Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7587 |
Tenapanor
RDX-5791,RDX 5791,AZD 1722,Tenapanor free base,RDX5791,AZD-1722,AZD1722 |
Sodium Channel | Membrane transporter/Ion channel |
Tenapanor (RDX 5791) 是钠氢离子交换NHE3的有效抑制剂, 对人和大鼠NHE3的IC50分别是5和10 nM。 | |||
T6344 |
Sevelamer hydrochloride
Sevelamer HCl |
FXR; Autophagy | Autophagy; Metabolism |
Sevelamer hydrochloride (Sevelamer HCl) 是一种磷酸盐结合药物,用于通过与膳食磷酸盐结合并阻止其吸收来治疗高磷血症。 | |||
T21417 |
Dihydrotachysterol
Hytakerol,HSDB-3314,双氢速甾醇,HSDB3314,Parterol,HSDB 3314 |
||
Dihydrotachysterol (DHT) is a biologically active synthetic analog of vitamin D. It promotes intestinal absorption of active calcium and phosphate . It is also beneficial in the treatment of hypoparathyroidism. | |||
T70605 | NaPi2b Inhibitor 15 | ||
NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. The inhibition of NaPi2b, responsible for intestinal phosphate absorption, is considered to reduce serum phosphate levels, making it a promising therapeutic approach for hyperphosphatemia | |||
T76151 | Glycerol kinase | ||
Glycerol kinase (GyK) 甘油激酶是一种细菌糖激酶,常用于生化研究。Glycerol kinase 通过将三醇转化为甘油-3-p (G3P) 来催化甘油代谢。Glycerol kinase 对于调节细胞中不依赖通道/促进因子的甘油摄取至关重要。 |