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Cat. No. Product Name Target Signaling Pathways
T2710 TCS 1102

OX Receptor GPCR/G Protein; Neuroscience
TCS 1102 是双食欲素受体拮抗剂,对 OX1和OX2受体的Ki 分别为3和 0.2 nM。
T2371 Emapunil

AC-5216,XBD-173

Others Others
Emapunil (XBD-173) 是一种选择性的、口服有效的TSPO(一种线粒体苯二氮受体) 的配体。在多种动物模型中,它显示出抗焦虑和抗抑郁特性。
T13329 Vofopitant

GR 205171

Neurokinin receptor GPCR/G Protein; Neuroscience
Vofopitant (GR 205171) 是一种有效的 NK1 receptor 拮抗剂,具有抗焦虑和止吐活性,可用于研究创伤后应激障碍(PTSD)。
T40775 SSR411298

SSR411298

SSR411298 is a reversible, orally active compound that selectively inhibits fatty acid amide hydrolase (FAAH). Its potential lies in the field of post-traumatic stress disorder (PTSD) research.
T68579 Fluvoxamine acid

Fluvoxamine acid is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the treatment of obsessive-compulsive disorder (OCD), and is also used to treat major depressive disorder (MDD), and anxiety disorders such as panic disorder and post-traumatic stress disorder (PTSD).
T61578 BRD3731

BRD3731 is a selective inhibitor of GSK3β, demonstrating an IC50 value of 15 nM for GSK3β and 215 nM for GSK3α. Due to its inhibitory properties, BRD3731 holds promise for investigating various medical conditions, including post-traumatic stress disorder (PTSD), psychiatric disorders, diabetes, and neurodegenerative disorders [1].
T79056 Orexin receptor modulator-1

Orexin receptormodulator-1 是一款针对食欲素受体的调节剂,主要应用于物质成瘾、惊恐障碍、焦虑、创伤后应激障碍 (PTSD)、疼痛、抑郁、季节性情感障碍、进食障碍及高血压的科研领域。
T79806 5-HT2A&5-HT2C agonist-1

5-HT Receptor GPCR/G Protein; Neuroscience
5-HT2A&5-HT2C agonist-1 (Example 2) 是一种选择性的5-HT2A和5-HT2C受体激动剂,其IC50值分别为196 nM和0.9 nM。本化合物主要应用于研究抑郁症、酒精依赖、烟草和可卡因成瘾、炎症、丛集性头痛、PTSD、癫痫等中枢神经系统相关疾病。

化合物

TCS 1102
Cat.No: T2710
Synonym:
Target: OX Receptor
Emapunil
Cat.No: T2371
Synonym: AC-5216,XBD-173
Target: Others
Vofopitant
Cat.No: T13329
Synonym: GR 205171
Target: Neurokinin receptor
SSR411298
Cat.No: T40775
Synonym: SSR411298
Target:
Fluvoxamine acid
Cat.No: T68579
Synonym:
Target:
BRD3731
Cat.No: T61578
Synonym:
Target:
Orexin receptor modulator-1
Cat.No: T79056
Synonym:
Target:
5-HT2A&5-HT2C agonist-1
Cat.No: T79806
Synonym:
Target: 5-HT Receptor
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