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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T16269 Nanaomycin A

DNA Methyltransferase; Dehydrogenase; Parasite Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Nanaomycin A 是一种醌类抗生素,可重新激活人类癌细胞中沉默的肿瘤抑制基因。 Nanaomycin A 是 DNMT3B 的特异性抑制剂 (IC50 = 500 nM)。
T77182 Rimteravimab

Rimteravimab (XVR011) 是具强大中和活性、高稳定性及广泛覆盖范围的二价VHH-Fc抗体,并具备沉默Fc效应器功能,可用于对抗SARS-CoV-2 引发的疾病。
T36627 Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)

Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used at a concentration of 10 μM.1It increases the level of H3K4 methylation, including H3K4me1 and H3K4me2 but not H3K9me2 levels, in HCT116 human colon carcinoma cells.2LSD inhibitor (1C) also induces re-expression of the Wnt signaling pathway proteins secreted frizzle-related protei...

化合物

Nanaomycin A
Cat.No: T16269
Synonym:
Target: DNA Methyltransferase, Dehydrogenase, Parasite
Rimteravimab
Cat.No: T77182
Synonym:
Target:
Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)
Cat.No: T36627
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN6198 Mahanine

Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can reverse an epigenetically silenced g

天然产物

Mahanine
Cat.No: TN6198
Synonym:
Target:
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