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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T35630	bpV(pic) (potassium hydrate)
	bpV(pic) (potassium hydrate) 可用于生命科学领域的相关研究。其产品编号为 T35630，CAS号为 148556-27-8。
T36081	Trehalose 6-phosphate (potassium salt hydrate)
	Trehalose is a natural non-reducing disaccharide found in plants, invertebrates, fungi, and bacteria.1,2In addition to roles as an energy source and stress protectant, trehalose can function as a signaling molecule.3,4Trehalose 6-phosphate is an intermediate in the biosynthesis of trehalose. It is generated from UDP-glucose and glucose 6-phosphate by trehalose 6-phosphate synthase (TPS or otsA).5In plants, changes in trehalose 6-phosphate levels positively correlate with diurnal changes in sucro...
T29182	YM-358 potassium hydrate YM-358,YM358,YM 358
	YM-358 potassium hydrate is an orally active and long-lasting antagonist of angiotensin type 1 receptor.
T1530	Mitiglinide calcium hydrate KAD-1229 calcium hydrate,米格列奈钙,Mitiglinide calcium,S-21403 calcium hydrate	Potassium Channel	Membrane transporter/Ion channel
	Mitiglinide calcium hydrate (S-21403 calcium hydrate) 是一种 ATP 敏感的 K+通道 (KATPchannel) 拮抗剂，属于促胰岛素化合物。它对 Kir6.2/SUR1 复合物 (胰腺-细胞 KATP 通道) 具有高度特异性，在 2 型糖尿病中有研究价值。
T0038	Doxapram hydrochloride hydrate 多沙普仑盐酸一水合物,盐酸多沙普仑,Doxapram hydrochloride monohydrate,Doxapram HCl	Potassium Channel	Membrane transporter/Ion channel
	Doxapram hydrochloride hydrate (Doxapram HCl) 是 TASK-1，TASK-3和 TASK-1/TASK-3异二聚体通道的抑制剂，EC50分别为410 nM，37 μM 和9 μM。
T67176	Potassium (S)-2-amino-4-carboxybutanoate hydrate
	Potassium (S)-2-amino-4-carboxybutanoate hydrate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67176。
T72272	Glibenclamide potassium Glyburide potassium
	Glibenclamide (Glyburide) potassium 是 Glibenclamide 的钾盐形式。Glibenclamid potassium 以无水和水合物形式存在，与纯 Glibenclamide 相比具有更高的溶解度。

化合物

bpV(pic) (potassium hydrate)

Cat.No: T35630

Synonym:

Target:

Trehalose 6-phosphate (potassium salt hydrate)

Cat.No: T36081

Synonym:

Target:

YM-358 potassium hydrate

Cat.No: T29182

Synonym: YM-358,YM358,YM 358

Target:

Mitiglinide calcium hydrate

Cat.No: T1530

Synonym: KAD-1229 calcium hydrate,米格列奈钙,Mitiglinide calcium,S-21403 calcium hydrate

Target: Potassium Channel

Doxapram hydrochloride hydrate

Cat.No: T0038

Synonym: 多沙普仑盐酸一水合物,盐酸多沙普仑,Doxapram hydrochloride monohydrate,Doxapram HCl

Target: Potassium Channel

Potassium (S)-2-amino-4-carboxybutanoate hydrate

Cat.No: T67176

Synonym:

Target:

Glibenclamide potassium

Cat.No: T72272

Synonym: Glyburide potassium

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T35415	α-D-Glucose-1,6-bisphosphate (potassium salt hydrate)
	α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism. 1.Beitner, R.Regulation of carbohydrate metabol...
T11589	Hydroxycitric acid tripotassium hydrate 柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate	ATP Citrate Lyase; HIF/HIF Prolyl-Hydroxylase; HIF	Angiogenesis; Chromatin/Epigenetic; Metabolism
	Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) 是一种藤黄果的主要活性成分，也是一种柠檬酸的衍生物。它可竞争性抑制柠檬酸裂解酶 (ATP citrate lyase) ，并具有减肥作用。它有效抑制结石形成，并抑制HIF，具有抗氧化，抗炎和抗肿瘤活性。
T37709	2,2,2-Trichloroethanol	Potassium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	2,2,2-Trichloroethanol 是非经典的 K2P 通道 TREK-1和 TRAAK 的激动剂。
T75333	Quinine hemisulfate hydrate
	Quinine hemisulfate hydrate，一种从金鸡纳树皮提取的生物碱，具有抗疟疾效果。作为钾离子通道 (potassium channel) 抑制剂，它能够抑制由电压脉冲触发的MT mSlo3 (KCa5.1) 通道在+100 mV下的电流活动，其IC50值达169 μM。