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8

抑制剂 & 化合物

4

天然产物

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Cat. No. Product Name Target Signaling Pathways
T8926 Salcaprozate sodium

8-(2-羟基苯甲酰胺基)辛酸钠,SNAC

Others Others
Salcaprozate sodium (SNAC) 是口服吸收促进剂,有作为口服形式的肝素和胰岛素递送剂的潜力。它可提高非共价大分子络合引起的亲脂性,从而增加小肠上皮细胞的被动跨细胞渗透。
T17067 TH-237A

meso-GS 164

Others Others
TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.
T20251 Butyl carbitol acetate

NSC 5175,NSC5175,NSC-5175

Butyl carbitol acetate enables deep permeation into the textile, with its low vapor pressure and boiling point.
T41038 Sephadex G 50

Sephadex G 50 is a gel filtration medium commonly utilized in gel permeation chromatography for effective fractionation of glycopeptide mixtures.
T82176 HR1

HR1是一种乳突蛋白酶,可增加人红细胞膜渗透性,并能诱导细菌细胞质膜和肥大细胞质膜透化。
T81079 Substance P (2-11)

Substance P (2-11)为P物质(SP)片段肽,具有对豚鼠回肠产生收缩活性的特性。同时,Substance P (2-11)能够抑制3H SP在BBMEC单分子层中的渗透。
T60691 AChE/BChE/BACE-1-IN-2

AChE/BChE/BACE-1-IN-2 (Compound 4o) 表现出显著的抗氧化潜力和对PAS-AChE 的强大的结合能力。AChE/BChE/BACE-1-IN-2 是口服有效的AChE、BACE-1和BChE 抑制剂,对 hAChE、hBACE-1 和hBChE 的IC50分别为 0.069、0.097 和0.127 μM。AChE/BChE/BACE-1-IN-2 显示出对潜在的 Aβ 聚集物的分解能力和针对 Aβ 诱导的应激的神经保护作用。
T36929 Pal-KTTKS (acetate)

Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when used at concentrations of 0.002, 0.004, and 0.008 wt%.2 Following topical administration, pal-KTTKS (50 μg/cm2) is found in the stratum corneum, epidermis, and dermis of isolated hairless mouse skin.1 It can self-assemble into flat tapes and extended fibrillar structures.3 Pal-KTTKS...

化合物

Salcaprozate sodium
Cat.No: T8926
Synonym: 8-(2-羟基苯甲酰胺基)辛酸钠,SNAC
Target: Others
TH-237A
Cat.No: T17067
Synonym: meso-GS 164
Target: Others
Butyl carbitol acetate
Cat.No: T20251
Synonym: NSC 5175,NSC5175,NSC-5175
Target:
Sephadex G 50
Cat.No: T41038
Synonym:
Target:
HR1
Cat.No: T82176
Synonym:
Target:
Substance P (2-11)
Cat.No: T81079
Synonym:
Target:
AChE/BChE/BACE-1-IN-2
Cat.No: T60691
Synonym:
Target:
Pal-KTTKS (acetate)
Cat.No: T36929
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T8047 Menthyl acetate

乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-​Menthyl acetate,L-​Menthyl acetate

Others Others
​Menthyl acetate (L-​Menthyl acetate) 是一种可有效增强 5-氨基乙酰丙酸 (ALA) 皮肤渗透的 L-薄荷醇衍生物。​
TN5118 Taxol C

P-gp Membrane transporter/Ion channel; Neuroscience
Taxol C 可以减少与 P-糖蛋白转运蛋白的相互作用,从而增加紫杉烷类向大脑的渗透。
TN1081 Hirsuteine

Dopamine Receptor GPCR/G Protein; Neuroscience
Hirsuteine 是提取自钩藤属植物中的吲哚生物碱。它可阻断离子渗透通过烟碱受体通道复合物,非竞争性地拮抗烟碱介导的多巴胺释放。
T40910 Cognac oil

Cognac oil, predominantly derived from wine lees, exhibits distinctive fatty acid compositions, characterized by high proportions of Palmitic acid (59.26%), Linoleic acid (11.92%), Myristic acid (8.97%), and Oleic acid (8.3%) among other fatty acids. Notably, the application of Cognac oil enhances the permeability of Rhodamine 6G (R6G) across various membranes, resulting in a generalized increase in permeation.

天然产物

Menthyl acetate
Cat.No: T8047
Synonym: 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-​Menthyl acetate,L-​Menthyl acetate
Target: Others
Taxol C
Cat.No: TN5118
Synonym:
Target: P-gp
Hirsuteine
Cat.No: TN1081
Synonym:
Target: Dopamine Receptor
Cognac oil
Cat.No: T40910
Synonym:
Target:
TargetMol Loading
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