革兰氏阳性和革兰氏阴性细菌具有抗菌活性。

天然产物

Cat.No: T6702

Synonym: Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067

Target: Antibacterial, Antibiotic, Antifungal

Terbinafine hydrochloride

Cat.No: T1411

Synonym: KWD 2019,盐酸特比萘芬,Terbinafine HCl,TDT 067 hydrochloride

Target: Antibacterial, Antibiotic, Antifungal

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