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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name
L3800 NF-κB 通路分子库

729 compounds
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选;

化合物库

NF-κB 通路分子库
Cat.No: L3800
Compounds: 729
Cat. No. Product Name Target Signaling Pathways
T38460 SN52

SN52 is a powerful, competitive, and cell-permeable inhibitor of NF-κB2. It is a variant of the SN50 peptide. SN52 effectively prevents the nuclear translocation of p52-RelB heterodimers, exhibiting a robust radiosensitization effect on prostate cancer cells. This compound holds significant potential for cancer research purposes.

化合物

SN52
Cat.No: T38460
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T6213 Vinorelbine ditartrate

Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate,长春瑞滨酒石酸盐,酒石酸长春瑞滨

Microtubule Associated; Autophagy Autophagy; Cytoskeletal Signaling
Vinorelbine ditartrate (KW-2307)是一种抗有丝分裂剂,能够抑制 Hela 细胞的增殖,IC50值为 1.25 nM。
T0190 Vinorelbine

长春瑞宾,KW-2307 base

Microtubule Associated Cytoskeletal Signaling
Vinorelbine (KW-2307 base) 是一种半合成的长春花生物碱。它与微管蛋白结合并阻止有丝分裂纺锤体的形成,导致中期肿瘤细胞生长停滞。

天然产物

Vinorelbine ditartrate
Cat.No: T6213
Synonym: Vinorelbine Tartrate,Nor-5'-anhydrovinblastine ditartrate,KW-2307,Navelbine tartrate,长春瑞滨酒石酸盐,酒石酸长春瑞滨
Target: Microtubule Associated, Autophagy
Vinorelbine
Cat.No: T0190
Synonym: 长春瑞宾,KW-2307 base
Target: Microtubule Associated
Cat. No. Product Name Species Expression System
TMPH-00579 Antitoxin RelB Protein, E. coli, Recombinant (His & Myc)

relB,Antitoxin RelB

E. coli E. coli
Antitoxin RelB Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.1 kDa and the accession number is P0C079.
TMPY-01115 DEFB119 Protein, Human, Recombinant (mFc)

DEFB-20,DEFB120,DEFB19,ESC42-RELB,DEFB20,ESC42-RELA...

Human HEK293 Cells
DEFB119 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8N690-1.
TMPH-00783 YafQ Protein, Haemophilus influenzae, Recombinant (His & Myc)

Haemophilus influenzae E. coli
Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB. YafQ Protein, Haemophilus influenzae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 19.4 kDa and the accession number is P44041.
TMPY-02387 NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST)

NFKB3,p65,v-rel avian reticuloendotheliosis viral oncogene h...

Human E. coli
RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth plate chondrocytes where it facilitates chondrogenesis. The v-rel avian reticuloendotheliosis viral oncogene homolog A (RELA) gene encodes the major component of the NF-?B complex. NF-kappaB is a generic name for an evolutionarily conserved transcription-factor system that contributes to the mounting of an eff...

重组蛋白

Antitoxin RelB Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00579
Species: E. coli
Expression System: E. coli
DEFB119 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-01115
Species: Human
Expression System: HEK293 Cells
YafQ Protein, Haemophilus influenzae, Recombinant (His & Myc)
Cat.No: TMPH-00783
Species: Haemophilus influenzae
Expression System: E. coli
NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST)
Cat.No: TMPY-02387
Species: Human
Expression System: E. coli
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