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7

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T76181	Human milk lysozyme
	Human milk lysozyme，一种在人乳中发现的溶菌酶，被认为是保护新生儿胃肠道免受细菌感染的关键防御因子。
T41160	Lalistat 2	Lipase	Metabolism
	Lalistat 2 是一种溶酶体酸性脂肪酶的特异性抑制剂，IC50 为 152 nM，对人胰脂肪酶或牛乳脂蛋白脂肪酶没有抑制作用（高达 10 μM）。
T38374	2-hydroxy Myristic Acid
	2-hydroxy Myristic acid is a hydroxy fatty acid that has been found in bovine, human, and horse milk, cow and buffalo cheeses, sea bass filet, seal oil, human vernix caseosa, and wool wax. It inhibits cleavage between the enterovirus capsid proteins VP4 and VP2, a process required for enterovirus infectivity, as well as Junin and Tacaribe viral replication (IC50s = 20.1 and 14.2 μM, respectively). 2-hydroxy Myristic acid was previously characterized as a weak inhibitor of peptide myristoylation ...
T38042	Resolvin D4 Resolvin D4,RvD4
	Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.[2][3] RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection. [3] With isolated cells, RvD4 promotes phagocytosi...
T37347	6'-Sialyllactose Sodium Salt 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose
	6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both are major milk oligosaccharides that avidly bind several viral strains, including strains of influenza, HIV-1, reovirus, and polyomavirus.[1],[2],[3],[4],[5],[6] These compounds can be used to differentiate and characterize the binding domains of viruses that recognize N-acetylne...
TMIH-0521	Silibinin-d3
	Silibinin-d3 是 Silibinin 的氘代化合物。Silibinin 的 CAS 号为 22888-70-6。Silibinin 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。
T35854	9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)
	9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co...

化合物

Human milk lysozyme

Cat.No: T76181

Cat.No: T41160

Target: Lipase

2-hydroxy Myristic Acid

Cat.No: T38374

Cat.No: T38042

Synonym: Resolvin D4,RvD4

6'-Sialyllactose Sodium Salt

Cat.No: T37347

Synonym: 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose

Cat.No: TMIH-0521

9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

Cat.No: T35854

Cat. No.	Product Name	Target	Signaling Pathways
TN6796	2'-FUCOSYLLACTOSE 2'-Fucosyl-D-lactose,2'-岩藻糖基乳糖	Others	Others
	2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) 是一种含岩藻糖的寡糖。
T5223	Heneicosanoic acid 二十一碳酸,Heneicosylic Acid,C21:0	Others; Endogenous Metabolite	Metabolism; Others
	Heneicosanoic acid (C21:0) 是广泛存在于动植物中的长链饱和脂肪酸。
T1660	Silibinin 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Silibinin (Silybin) 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。
T5306	H-Abu-OH L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid	Others; Endogenous Metabolite	Metabolism; Others
	H-Abu-OH (L-α-amino-n-Butyric acid) 是氨基丁酸的三个同分异构体之一，它在患有雷氏综合征，同型血尿症，酪氨酸血症，非酮糖症以及鸟氨酸转氨酶症等代谢病儿童的血浆中的含量会明显升高。
T82559	Difucosyllacto-N-neohexaose
	Difucosyllacto-N-neohexaose 是人乳中分离得到的低聚糖。
T81765	Monofucosyllacto-N-hexaose I MFLNH I
	Monofucosyllacto-N-hexaose I (MFLNH I) 作为人乳低聚糖的组分之一, 具有特定的生物学功能。
T81764	Monofucosyllacto-N-hexaose III MFLNH III
	Monofucosyllacto-N-hexaose III（MFLNH III）是一种具有特定生物学功能的中性人乳寡糖（HMO）。
T83274	6′-Galactosyllactose
	6′-Galactosyllactose是人乳中半乳糖主要的低聚糖成分，它能与3′-Galactosyllactose和4′-Galactosyllactose结合，合成人乳低聚糖和半乳糖人工低聚糖，从而减缓T84、NCM-460和H4细胞以及肠道组织的炎症反应。
T81959	Lacto-N-fucopentaose V LNFP V
	Lacto-N-fucopentaose V (LNFP V)为新型五糖，主要存在于人乳及其他生物体液中的低聚糖。
T78481	Lactodifucotetraose 2′,3-Difucosyllactose,Difucosyllactose
	Lactodifucotetraose (Difucosyllactose)，一种四糖，源自人乳。该分子包括D-葡萄糖，D-半乳糖及L-fucose。
T81957	Lacto-N-triose II
	Lacto-N-triose II 作为人乳低聚糖(HMOs)的核心结构单位，具备用于合成复杂HMOs的营养潜力。
T72734	3-Fucosyllactose 3-Fucosyl-D-lactose
	3-Fucosyllactose (3-Fucosyl-D-lactose) 是人类母乳中的主要焦糖之一，具益生元、免疫调节、促进新生儿大脑发育及抗菌功能。
T82545	Disialyllacto-N-tetraose
	Disialyllacto-N-tetraose，一种人乳低聚糖，能预防新生大鼠坏死性小肠结肠炎。
T81960	Lacto-N-difucohexaose II LNDFH II,Lacto-N-fucohexaose
	Lacto-N-difucohexaose II (LNDFH II) 为人乳中的一种重要低聚糖，对婴儿健康具有显著作用。
T81958	Lacto-N-neodifucohexaose II LNnDFH II
	Lacto-N-neodifucohexaose II（Compd 9），一种关键的人乳四糖衍生物，为点击化学反应试剂。该化合物含 Azide 基团，适用于铜催化叠氮-炔环加成反应（CuAAc），与含 Alkyne 基团的分子反应。同时，它也能与含 DBCO 或 BCN 基团的分子，进行菌株促进的炔-叠氮环加成反应（SPAAC）。

天然产物

2'-FUCOSYLLACTOSE

Cat.No: TN6796

Synonym: 2'-Fucosyl-D-lactose,2'-岩藻糖基乳糖

Target: Others

Heneicosanoic acid

Cat.No: T5223

Synonym: 二十一碳酸,Heneicosylic Acid,C21:0

Target: Others, Endogenous Metabolite

Cat.No: T1660

Synonym: 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Cat.No: T5306

Synonym: L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid

Target: Others, Endogenous Metabolite

Difucosyllacto-N-neohexaose

Cat.No: T82559

Monofucosyllacto-N-hexaose I

Cat.No: T81765

Synonym: MFLNH I

Monofucosyllacto-N-hexaose III

Cat.No: T81764

Synonym: MFLNH III

6′-Galactosyllactose

Cat.No: T83274

Lacto-N-fucopentaose V

Cat.No: T81959

Synonym: LNFP V

Lactodifucotetraose

Cat.No: T78481

Synonym: 2′,3-Difucosyllactose,Difucosyllactose

Lacto-N-triose II

Cat.No: T81957

3-Fucosyllactose

Cat.No: T72734

Synonym: 3-Fucosyl-D-lactose

Disialyllacto-N-tetraose

Cat.No: T82545

Lacto-N-difucohexaose II

Cat.No: T81960

Synonym: LNDFH II,Lacto-N-fucohexaose

Lacto-N-neodifucohexaose II

Cat.No: T81958

Synonym: LNnDFH II

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