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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T39172	SMAP-29
	SMAP-29 is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide with strong potential as an antiinfective agent. It effectively permeabilizes bacterial membranes and induces significant alterations in the surface morphology of susceptible microorganisms.
T12934	SMAP-2 DT-1154	Phosphatase	Metabolism
	SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .
T80262	SMAP-18
	SMAP-18是一种具有高生物活性的18氨基酸残基肽酰胺，为SMAP-29 (羊髓系抗菌肽-29) 的缩短版本。SMAP-29对假单胞菌菌株、其他革兰氏阴性菌及多重耐药病原体有很强的抗菌作用。SMAP-18相较于母体SMAP-29，表现出更高的细胞选择性，因其降低了溶血活性同时保留了抗菌能力。
T83738	SMAP 29 (ovine) TFA Sheep Myeloid Antimicrobial Peptide 29
	SMAP 29是一种抗微生物肽，同时也是绵羊防御素前体肽的C末端切割产物。在低盐和高盐条件下，对P. aeruginosa菌株PAO1具有杀菌作用，该作用在能量依赖的发光测定中表现出来（EC50s分别为0.05和0.06 µM）。它还能够以浓度依赖的方式引起绵羊红细胞的溶血。
T2277	Losmapimod GSK-AHAB,GW856553X,6-[5-(环丙基氨基甲酰基)-3-氟-2-甲基苯基]-N-(2,2-二甲基丙基)吡啶-3-甲酰胺,GW856553,洛批莫德,SB856553	p38 MAPK; Autophagy	Autophagy; MAPK
	Losmapimod (GSK-AHAB) 是一种可口服的特异性 p38 MAPK 抑制剂，抑制 p38α 和 p38β 的 pKi 值分别为 8.1 和 7.6。
T28818	SMAPP1
	SMAPP1 is an activator of protein phosphatase 1 (PP1). SMAPP1 induces PP1 activity in vitro and activates latent HIV-1 provirus in cultured and primary T cells.

化合物

Target: Phosphatase

SMAP 29 (ovine) TFA

Cat.No: T83738

Synonym: Sheep Myeloid Antimicrobial Peptide 29

Target:

Losmapimod

Cat.No: T2277

Synonym: GSK-AHAB,GW856553X,6-[5-(环丙基氨基甲酰基)-3-氟-2-甲基苯基]-N-(2,2-二甲基丙基)吡啶-3-甲酰胺,GW856553,洛批莫德,SB856553

Target: p38 MAPK, Autophagy

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01126	MASP2 Protein, Mouse, Recombinant (His) MASP-2,MAP19,MASP1P1,sMap	Mouse	E. coli
	MASP2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.6 kDa and the accession number is Q91WP0.
TMPK-00705	MASP2 Protein, Human, Recombinant (His) MAP19,sMap,MASP-2,MASP1P1	Human	E. coli
	The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population.
TMPK-00581	MASP2 Protein, Rat, Recombinant (E. coli, His) sMap,MASP-2,MASP1P1,MAP19	Rat	E. coli
	MASP2 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
TMPK-00582	MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated MASP1P1,MAP19,sMap,MASP-2	Rat	E. coli
	MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.7 kDa and the accession number is A2VCV7.
TMPK-00496	MASP2 Protein, Cynomolgus, Recombinant (His) MAP19,MASP1P1,MASP-2,sMap	Cynomolgus	E. coli
	MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0.
TMPH-01210	DENR Protein, Human, Recombinant (His & SUMO) DRP,Smooth muscle cell-associated protein 3,DENR,Density-reg...	Human	E. coli
	DENR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.0 kDa and the accession number is O43583.