3577
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40030 |
Thalidomide 4'-ether-alkylC2-amine hydrochloride
halidomide-linker 6 |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) 包含基于 Thalidomide 的 cereblon 配体和 linker,是合成的 E3 连接酶配体-linker 偶联物,可应用于 PROTAC 技术。 | |||
T18639 |
Cl-C6-PEG4-O-CH2COOH
PROTAC Linker 4 |
Others | Others |
Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) 是一种有效的基于聚乙二醇的 PROTAC 连接剂,常被用于 PROTAC 合成氯烷(HaloPROTACs)。 | |||
T17233 |
Vipivotide tetraxetan Linker
PSMA-617 Linker |
Others | Others |
Vipivotide tetraxetan Linker (PSMA-617 Linker) is a noncleavable peptide linker utilized in the synthesis of Vipivotide tetraxetan (PSMA-617), a ligand instrumental in producing 177Lu-PSMA-617. This radioactive molecule is applied in the treatment of prostate cancer[1]. | |||
T39629 |
BRD4 ligand-Linker Conjugate 1
BRD4 ligand-Linker Conjugate 1 |
||
BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules utilized for targeted protein degradation. | |||
T39609 |
cIAP1 Ligand-Linker Conjugates 16
cIAP1 Ligand-Linker Conjugates 16 |
||
cIAP1 Ligand-Linker Conjugates 16 refers to a specific type of ligase ligand-linker conjugate, possessing the ability to engage with E3 ligases, which finds application in the synthesis of PROTACs. | |||
T2056 |
VEGFR-2-IN-5
2, 4-Pyrimidinediamine with linker,UNC0064-12,2,4-Pyrimidinediamine with linker |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
VEGFR-2-IN-5 (UNC0064-12) 是 VEGFR2 抑制剂。 | |||
T7759 |
Thalidomide-O-amido-C4-NH2 TFA
E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T15189 |
Thalidomide-O-amido-C4-N3
E3 ligase Ligand-Linker Conjugates 18,Cereblon Ligand-Linker Conjugates 4 |
Others; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) 是一种 E3 连接酶配体- linker 偶联物,包含基于 Thalidomide 的 cereblon 配体和 linker。 | |||
T17922 |
(S,R,S)-AHPC-PEG3-NH2 hydrochloride
VHL Ligand-Linker Conjugates 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 5,VH032-PEG3-NH2 hydrochloride,VHL Ligand-Linker Conjugates 1 HCl |
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) 是一种 E3 ligase ligand-linker conjugate,包含了 (S,R,S)-AHPC-based VHL ligand 和 3-unit PEG linker。 | |||
T17916 |
Pomalidomide-PEG4-C2-NH2
Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22 |
Others; Ligand for E3 Ligase | Others; PROTAC |
Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) 是一种合成的 E3 连接酶配体- linker 偶联物,用于 PROTAC 技术中。 | |||
T17919 |
Thalidomide-O-amido-C6-NH2 TFA
E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate,Cereblon Ligand-Linker Conjugates 11 TFA,E3 Ligase Ligand-Linker Conjugates 25 TFA |
Others; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物。可用于 PROTAC 的合成分子。 | |||
T17325 |
Pomalidomide-PEG4-C-COOH
Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1 |
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) 包含基于 Pomalidomide 的 cereblon 配体和 4 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T7760 |
Thalidomide-O-amido-C3-NH2 TFA
Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA |
E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | PROTAC |
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物,。 | |||
T17893 |
cIAP1 Ligand-Linker Conjugates 5
E3 ligase Ligand-Linker Conjugates 39 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 5 is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 5, is specifically designed for the development of SNIPERs[1]. | |||
T17908 |
VHL Ligand-Linker Conjugates 15
E3 Ligase Ligand-Linker Conjugates 56 |
Others | Others |
VHL Ligand-Linker Conjugates 15 is a chemical compound that combines a VHL ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is specifically designed for the creation of PROTACs[1]. | |||
T17921 |
(S,R,S)-AHPC-PEG4-N3
VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4 |
Others; PROTAC Linker | Others; PROTAC |
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both commonly employed in PROTAC technology. | |||
T17920 |
(S,R,S)-AHPC-PEG1-N3
VHL Ligand-Linker Conjugates 9,VH032-PEG1-N3,E3 ligase Ligand-Linker Conjugates 3 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG1-N3 (E3 ligase Ligand-Linker Conjugates 3) 是 E3 连接酶配体和linker 连接得到的 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 1 个单元 PEG linker。 | |||
T17730 | CL2 Linker | Others | Others |
CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2]. | |||
T7758 |
Thalidomide-O-amido-PEG3-C2-NH2 TFA
E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA) |
Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) 包含基于 Thalidomide 的 cereblon 配体和 3 个单元的 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T17918 |
Thalidomide-O-amido-PEG2-C2-NH2 TFA
E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA |
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) 包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T17889 |
cIAP1 Ligand-Linker Conjugates 14
E3 ligase Ligand-Linker Conjugates 36 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 14 consist of an IAP ligand that targets the E3 ubiquitin ligase and a PROTAC linker. These conjugates, known as cIAP1 Ligand-Linker Conjugates 14, are used in the development of SNIPERs[1]. | |||
T17896 |
cIAP1 Ligand-Linker Conjugates 4
E3 ligase Ligand-Linker Conjugates 42 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 4 is a chemical compound that comprises an IAP ligand specifically designed for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 4, has the potential to be utilized in the development of SNIPERs[1]. | |||
T17885 |
cIAP1 Ligand-Linker Conjugates 11
E3 ligase Ligand-Linker Conjugates 33 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in the development of SNIPERs[1], allowing for the targeted degradation of proteins. | |||
T17891 |
cIAP1 Ligand-Linker Conjugates 2
E3 ligase Ligand-Linker Conjugates 37 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 2 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. This compound is particularly useful in the design of SNIPERs [1]. | |||
T17899 |
cIAP1 Ligand-Linker Conjugates 9
E3 ligase Ligand-Linker Conjugates 45 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 9 feature an IAP ligand specifically targeting the E3 ubiquitin ligase, along with a PROTAC linker. It is valuable tools for developing SNIPERs[1]. | |||
T15190L |
(S,R,S)-AHPC-PEG4-NH2
VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) 是一种合成的 E3 连接酶配体-接头偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 4 单元 PEG 接头。 | |||
T17909 |
(S,R,S)-AHPC-PEG3-N3
VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12 |
Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 3 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T17901 |
cIAP1 Ligand-Linker Conjugates 10
E3 ligase Ligand-Linker Conjugates 47 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROTAC linker. SNIPERs can be developed using cIAP1 Ligand-Linker Conjugates 10. | |||
T17892 |
cIAP1 Ligand-Linker Conjugates 12
E3 ligase Ligand-Linker Conjugates 38 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 12 is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 12, is valuable for creating SNIPERs[1]. | |||
T17887 |
cIAP1 Ligand-Linker Conjugates 15
E3 ligase Ligand-Linker Conjugates 34 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 15 consists of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 15, is suitable for the development of SNIPERs[1]. | |||
T17897 |
cIAP1 Ligand-Linker Conjugates 13
E3 ligase Ligand-Linker Conjugates 43 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 13, containing an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker, are utilized in the development of SNIPERs[1]. | |||
T17900 |
cIAP1 Ligand-Linker Conjugates 8
E3 ligase Ligand-Linker Conjugates 46 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 8 comprises an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is specifically utilized for the purpose of SNIPER design[1]. | |||
T18640 |
(S,R,S)-AHPC-C4-NH2 hydrochloride
VH032-C4-NH2 hydrochloride,E3 ligase Ligand-Linker Conjugates 28,VHL Ligand-Linker Conjugates 13 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) 是一种合成的 E3 连接酶配体- linker 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 linker。 | |||
T17895 |
cIAP1 Ligand-Linker Conjugates 1
E3 ligase Ligand-Linker Conjugates 41 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 1 is composed of an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 1, is particularly useful in the development of SNIPERs[1]. | |||
T17894 |
cIAP1 Ligand-Linker Conjugates 3
E3 ligase Ligand-Linker Conjugates 40 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 3 are chemical compounds comprising an IAP ligand designed specifically for the E3 ubiquitin ligase and a PROTAC linker. These conjugates, denoted as cIAP1 Ligand-Linker Conjugates 3, find utility in the design of SNIPERs, short for Specific and Non-genetic IAP-dependent Protein Erasers [1]. | |||
T17898 |
cIAP1 Ligand-Linker Conjugates 7
E3 ligase Ligand-Linker Conjugates 44 |
Others | Others |
cIAP1 Ligand-Linker Conjugates 7 is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a PROTAC linker. It is utilized in the design of SNIPERs[1]. | |||
T17364 |
AhR Ligand-Linker Conjugates 1
E3 Ligase Ligand-Linker Conjugates 57 |
Others | Others |
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1]. | |||
T17924 |
(S,R,S)-AHPC-PEG2-NH2 hydrochloride
VH032-PEG2-NH2 hydrochloride,VHL Ligand-Linker Conjugates 3 hydrochloride,E3 ligase Ligand-Linker Conjugates 6 |
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 6) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 2 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物,可用于 PROTAC 的合成分子。 | |||
T17888 |
cIAP1 Ligand-Linker Conjugates 6 hydrochloride
E3 ligase Ligand-Linker Conjugates 35 hydrochloride |
Others | Others |
cIAP1 Ligand-Linker Conjugates 6 hydrochloride is a compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. It is utilized for the purpose of designing SNIPERs[1]. | |||
T36268 |
VH 032 Linker 3 (hydrate)
|
||
VH 032 linker 3 is a derivative of the proteolysis-targeting chimera technology (PROTAC) building block VHL ligand 1 . N/A | |||
T9402 |
Thalidomide-O-C4-NH2 hydrochloride
|
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide-O-C4-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 PROTAC 技术中使用的接头,是一种合成的 E3 连接酶配体-接头偶联物。 | |||
T18629 |
PEG3-O-CH2COOH
PROTAC Linker 8,三聚乙二醇-乙酸 |
Others; PROTAC Linker | Others; PROTAC |
PEG3-O-CH2COOH (PROTAC Linker 8) 是一种属于 PEG 类的 PROTAC linker,可用于 SNIPER 分子的合成。 | |||
T17886 |
cIAP1 Ligand-Linker Conjugates 15 hydrochloride
E3 ligase Ligand-Linker Conjugates 34 hydrochloride |
Others | Others |
cIAP1 Ligand-Linker Conjugates 15 hydrochloride is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase and a PROTAC linker. This compound is useful in the development of SNIPERs[1]. | |||
T17884 |
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride
E3 ligase Ligand-Linker Conjugates 33 Hydrochloride |
Others | Others |
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs, a molecular tool for targeted protein degradation[1]. | |||
T17890 |
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride
E3 ligase Ligand-Linker Conjugates 37 Hydrochloride,cIAP1 Ligand-Linker Conjugates 2 Hydrochloride (1312302-14-9 free base) |
Others | Others |
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride is a chemical compound that combines an IAP ligand, which targets the E3 ubiquitin ligase, with a PROTAC linker. It is utilized in the creation of SNIPERs[1]. | |||
T18617 |
NH2-C5-NH-Boc
N-(5-氨基戊基)氨基甲酸叔丁酯,PROTAC Linker 23 |
Others; PROTAC Linker | Others; PROTAC |
NH2-C5-NH-Boc (PROTAC Linker 23) 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18616 |
NH2-C2-NH-Boc
PROTAC Linker 22,N-叔丁氧羰基-1,2-乙二胺 |
Others; PROTAC Linker | Others; PROTAC |
NH2-C2-NH-Boc (PROTAC Linker 22) 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18614 |
Bis-Tos-PEG4
Tetraethylene glycol di(p-toluenesulfonate),PROTAC Linker 16,1,11-Bis(tosyloxy)-3,6,9-trioxaundecane |
Others; PROTAC Linker | Others; PROTAC |
Bis-Tos-PEG4 (PROTAC Linker 16) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T77496L |
AZD 1775 Linker Conjugate 1 TFA
AZD 1775 Linker Conjugate 1 TFA( 2101954-45-2 Free base) |
||
AZD 1775 Linker Conjugate 1 TFA 是一种参与泛素酶靶向嵌合体实验的化合物。 | |||
T18230 |
MAC glucuronide linker-1
|
Others | Others |
MAC glucuronide linker-1 is a nonclaevable ADC linker for antibody-drug-conjugations (ADCs). |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9784 |
Docosanedioic acid
|
PROTAC Linker | PROTAC |
Docosanedioic acid 可以作为ADC linker 或PROTAC linker,用于合成抗体偶联药物或合成 PROTAC。 |