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7

抑制剂 & 化合物

7

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T39477	Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Ca-DTPA trisodium salt hydrate	Others	Others
	Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) 是螯合剂和有用的解毒剂，如急性镉中毒。它是一种无毒的 CMV 复制抑制剂。
T25365	EGA	Others	Others
	EGA 抑制致命毒素的中毒，并阻止多种其他酸依赖性细菌毒素和病毒进入哺乳动物细胞。EGA 是研究膜运输的有力工具，可用于治疗传染病。
T71282	ECANE
	ECANE has the ability to chelate and mobilize cadmium in vivo, making it a good antagonist for cadmium intoxication.
T70641	Asoxime dimethanesulfonate
	Asoxime dimethanesulfonate is an oxime reactivator used for counteracting intoxication by nerve agents. It is able to reactivate acetylcholinesterase (AChE) inhibited by cytotoxic nerve agents such as sarin or soman.
T68624	Asoxime chloride monohydrate
	Asoxime chloride monohydrate is an oxime reactivator used for counteracting intoxication by nerve agents. It is able to reactivate acetylcholinesterase (AChE) inhibited by cytotoxic nerve agents such as sarin or soman.
T62551	ANEB-001
	ANEB-001 是一种口服具有活力的 CB1 抑制剂，能够用于急性大麻素中毒的研究。
T78290	Obiltoxaximab ETI 204
	Obiltoxaximab是一款针对炭疽保护抗原(PA)的高效单克隆抗体。它在阻断炭疽毒素组装及其对靶细胞的毒害中发挥关键作用。此外，Obiltoxaximab也适用于进行吸入性炭疽感染动物模型到人类剂量转换的研究。

化合物

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate

Cat.No: T39477

Synonym: Ca-DTPA trisodium salt hydrate

Target: Others

Cat.No: T25365

Target: Others

Cat.No: T71282

Asoxime dimethanesulfonate

Cat.No: T70641

Asoxime chloride monohydrate

Cat.No: T68624

Cat.No: T62551

Cat.No: T78290

Synonym: ETI 204

Cat. No.	Product Name	Target	Signaling Pathways
T9267	Aureobasidin A	Others; Antifungal	Microbiology/Virology; Others
	Aureobasidin A 是一种环肽和抗真菌抗生素。它是肌醇磷酸神经酰胺合酶 AUR1 的抑制剂。
T4814	(R)-5-Oxopyrrolidine-2-carboxylic acid D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid,D-焦谷氨酸	Others; Endogenous Metabolite	Metabolism; Others
	(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) 是内源性代谢产物的一种。
TC0019	Pregnenolone acetate 孕烯醇酮醋酸酯,3β-Hydroxy-5-pregnen-20-one acetate	Cannabinoid Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism
	Pregnenolone acetate 是一种强大的神经类固醇，是各种类固醇激素（包括类固醇酮）的主要前体。它作为大麻素 CB1 受体的信号特异性抑制剂，抑制由 CB1 受体介导的四氢大麻酚 (THC) 的作用。它可以保护大脑免受大麻中毒。
TN1749	Huperzine C	Others	Others
	Huperzine has the value as pretreatment of organophosphate poisoning, it can be used as a protective agent against organophosphate intoxication.
TN3412	Andrographiside	Others	Others
	Andrographiside shows protective effects on hepatotoxicity induced in mice by carbon tetrachloride or tert-butylhydroperoxide (tBHP) intoxication, the effects could be due to its glucoside groups which may act as strong antioxidants.
T16574	Pregnenolone monosulfate sodium salt 3β-Hydroxy-5-pregnen-20-one monosulfate sodium salt	Others	Others
	Pregnenolone monosulfate sodium salt is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodi
TN3351	Aflatrem	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Aflatrem is a tremorgenic mycotoxin with acute neurotoxic effects, a single low dose of aflatrem is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems. Aflatrem potentiates the gamma-aminobutyric acid (GABA)-induced

天然产物

Cat.No: T9267

Target: Others, Antifungal

(R)-5-Oxopyrrolidine-2-carboxylic acid

Cat.No: T4814

Synonym: D-Pyroglutamic acid,(R)-(+)-2-Pyrrolidone-5-carboxylic acid,D-焦谷氨酸

Target: Others, Endogenous Metabolite

Pregnenolone acetate

Cat.No: TC0019

Synonym: 孕烯醇酮醋酸酯,3β-Hydroxy-5-pregnen-20-one acetate

Target: Cannabinoid Receptor, Endogenous Metabolite

Cat.No: TN1749

Target: Others

Andrographiside

Cat.No: TN3412

Target: Others

Pregnenolone monosulfate sodium salt

Cat.No: T16574

Synonym: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium salt

Target: Others

Cat.No: TN3351

Target: GABA Receptor

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