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Cat. No.	Product Name	Target	Signaling Pathways
T7589	Afamelanotide acetate afamelanotide	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	Afamelanotide acetate 是一种合成的 α-黑素细胞刺激激素类似物和一流的黑皮质素-1 受体激动剂，用于治疗红细胞生成性原卟啉症。
TP1097	Melanotan I 美拉诺坦,美拉诺坦 I,[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I	Others	Others
	Melanotan I 是一种非特异性黑素皮质激素受体 (MCR) 激动剂，是一种 α- 黑素细胞刺激激素 (α-MSH) 类似物，皮下注射可增加黑色素在皮肤中的含量。Melanotan I 可用于辅助美黑。Melanotan I 可用于预防阳光诱发皮肤癌，可用于研究黑色素瘤和男性勃起功能障碍。
T67703	mTOR inhibitor 9b	mTOR	PI3K/Akt/mTOR signaling
	mTOR inhibitor 9b 是一种酶抑制剂，对蛋白激酶mTOR 和磷脂酰肌醇 3-激酶 PIK3CA 具有抑制作用，IC50分别为 0.76nm 和1.262 µM。mTOR inhibitor 9b 具有抗癌活性，可用来研究白血病、皮肤癌、乳腺癌、肺癌和结肠癌。
T11847L	Liarozole R75251 dihydrochloride,利阿唑	P450; Retinoid Receptor	Metabolism
	Liarozole (R75251 dihydrochloride) 是一种咪唑衍生物，是一种具有口服活性的维甲酸 (RA) 代谢阻断剂(RAMBA)，具有抗肿瘤作用。它能够抑制维甲酸依赖的细胞色素P450(CYP26) 4- 羟基化 (IC50=7 μM)，导致组织维甲酸水平增加。
T1120L2	Dacarbazine citrate DTIC citrate
	Dacarbazine citrate is an alkylating agent used to treat cancers of the lymphatic system and malignant melanoma (a type of skin cancer) in patients with certain conditions: islet cell carcinoma (part of the pancreas) Soft tissue sarcoma (cancer of muscles
T32162	Ingenol disoxate LEO-43204,LEO43204,LEO 43204
	Ingenol disoxate, also known as LEO43204, is a Novel 4-Isoxazolecarboxylate Ester of Ingenol with Improved Properties for Treatment of Actinic Keratosis and Other Non-Melanoma Skin Cancers. Ingenol is a natural product found in the sap of the plant Euphor
T11847	Liarozole dihydrochloride R75251 dihydrochloride	Others	Others
	Liarozole dihydrochloride is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).Liarozole dihydrochloride is an imidazole derivative; it is being investigated as a non-hormonal agent in prostate cancer and in the treatment of various other cancers and skin disorders.
T72188	Nicotinamide Hydrochloride Niacinamide Hydrochloride,Nicotinic acid amide Hydrochloride,Niacinamide Hydrochloride ; Nicotinic acid amide Hydrochloride
	Nicotinamide Hydrochloride 是维生素 B3 或烟酸的一种形式，可抑制SIRT2的体外活性，其EC50值为 2 μM。 Nicotinamide Hydrochloride 可抑制 90% 的黑色素瘤细胞数量，并增加细胞内 NAD+、ATP、ROS 水平。Nicotinamide Hydrochloride 抑制黑色素瘤小鼠的肿瘤生长并提高生存率，可用于黑色素瘤等皮肤癌相关的研究。