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Search Results for " phosphatidic acid "

9

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T21729 (±)-Lisofylline

Others Others
(±)-Lisofylline 是一种对映异构体特异性、烷基取代的甲基黄嘌呤,在下调白细胞活化方面具有特异性和有效的活性。它是一种抗炎剂。
T67073 1,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt)

1,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67073。
T72322 R 59-022 hydrochloride

DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride

5-HT Receptor; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; Neuroscience
R 59-022 hydrochloride (DKGI-I hydrochloride) 是一种 5-HT Receptor 拮抗剂,可激活蛋白激酶 C (PKC)。R 59-022 hydrochloride 是一种 DGK 抑制剂 (IC50:2.8 µM),可抑制 OAG 磷酸化为 OAPA。R 59-022 增强血小板中凝血酶诱导的甘油二酯的产生,并抑制嗜中性粒细胞中磷脂酸的产生。
T37691 Phosphatidic Acids (egg) (ammonium salt)

Phosphatidic acid is a phospholipid and an intermediate in glycerolipid biosynthesis. It is a transient intermediate in the synthesis of various phospholipid species that is synthesized de novo in cells via multiple routes, including the glycerol-3 phosphate and dihydroxyacetone phosphate pathways, enzymatic conversion of phosphatidylcholine by phospholipase D, and acetylation of lysophosphatidic acid by lysoPA-acyltransferase, among others. It has roles in shaping cellular membranes, cellular ...
T16709 R 59-022

Diacylglycerol kinase inhibitor I,DKGI-I

Others Others
R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neu
T10005 1,2-Dipalmitoyl-sn-glycerol 3-phosphate

Others Others
1,2-Dipalmitoyl-sn-glycerol 3-phosphate, a phosphatidic acid, is a human endogenous metabolite.
T37122 1,2-Dilinoleoyl-sn-glycerol

1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.
T36907 1-Oleoyl Lysophosphatidic Acid

Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid

1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed by phosphorylation of DAG by diglycerol kinase.[1] Hydrolysis of the fatty acid at the sn-2 position by phospholipase A2 (PLA2) yields bioactive LPA. LPA binds to one of five differe...
T76120 Phospholipase D

PhospholipaseD (PLD) ,即磷脂酶 D,是磷脂酶超家族的一种酶,广泛存在于细菌、酵母、植物、动物和病毒中,常用于生化研究。PhospholipaseD 可以催化甘油磷脂的磷酸二酯键水解,产生磷脂酸和可溶性胆碱。PhospholipaseD 参与了多种疾病相关过程,包括糖尿病、动脉粥样硬化形成、肥胖、肿瘤发生、免疫反应和神经内分泌功能。

化合物

(±)-Lisofylline
Cat.No: T21729
Synonym:
Target: Others
1,2-Distearoyl-sn-glycero-3-phosphatidic acid (Na+ salt)
Cat.No: T67073
Synonym:
Target:
R 59-022 hydrochloride
Cat.No: T72322
Synonym: DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride
Target: 5-HT Receptor, PKC
Phosphatidic Acids (egg) (ammonium salt)
Cat.No: T37691
Synonym:
Target:
R 59-022
Cat.No: T16709
Synonym: Diacylglycerol kinase inhibitor I,DKGI-I
Target: Others
1,2-Dipalmitoyl-sn-glycerol 3-phosphate
Cat.No: T10005
Synonym:
Target: Others
1,2-Dilinoleoyl-sn-glycerol
Cat.No: T37122
Synonym:
Target:
1-Oleoyl Lysophosphatidic Acid
Cat.No: T36907
Synonym: Oleoyl-sn-3-Glycerophosphate,1-Oleoyl LPA,1-Oleoyl Lysophosphatidic Acid
Target:
Phospholipase D
Cat.No: T76120
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T10005L 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium

Endogenous Metabolite Metabolism
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 是一种人内源性代谢物,是一种磷酸酯。
T69446 Cochlioquinone A

Cochlioquinone A is an inhibitor of diacylglycerol kinase (DGK) and diacylglycerol acyltransferase (DGAT). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma and has also been shown to compete with macrophage inflammatory protein-1α for binding to human CCR5 chemokine receptors.

天然产物

1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
Cat.No: T10005L
Synonym:
Target: Endogenous Metabolite
Cochlioquinone A
Cat.No: T69446
Synonym:
Target:
TargetMol Loading
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