Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15159 |
Dorzagliatin
HMS5552 |
Glucokinase | Metabolism |
Dorzagliatin (HMS5552) 是双重作用的葡萄糖激酶 (glucokinase;GK) 激活剂,可改善 2 型糖尿病的血糖控制,提高胰腺 β 细胞功能。 | |||
T62656 |
GPR81 agonist 1
|
GPR | Endocrinology/Hormones; GPCR/G Protein |
GPR81 agonist 1 是一种具有高效性和选择性的 GPR81 激动剂,对人和小鼠 GPR81 具有很高的亲和力。GPR81 agonist 1 抑制分化的 3T3-L1 脂肪细胞的脂解,改善胰岛素抵抗和糖尿病小鼠模型的胰岛素敏感性和血糖控制,可用于研究糖尿病和肥胖。 | |||
TP1566 |
GIP (1-30) amide (Human) (TFA)
|
||
GIP (1-30) amide (Human) TFA is a glucose-dependent insulinotropic polypeptide fragment. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. | |||
T64475 |
FMOC-L-THR
|
||
FMOC-L-THR (AZP-531) is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA, making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a m... |