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21

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T8395 Nomegestrol acetate

Others; Progesterone Receptor Others
Nomegestrol acetate 是一种孕酮受体的完全激动剂,是一种高选择性孕激素。
TP1929L1 Saralasin acetate(34273-10-4 free base)

RAAS Endocrinology/Hormones
Saralasin acetate(34273-10-4 free base) 是一种非选择性血管紧张素 II 拮抗剂。
T0171 Norethynodrel

Lynestrol,异炔诺酮

Estrogen/progestogen Receptor Endocrinology/Hormones
Norethynodrel (Lynestrol) 是一种合成的孕激素,其作用和用途类似于孕酮。它已被用于治疗功能性子宫出血和子宫内膜异位症。它作为避孕药,通常与 MESTRANOL 联合使用。
T1514 Norethindrone

Norethisterone,炔诺酮

Estrogen/progestogen Receptor; Progesterone Receptor Endocrinology/Hormones; Others
Norethindrone (Norethisterone) 是孕激素,能够用于子宫内膜异位症、由激素水平异常引起的子宫出血和继发性闭经的研究。
T6858 Hydroxyprogesterone caproate

Primolut Depot,Delalutin,Hormofort,己酸孕酮,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate

Autophagy Autophagy
Hydroxyprogesterone caproate (Delalutin) 是一种甾体,是一种人工合成的孕激素。
T50086 Clomesone

Others Others
Clomesone 是一种合成的非甾体药物,可用作分子结构单元。它是一种常用于治疗女性不孕的药物,通过阻断大脑中雌激素的作用发挥作用,已被证明对患有多囊卵巢综合征和其他不孕问题的女性有效诱导排卵。
T2527 Ulipristal acetate

Ulipristal,醋酸乌利司他,CDB-2914

Estrogen/progestogen Receptor; Progesterone Receptor; Autophagy Autophagy; Endocrinology/Hormones; Others
Ulipristal acetate (CDB-2914) 是一种具有抗孕酮活性的选择性孕酮受体调节剂。它可抑制子宫平滑肌瘤病的生长。它通过抑制或延迟排卵和影响子宫内膜组织,可用作紧急避孕药。
T34234 R 151885

R-151885,R151885

R 151885 delays ovulation in rats.
T68775 Etamestrol

Etamestrol is a synthetic, steroidal estrogen described as an ovulation inhibitor or hormonal contraceptive
T34302 Retroprogesterone

Retroprogesterone, a progestin, may be used for menstrual irregularities in adolescence, for the maintenance of threatened pregnancy, and possibly as an ovulation stimulant.
T19697 Norgestomet

SC21009,Norprogesterone, Syncro-Mate B,SC-21009,SC 21009

Norgestomet is a steroidal progestin of the 19-norprogesterone group used in veterinary medicine to control estrus and ovulation in cattle. In addition to the progesterone receptor, norgestomet possesses a weak (micromolar) affinity for the glucocorticoid
T76312L sGnRH-A acetate

sGnRH-A醋酸盐是一种鲑鱼促性腺激素释放激素(GnRH)类似物。它能促进生长激素的分泌,并用作人工授精时的排卵诱导剂。
T76593 (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)

'(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)' 为一种GnRH类似物,主要用于诱导养殖鱼类排卵和/或产卵。
T62571 Clomifene hydrochloride

Clomifene hydrochloride 可以诱导排卵,能够用于不孕症。hydrochloride 是一种简单的、相对安全的、易于给药且耐受性良好的、口服具有活力的化合物。
T83498 [D-Phe2,D-Ala6]-LH-RH

Wy 18185

[D-Phe2,D-Ala6]-LH-RH 为有效LH-RH拮抗剂,展现了显著的抗LH/FSH-RH及抗排卵活性。
T36916 Estrone-3-Glucuronide (sodium salt hydrate)

Estrone-3-Glucuronide is a metabolite of the primary premenopausal estrogen 17β-estradiol .1,2Urinary levels of estrone-3-Glucuronide peak approximately 36 hours prior to ovulation and have been used as a marker of fertility in women. 1.Blackwell, L.F., Brown, J.B., and Cooke, D.Definition of the potentially fertile period from urinary steroid excretion rates. Part II. A threshold value for pregnanediol glucuronide as a marker for the end of the potentially fertile period in the human menstrual ...
T76352 Lamprey LH-RH I

Lamprey LH-RH I 是一种促性腺激素释放激素,作用于提高血浆类固醇水平并刺激七鳃鳗排卵,而对其他动物模型无影响。
T76312 sGnRH-A

sGnRH-A,一种鲑鱼促性腺激素释放激素(GnRH)类似物,能够促进生长激素的分泌,并作为人工授精中的排卵诱导剂使用。
T76566 Fsh receptor-binding inhibitor fragment(bi-10)

FSHreceptor-binding inhibitor fragment(bi-10) 是一种有效的 FSH 拮抗剂。FSHreceptor-binding inhibitor fragment(bi-10) 阻断 FSH 与 FSHR 的结合,并在受体水平上改变 FSH 的作用。FSHreceptor-binding inhibitor fragment(bi-10) 导致小鼠排卵抑制和卵泡闭锁。FSHreceptor-binding inhibitor fragment(bi-10) 通过下调卵巢中 FSHR 和 ERβ的过度表达来抑制卵巢癌发生。
T70266 Acyline

Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. Acyline inhibits basal and GnRH-stimulated serum testosterone concentrations in male dogs. Acyline prevented ovulation, but did not affect ovarian follicular development or gestational corpora lutea in the domestic cat. A single dose of the potent gonadotropin-releasing hormone antagonist acyline suppresses gonadotropins and testosterone for 2 weeks in hea...
T70309 Dicetrorelix pamoate

Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently lutein...

化合物

Nomegestrol acetate
Cat.No: T8395
Synonym:
Target: Others, Progesterone Receptor
Saralasin acetate(34273-10-4 free base)
Cat.No: TP1929L1
Synonym:
Target: RAAS
Norethynodrel
Cat.No: T0171
Synonym: Lynestrol,异炔诺酮
Target: Estrogen/progestogen Receptor
Norethindrone
Cat.No: T1514
Synonym: Norethisterone,炔诺酮
Target: Estrogen/progestogen Receptor, Progesterone Receptor
Hydroxyprogesterone caproate
Cat.No: T6858
Synonym: Primolut Depot,Delalutin,Hormofort,己酸孕酮,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate
Target: Autophagy
Clomesone
Cat.No: T50086
Synonym:
Target: Others
Ulipristal acetate
Cat.No: T2527
Synonym: Ulipristal,醋酸乌利司他,CDB-2914
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Autophagy
R 151885
Cat.No: T34234
Synonym: R-151885,R151885
Target:
Etamestrol
Cat.No: T68775
Synonym:
Target:
Retroprogesterone
Cat.No: T34302
Synonym:
Target:
Norgestomet
Cat.No: T19697
Synonym: SC21009,Norprogesterone, Syncro-Mate B,SC-21009,SC 21009
Target:
sGnRH-A acetate
Cat.No: T76312L
Synonym:
Target:
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
Cat.No: T76593
Synonym:
Target:
Clomifene hydrochloride
Cat.No: T62571
Synonym:
Target:
[D-Phe2,D-Ala6]-LH-RH
Cat.No: T83498
Synonym: Wy 18185
Target:
Estrone-3-Glucuronide (sodium salt hydrate)
Cat.No: T36916
Synonym:
Target:
Lamprey LH-RH I
Cat.No: T76352
Synonym:
Target:
sGnRH-A
Cat.No: T76312
Synonym:
Target:
Fsh receptor-binding inhibitor fragment(bi-10)
Cat.No: T76566
Synonym:
Target:
Acyline
Cat.No: T70266
Synonym:
Target:
Dicetrorelix pamoate
Cat.No: T70309
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2S2108 Coixol

薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA

Others; Antibacterial Microbiology/Virology; Others
Coixol (MBOA) 是一种从薏苡仁中提取的多酚,有抗菌和抗肿瘤作用。
T1688 Pregnanediol

5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇

Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) 是一种黄体酮的主要代谢物 (metabolite),能够通过尿液排出。它提供了一种间接测定体内孕激素水平的方法。

天然产物

Coixol
Cat.No: T2S2108
Synonym: 薏苡素,6-methoxybenzoxazolone,6-MBOA,6-Methoxy-2-benzoxazolinone,MBOA
Target: Others, Antibacterial
Pregnanediol
Cat.No: T1688
Synonym: 5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇
Target: Estrogen/progestogen Receptor, Endogenous Metabolite
TargetMol Loading
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