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10

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T19780 2,2′-Dipyridyl disulfide

2,2'-Dipyridyl disulfide,OPSS,2,2'-二硫二吡啶,Aldrithiol 2,Orthopyridyl disulfide

Others Others
2,2′-Dipyridyl disulfide (Aldrithiol 2) 是肽化学中的常用试剂,是测定巯基的有用试剂,常用于氧化还原缩合以形成肽键或用于偶联反应以形成二硫键连接的异二聚体。
T6851 NADP sodium salt

Sodium NADP,三磷酸吡定核苷酸,辅酶Ⅱ(NADP 钠盐)

Others Others
NADP sodium salt (Sodium NADP) 是一种烟酰胺腺嘌呤二核苷酸,是一种氧化还原辅助因子。它是代谢中电子转移的关键辅因子,能够被交替氧化 (NADP+) 和还原 (NADPH)。
T1415 Gemfibrozil

吉非罗齐,CI-719,Jezil,Decrelip,Lopid

P450; Adrenergic Receptor; PPAR DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Gemfibrozil (CI-719) 是一种PPAR-α激活剂,可作为降脂药。它也是P450非选择性抑制剂,对 CYP2C9、2C19、2C8 和 1A2 的Ki 值分别为 5.8、24、69 和 82 μM。
T7650L Resazurin

Resazoin,Diazoresorcinol,Azoresorcin,Resazurine

Resazurin is used as an oxidation-reduction indicator in cell viability.
T76118 Malate dehydrogenase

Malate dehydrogenase 催化草酰乙酸盐和苹果酸盐的相互转化,与二核苷酸辅酶的氧化/还原相关。
T64537 Guanosine 5′-diphospho-β-L-fucose sodium salt

GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in most organisms.
T37789 Riboflavin 5'-monophosphate (sodium salt hydrate)

Riboflavin 5'-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalyzing oxidation and reduction reactions in a variety of biosynthetic pathways. FMN also binds the FMN riboswitch (RFN element) on RNA to alter gene regulation. FMN is a substrate of FMN phosphohydrolases and is used to study their function.
T37932 15-keto Latanoprost

Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis produces 15-keto latanoprost. 15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-k...
T37934 15-keto-17-phenyl trinor Prostaglandin F2α

15-keto-17-phenyl trinor Prostaglandin F2α

Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compo...
T65396 Piperazine 2HCl

Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspected toxicoses in cats. Piperazine neurotoxicity in cats and dogs usually was manifested by muscle tremors, ataxia, and/or behavioral disturbances within 24 hours after estimated daily dose(s) between 20 and 110 mg/kg[1]. For di-substituted derivatives, ciprofloxacin was selected an...

化合物

2,2′-Dipyridyl disulfide
Cat.No: T19780
Synonym: 2,2'-Dipyridyl disulfide,OPSS,2,2'-二硫二吡啶,Aldrithiol 2,Orthopyridyl disulfide
Target: Others
NADP sodium salt
Cat.No: T6851
Synonym: Sodium NADP,三磷酸吡定核苷酸,辅酶Ⅱ(NADP 钠盐)
Target: Others
Gemfibrozil
Cat.No: T1415
Synonym: 吉非罗齐,CI-719,Jezil,Decrelip,Lopid
Target: P450, Adrenergic Receptor, PPAR
Resazurin
Cat.No: T7650L
Synonym: Resazoin,Diazoresorcinol,Azoresorcin,Resazurine
Target:
Malate dehydrogenase
Cat.No: T76118
Synonym:
Target:
Guanosine 5′-diphospho-β-L-fucose sodium salt
Cat.No: T64537
Synonym:
Target:
Riboflavin 5'-monophosphate (sodium salt hydrate)
Cat.No: T37789
Synonym:
Target:
15-keto Latanoprost
Cat.No: T37932
Synonym:
Target:
15-keto-17-phenyl trinor Prostaglandin F2α
Cat.No: T37934
Synonym: 15-keto-17-phenyl trinor Prostaglandin F2α
Target:
Piperazine 2HCl
Cat.No: T65396
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T5067 Flavin adenine dinucleotide disodium salt

Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2

Others; Endogenous Metabolite Metabolism; Others
Flavin adenine dinucleotide disodium salt (FAD sodium salt) 是一种辅酶,作用是促进细胞氧化还原反应中黄素酶的电子转移。
T4838 (S)-Malic acid

L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸

Others; Endogenous Metabolite Metabolism; Others
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) 是天然存在的二羧酸,是水果酸甜味的来源,常用作食品添加剂。

天然产物

Flavin adenine dinucleotide disodium salt
Cat.No: T5067
Synonym: Flavin Adenine Dinucleotide Disodium,黄素腺嘌呤二核苷酸二钠,FAD sodium salt,FAD-Na2
Target: Others, Endogenous Metabolite
(S)-Malic acid
Cat.No: T4838
Synonym: L-(-)-Malic acid,(S)-(-)-HYDROXYSUCCINIC ACID,(S)-2-Hydroxysuccinic acid,L-苹果酸
Target: Others, Endogenous Metabolite
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