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Cat. No.	Product Name	Target	Signaling Pathways
T15812	LY2979165 mGlu2 agonist	GluR	Neuroscience
	LY2979165 (mGlu2 agonist) 是 mGluR2 的正构激动剂，可用于作为抗抑郁药的研究。
T61972	Pomaglumetad methionil hydrochloride LY2140023 hydrochloride	GluR	Neuroscience
	Pomaglumetad methionil hydrochloride (LY2140023 hydrochloride) (LY2140023 hydrochloride) 是的 LY404039 的蛋氨酸前药，具有口服活性。LY404039是一种选择性 mGlu2/3 受体激动剂。Pomaglumetad methionil hydrochloride 可用于精神分裂症的研究。
T6022	LY404039 pomaglumetad	Glucocorticoid Receptor; GluR	Endocrinology/Hormones; Neuroscience
	LY404039 (pomaglumetad) 是可口服的mGluR2和mGluR3选择性激动剂，有抗精神病和抗焦虑的作用。它对重组人mGluR2和mGluR3的Ki 分别为 149 和 92 nM，比对其他受体/转运蛋白的抑制性高 100 倍以上。
T28928	TASP0433864
	TASP0433864 is a positive allosteric modulator of metabotropic glutamate 2 receptor with EC50 values of 199 and 206 nM at human and rat mGlu2 receptors, respectively, without exerting agonist activity at rat mGlu2 receptor.
T15809	LY2812223	LIM Kinase	Cell Cycle/Checkpoint
	LY2812223 is a highly effective and functionally selective mGlu2 receptor agonist. It has a mGlu2 binding affinity for mGlu2 and mGlu3 (Ki=144 nM and 156 nM, respectively).
T15817	Eglumegad Eglumetad,LY354740	Others	Others
	Eglumegad is a highly effective and selective agonist of group II (mGlu2/3) receptor (IC50s: 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively).
T12520	Pomaglumetad methionil LY2140023 hydrate	GluR	Neuroscience
	Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.
T27950	LY389795 LY-389795,LY 389795
	LY389795 is an agonist of group II (mGlu2/3) metabotropic glutamate receptor, it is used in inflammatory pain models.
T70619	LY2934747
	LY2934747 is a novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo.
T11906	LY 541850	GluR	Neuroscience
	LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human ionotropic and metabotropic glutamate (mGlu) receptors expressed in non-neuronal cells.
T78094	Eglumegad hydrochloride LY354740 hydrochloride,Eglumetad hydrochloride
	Eglumegad (LY354740) hydrochloride是一种高效且选择性的group II (mGlu2/3) receptor激动剂，其对人mGlu2和mGlu3受体的IC50值分别是5和24 nM。该化合物能够保护神经元不受NMDA毒性影响，并表现出抗焦虑及抗精神病样作用。