Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1069 |
Metoclopramide hydrochloride
盐酸甲氧氯普胺,Maxolon,Metoclopramide HCl |
Dopamine Receptor; 5-HT Receptor; AChR | GPCR/G Protein; Neuroscience |
Metoclopramide hydrochloride (Metoclopramide HCl) 是可口服的5-HT3和多巴胺D2受体拮抗剂,IC50值分别为 308 和 483 nM,用于恶心呕吐、胃食管反流和胃轻瘫的研究。 | |||
T4616 |
Metoclopramide
甲氧氯普胺,胃复安,5-Chloro-2-methoxyprocainamide |
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
Metoclopramide (5-Chloro-2-methoxyprocainamide) 是5-HT3和多巴胺D2受体拮抗剂,IC50值分别为 308 和 483 nM,可用于恶心呕吐、胃食管反流和胃轻瘫的研究。 | |||
T8385 |
Metoclopramide hydrochloride hydrate
盐酸甲氧氯普胺,甲氧氯普胺盐酸水合物,Metoclopramide monohydrochloride monohydrate |
Dopamine Receptor; 5-HT Receptor | GPCR/G Protein; Neuroscience |
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) 是5-HT3和多巴胺D2受体拮抗剂,IC50值分别为 308 和 483 nM,可用于恶心呕吐、胃食管反流和胃轻瘫的研究。 | |||
T38754 |
Trazpiroben
TAK-906 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Trazpiroben (TAK-906) 是一种选择性多巴胺 D2/D3 受体拮抗剂,用于研究胃痉挛。 | |||
TP2403 |
Recanaclotide
IW 9179,IW-9179,IW9179 |
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Recanaclotide can be used to treat Gastroparesis, Functional Dyspepsia, and Other Gastrointestinal Disorders. | |||
T71632 |
TZP-102
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TZP-102 is a potent, oral, ghrelin receptor agonist that has been shown to improve diabetic gastroparesis symptoms. | |||
T35046 |
Velusetrag
TD 5108,TD5108,TD-5108 |
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Velusetrag(TD-5108)is an effective, selective, and highly potent agonist of the 5-HT4 receptor, and being developed for the treatment of gastroparesis, chronic constipation, and irritable bowel syndrome. | |||
T62973 |
DS-3801b
|
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DS-3801b 是一种强效的、非大环内酯类 GPR38 激动剂。DS-3801b 具有潜力成为研究功能性胃肠道疾病(如胃痉挛、慢性便秘)的新型胃肠道促动剂。 | |||
T39236 |
Relamorelin acetate
Relamorelin acetate,RM-131 acetate,BIM-28131acetate |
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Relamorelin (RM-131) acetate is a pentapeptide ghrelin analog that acts as a selective agonist for the ghrelin/growth hormone secretagogue receptor (GHSR). It exhibits a high affinity for the GHS-1a receptor, with a Ki value of 0.42 nM. Notably, Relamorelin acetate can cross the blood-brain barrier and target the central nervous system. This compound effectively increases growth hormone levels and promotes faster gastric emptying. Due to these properties, Relamorelin acetate holds promise for it... | |||
T75262 |
Relamorelin TFA
|
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Relamorelin (RM-131) TFA,一种生长素类似物,是一种选择性的生长素释放肽/生长激素促分泌素受体 (GHSR) 激动剂,对GHS-1a 受体的Ki 值为 0.42 nM。Relamorelin TFA 是一种五肽,具有中枢渗透性。Relamorelin TFA 增加生长激素水平,加速胃排空,具有用于恶病质、胃轻瘫和胃/肠运动障碍研究的潜力。 |