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Search Results for " gastrointestinal inflammatory diseases "

4

抑制剂 & 化合物

2

天然产物

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Cat. No. Product Name Target Signaling Pathways
T38612 Linaprazan glurate

Others Others
Linaprazan glurate 抑制外源性或内源性刺激的胃酸分泌。 Linaprazan glurate 可用于胃肠道炎症性疾病和消化性溃疡疾病的研究。
T10121 Substance P Receptor Antagonist 1

Others Others
Substance P Receptor Antagonist 1 has the potential function in gastrointestinal disorders, inflammatory diseases, respiratory, and central nervous system disorders.
T39583 Zastaprazan

Zastaprazan, a proton pump inhibitor (WO2018008929), is utilized in the research of gastrointestinal inflammatory diseases and conditions related to gastric acid.
T71179 LON63114

LON63114, also known as FFA2-Agonist-1 is a selective orthosteric agonist of human FFA2. FFA2-Agonist-1 is potentially useful in the treatment of gastrointestinal disorders and inflammatory bowel diseases. LON63114 was reported in WO2011076732. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

化合物

Linaprazan glurate
Cat.No: T38612
Synonym:
Target: Others
Substance P Receptor Antagonist 1
Cat.No: T10121
Synonym:
Target: Others
Zastaprazan
Cat.No: T39583
Synonym:
Target:
LON63114
Cat.No: T71179
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1834 Kobusin

去甲槟郎碱,自旋七叶素

Others; NOS; NF-κB Immunology/Inflammation; NF-κB; Others
Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-express...
T38108 Fulvic Acid

Antioxidant; PDE Metabolism; oxidation-reduction
Fulvic Acid 是一种来自土壤、沉积物或水生环境中微生物产生的腐殖质的天然产物,是一种首次青霉菌中分离出的酚酸和真菌代谢产物。Fulvic Acid 抑制淀粉样蛋白b (17-42) (AB17-42)二聚化,破坏预先形成的AB17-42三聚体,并结合到磷酸二酯酶5A (PDE5A)的催化位点,可以调节机体免疫系统,影响细胞的氧化状态,改善胃肠功能。Fulvic Acid 可作为氧化剂或还原剂, 具有研究糖尿病等慢性炎症性疾病的潜力。

天然产物

Kobusin
Cat.No: TN1834
Synonym: 去甲槟郎碱,自旋七叶素
Target: Others, NOS, NF-κB
Fulvic Acid
Cat.No: T38108
Synonym:
Target: Antioxidant, PDE
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